Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle

Antioxidants and Redox Signaling

Volumn 24, Issue 2, 2016, Pages 84-98

  Bouitbir, Jamal ^a,b,c   Singh, François ^a,b,d   Charles, Anne Laure ^a   Schlagowski, Anna Isabel ^a,b   Bonifacio, Annalisa ^d   Echaniz Laguna, Andoni ^b   Geny, Bernard ^a,b   Krahenbuhl, Stephan ^c,d   Zoll, Joffrey ^a,b,e  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^c Swiss Centre for Applied Human Toxicology   (Switzerland)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e HÔPITAL CIVIL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CASPASE 3; CREATINE KINASE; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MALIC ACID; MESSENGER RNA; MEVALONIC ACID; PRAVASTATIN; PROTEIN BAX; PROTEIN BCL 2; QUERCETIN; REACTIVE OXYGEN METABOLITE; ROSUVASTATIN; SIMVASTATIN; SUPEROXIDE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DELTOID MUSCLE; DNA STRAND BREAKAGE; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GLYCOLYSIS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE AGED; MITOCHONDRIAL RESPIRATION; MUSCLE BIOPSY; MYOBLAST; MYOPATHY; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLANTARIS MUSCLE; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; TUNEL ASSAY; VERY ELDERLY; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MUSCLE DISEASE; WISTAR RAT;

ANIMALS; APOPTOSIS; DELTOID MUSCLE; GLYCOLYSIS; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MITOCHONDRIA; MUSCLE, SKELETAL; MUSCULAR DISEASES; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84954535343     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.6190     Document Type: Article

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