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Volumn 35, Issue 6, 2015, Pages 737-749

Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CADHERIN; DROSOPHILA PROTEIN; MATS PROTEIN; MORPHOGEN; MPS1 ONE BINDER PROTEIN; MYOSIN; NUCLEAR DBF2 RELATED KINASE; PHOSPHOTRANSFERASE; PROTOCADHERIN DACHSOUS; PROTOCADHERIN FAT; UNCLASSIFIED DRUG; WARTS KINASE; CELL ADHESION MOLECULE; DACHSOUS PROTEIN, DROSOPHILA; FAT PROTEIN, DROSOPHILA; PROTEIN SERINE THREONINE KINASE; TRICORNERED PROTEIN, DROSOPHILA;

EID: 84954523154     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2015.11.027     Document Type: Article
Times cited : (49)

References (63)
  • 1
    • 33947095101 scopus 로고    scopus 로고
    • Model for the regulation of size in the wing imaginal disc of Drosophila
    • Aegerter-Wilmsen T., Aegerter C.M., Hafen E., Basler K. Model for the regulation of size in the wing imaginal disc of Drosophila. Mech. Dev. 2007, 124:318-326.
    • (2007) Mech. Dev. , vol.124 , pp. 318-326
    • Aegerter-Wilmsen, T.1    Aegerter, C.M.2    Hafen, E.3    Basler, K.4
  • 2
    • 42949146948 scopus 로고    scopus 로고
    • Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors
    • Ai H.W., Hazelwood K.L., Davidson M.W., Campbell R.E. Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors. Nat. Methods 2008, 5:401-403.
    • (2008) Nat. Methods , vol.5 , pp. 401-403
    • Ai, H.W.1    Hazelwood, K.L.2    Davidson, M.W.3    Campbell, R.E.4
  • 4
    • 33750611115 scopus 로고    scopus 로고
    • Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway
    • Bennett F.C., Harvey K.F. Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway. Curr. Biol. 2006, 16:2101-2110.
    • (2006) Curr. Biol. , vol.16 , pp. 2101-2110
    • Bennett, F.C.1    Harvey, K.F.2
  • 5
    • 4143117852 scopus 로고    scopus 로고
    • Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein
    • Bichsel S.J., Tamaskovic R., Stegert M.R., Hemmings B.A. Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein. J. Biol. Chem. 2004, 279:35228-35235.
    • (2004) J. Biol. Chem. , vol.279 , pp. 35228-35235
    • Bichsel, S.J.1    Tamaskovic, R.2    Stegert, M.R.3    Hemmings, B.A.4
  • 7
    • 77953127131 scopus 로고    scopus 로고
    • Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat
    • Brittle A.L., Repiso A., Casal J., Lawrence P.A., Strutt D. Four-jointed modulates growth and planar polarity by reducing the affinity of dachsous for fat. Curr. Biol. 2010, 20:803-810.
    • (2010) Curr. Biol. , vol.20 , pp. 803-810
    • Brittle, A.L.1    Repiso, A.2    Casal, J.3    Lawrence, P.A.4    Strutt, D.5
  • 8
    • 84861527829 scopus 로고    scopus 로고
    • Planar polarity specification through asymmetric subcellular localization of Fat and Dachsous
    • Brittle A., Thomas C., Strutt D. Planar polarity specification through asymmetric subcellular localization of Fat and Dachsous. Curr. Biol. 2012, 22:907-914.
    • (2012) Curr. Biol. , vol.22 , pp. 907-914
    • Brittle, A.1    Thomas, C.2    Strutt, D.3
  • 9
    • 68049093089 scopus 로고    scopus 로고
    • Fluorescent-protein-based biosensors: modulation of energy transfer as a design principle
    • Campbell R.E. Fluorescent-protein-based biosensors: modulation of energy transfer as a design principle. Anal. Chem. 2009, 81:5972-5979.
    • (2009) Anal. Chem. , vol.81 , pp. 5972-5979
    • Campbell, R.E.1
  • 10
    • 0037162283 scopus 로고    scopus 로고
    • Developmental compartments and planar polarity in Drosophila
    • Casal J., Struhl G., Lawrence P.A. Developmental compartments and planar polarity in Drosophila. Curr. Biol. 2002, 12:1189-1198.
    • (2002) Curr. Biol. , vol.12 , pp. 1189-1198
    • Casal, J.1    Struhl, G.2    Lawrence, P.A.3
  • 11
    • 33845288905 scopus 로고    scopus 로고
    • Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity
    • Casal J., Lawrence P.A., Struhl G. Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity. Development 2006, 133:4561-4572.
    • (2006) Development , vol.133 , pp. 4561-4572
    • Casal, J.1    Lawrence, P.A.2    Struhl, G.3
  • 14
    • 0029048545 scopus 로고
    • Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila
    • Clark H.F., Brentrup D., Schneitz K., Bieber A., Goodman C., Noll M. Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila. Genes Dev. 1995, 9:1530-1542.
    • (1995) Genes Dev. , vol.9 , pp. 1530-1542
    • Clark, H.F.1    Brentrup, D.2    Schneitz, K.3    Bieber, A.4    Goodman, C.5    Noll, M.6
  • 15
    • 84885803646 scopus 로고    scopus 로고
    • Hippo gains weight: added insights and complexity to pathway control
    • Enderle L., McNeill H. Hippo gains weight: added insights and complexity to pathway control. Sci. Signal. 2013, 6:re7.
    • (2013) Sci. Signal. , vol.6 , pp. re7
    • Enderle, L.1    McNeill, H.2
  • 17
    • 0025907542 scopus 로고
    • Site-specific recombination between homologous chromosomes in Drosophila
    • Golic K.G. Site-specific recombination between homologous chromosomes in Drosophila. Science 1991, 252:958-961.
    • (1991) Science , vol.252 , pp. 958-961
    • Golic, K.G.1
  • 18
    • 84865411430 scopus 로고    scopus 로고
    • Transduction of mechanical and cytoskeletal cues by YAP and TAZ
    • Halder G., Dupont S., Piccolo S. Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 2012, 13:591-600.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 591-600
    • Halder, G.1    Dupont, S.2    Piccolo, S.3
  • 19
    • 30344445706 scopus 로고    scopus 로고
    • The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
    • Hamaratoglu F., Willecke M., Kango-Singh M., Nolo R., Hyun E., Tao C., Jafar-Nejad H., Halder G. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat. Cell Biol. 2006, 8:27-36.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 27-36
    • Hamaratoglu, F.1    Willecke, M.2    Kango-Singh, M.3    Nolo, R.4    Hyun, E.5    Tao, C.6    Jafar-Nejad, H.7    Halder, G.8
  • 20
    • 41949138130 scopus 로고    scopus 로고
    • Tumor suppressor LATS1 is a negative regulator of oncogene YAP
    • Hao Y., Chun A., Cheung K., Rashidi B., Yang X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J. Biol. Chem. 2008, 283:5496-5509.
    • (2008) J. Biol. Chem. , vol.283 , pp. 5496-5509
    • Hao, Y.1    Chun, A.2    Cheung, K.3    Rashidi, B.4    Yang, X.5
  • 21
    • 24344463858 scopus 로고    scopus 로고
    • Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases
    • He Y., Emoto K., Fang X., Ren N., Tian X., Jan Y.N., Adler P.N. Drosophila Mob family proteins interact with the related tricornered (Trc) and warts (Wts) kinases. Mol. Biol. Cell 2005, 16:4139-4152.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4139-4152
    • He, Y.1    Emoto, K.2    Fang, X.3    Ren, N.4    Tian, X.5    Jan, Y.N.6    Adler, P.N.7
  • 22
    • 84883068191 scopus 로고    scopus 로고
    • Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling
    • Hergovich A. Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling. Cell Biosci. 2013, 3:32.
    • (2013) Cell Biosci. , vol.3 , pp. 32
    • Hergovich, A.1
  • 23
    • 33646422520 scopus 로고    scopus 로고
    • The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
    • Hergovich A., Schmitz D., Hemmings B.A. The human tumour suppressor LATS1 is activated by human MOB1 at the membrane. Biochem. Biophys. Res. Commun. 2006, 345:50-58.
    • (2006) Biochem. Biophys. Res. Commun. , vol.345 , pp. 50-58
    • Hergovich, A.1    Schmitz, D.2    Hemmings, B.A.3
  • 25
    • 72649099866 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila
    • Ho L.L., Wei X., Shimizu T., Lai Z.C. Mob as tumor suppressor is activated at the cell membrane to control tissue growth and organ size in Drosophila. Dev. Biol. 2010, 337:274-283.
    • (2010) Dev. Biol. , vol.337 , pp. 274-283
    • Ho, L.L.1    Wei, X.2    Shimizu, T.3    Lai, Z.C.4
  • 26
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • Huang J., Wu S., Barrera J., Matthews K., Pan D. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 2005, 122:421-434.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 28
    • 0028902594 scopus 로고
    • The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
    • Justice R.W., Zilian O., Woods D.F., Noll M., Bryant P.J. The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev. 1995, 9:534-546.
    • (1995) Genes Dev. , vol.9 , pp. 534-546
    • Justice, R.W.1    Zilian, O.2    Woods, D.F.3    Noll, M.4    Bryant, P.J.5
  • 31
    • 0030604688 scopus 로고    scopus 로고
    • Morphogens, compartments, and pattern: lessons from Drosophila?
    • Lawrence P.A., Struhl G. Morphogens, compartments, and pattern: lessons from Drosophila?. Cell 1996, 85:951-961.
    • (1996) Cell , vol.85 , pp. 951-961
    • Lawrence, P.A.1    Struhl, G.2
  • 32
    • 0033103536 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis
    • Lee T., Luo L. Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron 1999, 22:451-461.
    • (1999) Neuron , vol.22 , pp. 451-461
    • Lee, T.1    Luo, L.2
  • 33
    • 84884217043 scopus 로고    scopus 로고
    • A global pattern of mechanical stress polarizes cell divisions and cell shape in the growing Drosophila wing disc
    • Legoff L., Rouault H., Lecuit T. A global pattern of mechanical stress polarizes cell divisions and cell shape in the growing Drosophila wing disc. Development 2013, 140:4051-4059.
    • (2013) Development , vol.140 , pp. 4051-4059
    • Legoff, L.1    Rouault, H.2    Lecuit, T.3
  • 34
    • 33746410714 scopus 로고    scopus 로고
    • Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila
    • Mao Y., Rauskolb C., Cho E., Hu W.L., Hayter H., Minihan G., Katz F.N., Irvine K.D. Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila. Development 2006, 133:2539-2551.
    • (2006) Development , vol.133 , pp. 2539-2551
    • Mao, Y.1    Rauskolb, C.2    Cho, E.3    Hu, W.L.4    Hayter, H.5    Minihan, G.6    Katz, F.N.7    Irvine, K.D.8
  • 35
    • 84887086134 scopus 로고    scopus 로고
    • Differential proliferation rates generate patterns of mechanical tension that orient tissue growth
    • Mao Y., Tournier A.L., Hoppe A., Kester L., Thompson B.J., Tapon N. Differential proliferation rates generate patterns of mechanical tension that orient tissue growth. EMBO J. 2013, 32:2790-2803.
    • (2013) EMBO J. , vol.32 , pp. 2790-2803
    • Mao, Y.1    Tournier, A.L.2    Hoppe, A.3    Kester, L.4    Thompson, B.J.5    Tapon, N.6
  • 36
    • 33745899356 scopus 로고    scopus 로고
    • Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins
    • Matakatsu H., Blair S.S. Separating the adhesive and signaling functions of the Fat and Dachsous protocadherins. Development 2006, 133:2315-2324.
    • (2006) Development , vol.133 , pp. 2315-2324
    • Matakatsu, H.1    Blair, S.S.2
  • 37
    • 84908176718 scopus 로고    scopus 로고
    • The balance of prickle/spiny-legs isoforms controls the amount of coupling between core and fat PCP systems
    • Merkel M., Sagner A., Gruber F.S., Etournay R., Blasse C., Myers E., Eaton S., Jülicher F. The balance of prickle/spiny-legs isoforms controls the amount of coupling between core and fat PCP systems. Curr. Biol. 2014, 24:2111-2123.
    • (2014) Curr. Biol. , vol.24 , pp. 2111-2123
    • Merkel, M.1    Sagner, A.2    Gruber, F.S.3    Etournay, R.4    Blasse, C.5    Myers, E.6    Eaton, S.7    Jülicher, F.8
  • 38
    • 84936998216 scopus 로고    scopus 로고
    • Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling
    • Ni L., Zheng Y., Hara M., Pan D., Luo X. Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling. Genes Dev. 2015, 29:1416-1431.
    • (2015) Genes Dev. , vol.29 , pp. 1416-1431
    • Ni, L.1    Zheng, Y.2    Hara, M.3    Pan, D.4    Luo, X.5
  • 39
    • 70350586741 scopus 로고    scopus 로고
    • Determination of mechanical stress distribution in Drosophila wing discs using photoelasticity
    • Nienhaus U., Aegerter-Wilmsen T., Aegerter C.M. Determination of mechanical stress distribution in Drosophila wing discs using photoelasticity. Mech. Dev. 2009, 126:942-949.
    • (2009) Mech. Dev. , vol.126 , pp. 942-949
    • Nienhaus, U.1    Aegerter-Wilmsen, T.2    Aegerter, C.M.3
  • 41
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • Pan D. The hippo signaling pathway in development and cancer. Dev. Cell 2010, 19:491-505.
    • (2010) Dev. Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 42
    • 40149111984 scopus 로고    scopus 로고
    • MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
    • Praskova M., Xia F., Avruch J. MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. Curr. Biol. 2008, 18:311-321.
    • (2008) Curr. Biol. , vol.18 , pp. 311-321
    • Praskova, M.1    Xia, F.2    Avruch, J.3
  • 43
    • 84903938032 scopus 로고    scopus 로고
    • Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex
    • Rauskolb C., Sun S., Sun G., Pan Y., Irvine K.D. Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex. Cell 2014, 158:143-156.
    • (2014) Cell , vol.158 , pp. 143-156
    • Rauskolb, C.1    Sun, S.2    Sun, G.3    Pan, Y.4    Irvine, K.D.5
  • 44
    • 48749101754 scopus 로고    scopus 로고
    • Morphogen control of wing growth through the Fat signaling pathway
    • Rogulja D., Rauskolb C., Irvine K.D. Morphogen control of wing growth through the Fat signaling pathway. Dev. Cell 2008, 15:309-321.
    • (2008) Dev. Cell , vol.15 , pp. 309-321
    • Rogulja, D.1    Rauskolb, C.2    Irvine, K.D.3
  • 45
    • 14744273475 scopus 로고    scopus 로고
    • Mechanical feedback as a possible regulator of tissue growth
    • Shraiman B.I. Mechanical feedback as a possible regulator of tissue growth. Proc. Natl. Acad. Sci. USA 2005, 102:3318-3323.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 3318-3323
    • Shraiman, B.I.1
  • 46
    • 77953324959 scopus 로고    scopus 로고
    • Modulation of fat:dachsous binding by the cadherin domain kinase four-jointed
    • Simon M.A., Xu A., Ishikawa H.O., Irvine K.D. Modulation of fat:dachsous binding by the cadherin domain kinase four-jointed. Curr. Biol. 2010, 20:811-817.
    • (2010) Curr. Biol. , vol.20 , pp. 811-817
    • Simon, M.A.1    Xu, A.2    Ishikawa, H.O.3    Irvine, K.D.4
  • 47
    • 80755162531 scopus 로고    scopus 로고
    • Hippo signaling in Drosophila: recent advances and insights
    • Staley B.K., Irvine K.D. Hippo signaling in Drosophila: recent advances and insights. Dev. Dyn. 2012, 241:3-15.
    • (2012) Dev. Dyn. , vol.241 , pp. 3-15
    • Staley, B.K.1    Irvine, K.D.2
  • 48
    • 28544435761 scopus 로고    scopus 로고
    • Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3
    • Stegert M.R., Hergovich A., Tamaskovic R., Bichsel S.J., Hemmings B.A. Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3. Mol. Cell. Biol. 2005, 25:11019-11029.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 11019-11029
    • Stegert, M.R.1    Hergovich, A.2    Tamaskovic, R.3    Bichsel, S.J.4    Hemmings, B.A.5
  • 49
    • 0027479044 scopus 로고
    • Organizing activity of wingless protein in Drosophila
    • Struhl G., Basler K. Organizing activity of wingless protein in Drosophila. Cell 1993, 72:527-540.
    • (1993) Cell , vol.72 , pp. 527-540
    • Struhl, G.1    Basler, K.2
  • 50
    • 1342306067 scopus 로고    scopus 로고
    • Morphogens, their identification and regulation
    • Tabata T., Takei Y. Morphogens, their identification and regulation. Development 2004, 131:703-712.
    • (2004) Development , vol.131 , pp. 703-712
    • Tabata, T.1    Takei, Y.2
  • 51
    • 0032954260 scopus 로고    scopus 로고
    • Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity
    • Tao W., Zhang S., Turenchalk G.S., Stewart R.A., St John M.A., Chen W., Xu T. Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity. Nat. Genet. 1999, 21:177-181.
    • (1999) Nat. Genet. , vol.21 , pp. 177-181
    • Tao, W.1    Zhang, S.2    Turenchalk, G.S.3    Stewart, R.A.4    St John, M.A.5    Chen, W.6    Xu, T.7
  • 52
    • 0025249807 scopus 로고
    • Practical design criteria for a dynamic ratio imaging system
    • Tsien R.Y., Harootunian A.T. Practical design criteria for a dynamic ratio imaging system. Cell Calcium 1990, 11:93-109.
    • (1990) Cell Calcium , vol.11 , pp. 93-109
    • Tsien, R.Y.1    Harootunian, A.T.2
  • 53
    • 0029160929 scopus 로고
    • Four-jointed is required for intermediate growth in the proximal-distal axis in Drosophila
    • Villano J.L., Katz F.N. four-jointed is required for intermediate growth in the proximal-distal axis in Drosophila. Development 1995, 121:2767-2777.
    • (1995) Development , vol.121 , pp. 2767-2777
    • Villano, J.L.1    Katz, F.N.2
  • 54
    • 34247182696 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
    • Wei X., Shimizu T., Lai Z.C. Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J. 2007, 26:1772-1781.
    • (2007) EMBO J. , vol.26 , pp. 1772-1781
    • Wei, X.1    Shimizu, T.2    Lai, Z.C.3
  • 56
    • 54449090287 scopus 로고    scopus 로고
    • Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation
    • Willecke M., Hamaratoglu F., Sansores-Garcia L., Tao C., Halder G. Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation. Proc. Natl. Acad. Sci. USA 2008, 105:14897-14902.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 14897-14902
    • Willecke, M.1    Hamaratoglu, F.2    Sansores-Garcia, L.3    Tao, C.4    Halder, G.5
  • 57
  • 58
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase
    • Xu T., Wang W., Zhang S., Stewart R.A., Yu W. Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 1995, 121:1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5
  • 59
    • 0037040407 scopus 로고    scopus 로고
    • Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye
    • Yang C.H., Axelrod J.D., Simon M.A. Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye. Cell 2002, 108:675-688.
    • (2002) Cell , vol.108 , pp. 675-688
    • Yang, C.H.1    Axelrod, J.D.2    Simon, M.A.3
  • 60
    • 0036295728 scopus 로고    scopus 로고
    • Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation
    • Yang J., Cron P., Thompson V., Good V.M., Hess D., Hemmings B.A., Barford D. Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation. Mol. Cell 2002, 9:1227-1240.
    • (2002) Mol. Cell , vol.9 , pp. 1227-1240
    • Yang, J.1    Cron, P.2    Thompson, V.3    Good, V.M.4    Hess, D.5    Hemmings, B.A.6    Barford, D.7
  • 61
    • 84884291548 scopus 로고    scopus 로고
    • Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
    • Yin F., Yu J., Zheng Y., Chen Q., Zhang N., Pan D. Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell 2013, 154:1342-1355.
    • (2013) Cell , vol.154 , pp. 1342-1355
    • Yin, F.1    Yu, J.2    Zheng, Y.3    Chen, Q.4    Zhang, N.5    Pan, D.6
  • 62
    • 34548552727 scopus 로고    scopus 로고
    • Control of Drosophila wing growth by the vestigial quadrant enhancer
    • Zecca M., Struhl G. Control of Drosophila wing growth by the vestigial quadrant enhancer. Development 2007, 134:3011-3020.
    • (2007) Development , vol.134 , pp. 3011-3020
    • Zecca, M.1    Struhl, G.2
  • 63
    • 77954740913 scopus 로고    scopus 로고
    • A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth
    • Zecca M., Struhl G. A feed-forward circuit linking wingless, fat-dachsous signaling, and the warts-hippo pathway to Drosophila wing growth. PLoS Biol. 2010, 8:e1000386.
    • (2010) PLoS Biol. , vol.8 , pp. e1000386
    • Zecca, M.1    Struhl, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.