Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolism

Free Radical Biology and Medicine

Volumn 91, Issue , 2016, Pages 143-153

  Ravi, Saranya ^a,b,c   Johnson, Michelle S ^a,b,c   Chacko, Balu K ^a,b,c   Kramer, Philip A ^a,b,c   Sawada, Hirotaka ^a,b,c   Locy, Morgan L ^a,b,c   Wilson, Landon S ^d   Barnes, Stephen ^d,e   Marques, Marisa B ^a   Darley Usmar, Victor M ^a,b,c,f  

^a Department of Pathology ^*  (United States)

^b UAB Mitochondrial Medicine Laboratory   (United States)

^c Center for Free Radical Biology   (United States)

^d Targeted Metabolomics and Proteomics Laboratory   (United States)

^e University of Alabama at Birmingham   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

4 hydroxynonenal; Aggregation; Bioenergetics; Click chemistry; Metabolomics; Platelet

Indexed keywords

4 HYDROXYNONENAL; ALCOHOL; ALKYNE; FREE RADICAL; LACTATE DEHYDROGENASE; NONANAL; NONANOL; THROMBIN; THROMBOCYTE CONCENTRATE; TRICARBOXYLIC ACID; 4-HYDROXY-2-NONENAL; ALDEHYDE; PROTEOME;

ARTICLE; BIOENERGY; BIOLOGICAL ACTIVITY; BLOOD CLOTTING; CARDIOPULMONARY BYPASS; CLICK CHEMISTRY; CLINICAL ARTICLE; CONTROLLED STUDY; GLYCOLYSIS; HUMAN; HUMAN CELL; KIDNEY FAILURE; MASS SPECTROMETRY; METABOLOMICS; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN MODIFICATION; SEPTIC SHOCK; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTE METABOLISM; CITRIC ACID CYCLE; DRUG EFFECTS; ENERGY METABOLISM; METABOLISM; PHYSIOLOGY; THROMBOCYTE;

ALDEHYDES; BLOOD PLATELETS; CITRIC ACID CYCLE; ENERGY METABOLISM; GLYCOLYSIS; HUMANS; PLATELET AGGREGATION; PROTEOME; THROMBIN;

EID: 84954518443     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.10.408     Document Type: Article

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