Tauroursodeoxycholic acid suppresses endoplasmic reticulum stress in pulmonary tissues of intermittent hypoxia mice

Journal of Central South University (Medical Sciences)

Volumn 40, Issue 11, 2015, Pages 1165-1172

  Shi, Zhihui ^a   Xu, Linhao ^a   Zhou, Rui ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Endoplasmic reticulum stress; Intermittent hypoxia model; Obstructive sleep apnea syndrome; Tauroursodeoxycholic acid

Indexed keywords

CASP12 PROTEIN, MOUSE; CASP3 PROTEIN, MOUSE; CASPASE 12; CASPASE 3; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; TAUROCHENODEOXYCHOLIC ACID; TAUROURSODEOXYCHOLIC ACID;

ANIMAL; ANOXIA; APOPTOSIS; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; LUNG; METABOLISM; MOUSE; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; ANOXIA; APOPTOSIS; CASPASE 12; CASPASE 3; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; LUNG; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; TAUROCHENODEOXYCHOLIC ACID; TRANSCRIPTION FACTOR CHOP;

EID: 84954509246     PISSN: 16727347     EISSN: None     Source Type: Journal    
DOI: 10.11817/j.issn.1672-7347.2015.11.001     Document Type: Article

References (28)

1. Appelberg J, Janson C, Lindberg E, et al. Lung aeration during sleep in patients with obstructive sleep apnoea[J]. Clin Physiol Funct Imaging, 2010, 30(4): 301-307.
2. Sériès F, Cormier Y, La Forge J. Role of lung volumes in sleep apnoea-related oxygen desaturation[J]. Eur Respir J, 1989, 2(1): 26-30.
3. Zieliński J. Effects of intermittent hypoxia on pulmonary haemodynamics: animal models versus studies in humans[J]. Eur Respir J, 2005, 25(1): 173-180.
4. Chhunchha B, Fatma N, Kubo E, et al. Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-KB regulation[J]. Am J Physiol Cell Physiol, 2013, 304(7): C636-655.
5. - cotransporter[J]. J Neurochem, 2008, 106(4): 1563-1576.
6. Koyama M, Furuhashi M, Ishimura S, et al. Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension[J]. Am J Physiol Heart Circ Physiol, 2014, 306(9): H1314-H1323.
7. Wei J, Rahman S, Ayaub EA, et al. Protein misfolding and endoplasmic reticulum stress in chronic lung disease[J]. Chest, 2013, 143(4): 1098-1105.
8. Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation [J]. Science, 2011, 334(6059): 1081-1086.
9. Yamaji-Kegan K, Takimoto E, Zhang A, et al. Hypoxia-induced mitogenic factor (FIZZ1/RELMα) induces endothelial cell apoptosis and subsequent interleukin-4-dependent pulmonary hypertension[J]. Am J Physiol Lung Cell Mol Physiol, 2014, 306(12): L1090-1103.
10. Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of Type 2 diabetes[J]. Science, 2006, 313 (5790): 1137-1140.
11. Xie Q, Khaoustov VI, Chung CC, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation[J]. Hepatology, 2002, 36(3): 592-601.
12. Henkel AS, Dewey AM, Anderson KA, et al. Reducing endoplasmic reticulum stress does not improve steatohepatitis in mice fed a methionine- and choline-deficient diet[J]. Am J Physiol Gastrointest Liver Physiol, 2012, 303(1): G54-G59.
13. Xu L, Xie H, Shi ZH, et al. Critical role of endoplasmic reticulum stress in chronic intermittent hypoxia-induced deficits in synaptic plasticity and long-term memory[J]. Antioxid Redox Signal, 2015, 23(9): 695-710.
14. Xie H, Leung KL, Chen L, et al. Brain-derived neurotrophic factor rescues and prevents chronic intermittent hypoxia-induced impairment of hippocampal long-term synaptic plasticity [J]. Neurobiol Dis, 2010, 40(1): 155-162.
15. Hetz C, Chevet E, Harding HP. Targeting the unfolded protein response in disease[J]. Nat Rev Drug Discov, 2013, 12(9): 703-719.
16. Wang S, Kaufman RJ. The impact of the unfolded protein response on human disease[J]. J Cell Biol, 2012, 197(7): 857-867.
17. Ding W, Zhang X, Huang H, et al. Adiponectin protects rat myocardium against chronic intermittent hypoxia-induced injury via inhibition of endoplasmic reticulum stress[J]. PLoS One, 2014, 9(4): e94545.
18. Cai XH, Li XC, Jin SW, et al. Endoplasmic reticulum stress plays critical role in brain damage after chronic intermittent hypoxia in growing rats[J]. Exp Neurol, 2014, 257(6):148-156.
19. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response[J]. Nat Rev Mol Cell Biol, 2007, 8(7): 519-529.
20. Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation[J]. Science, 2011, 334(6059): 1081-1086.
21. Shin C, Kim JK, Kim JH, et al. Increased cell-free DNA concentrations in patients with obstructive sleep apnea[J]. Psychiatry Clin Neurosci, 2008, 62(6): 721-727.
22. Prasanthi JR, Larson T, Schommer J, et al. Silencing GADD153/ CHOP gene expression protects against Alzheimer's diseaselike pathology induced by 27-hydroxycholesterol in rabbit hippocampus [J]. PLoS One, 2011, 6(10): e26420.
23. Yang JR, Yao FH, Zhang JG, et al. Ischemia-reperfusion induces renal tubule pyroptosis via the CHOP-caspase-11 pathway[J]. Am J Physiol Renal Physiol, 2014, 306(1): F75-F84.
24. Rao RV, Castro-Obregon S, Frankowski H, et al. Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway[J]. J Biol Chem, 2002, 277(24): 21836-21842.
25. Epstein LJ, Kristo D, Strollo PJ Jr, et al. Clinical guideline for the evaluation, management and long-term care of obstructive sleep apnea in adults[J]. J Clin Sleep Med, 2009, 5(3): 263-276.
26. Carlucci A, Ceriana P, Mancini M, et al. Efficacy of bilevel-auto treatment in patients with obstructive sleep apnea not responsive to or intolerant of continuous positive airway pressure ventilation[J]. J Clin Sleep Med, 2015, 11(9): 981-985.
27. Makarenko W, Usatyuk PV, Yuan G, et al. Intermittent hypoxiainduced endothelial barrier dysfunction requires ROS-dependent MAP kinase activation [J]. Am J Physiol Cell Physiol, 2014, 306(8): C745-C752.
28. Gaspar JM, Martins A, Cruz R, et al. Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose[J]. Neuroscience, 2013, 253(12): 380-388.