Tauroursodeoxycholic acid protects retinal neural cells from cell death induced by prolonged exposure to elevated glucose

Neuroscience

Volumn 253, Issue , 2013, Pages 380-388

  Gaspar, J M ^a,b,e   Martins, A ^a   Cruz, R ^a   Rodrigues, C M P ^c   Ambrosio A F ^a,b,d   Santiago, A R ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^d ASSOCIATION FOR INNOVATION AND BIOMEDICAL RESEARCH ON LIGHT AND IMAGE AIBILI   (Portugal)

^e UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

Diabetes; Diabetic retinopathy; Neural apoptosis; Retina; TUDCA

Indexed keywords

APOPTOSIS INDUCING FACTOR; REACTIVE OXYGEN METABOLITE; TAUROURSODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL NUCLEUS; CELL PROTECTION; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYPERGLYCEMIA; MITOCHONDRION; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RETINA DEGENERATION; RETINA NERVE CELL;

2,4-DINITROPHENYLHYDRAZINE; 2′,7′-DICHLORODIHYDROFLUORESCEIN DIACETATE; ADVANCED GLYCATION END PRODUCTS; AGES; AIF; APOPTOSIS-INDUCING FACTOR; BARDET-BIEDL SYNDROME; BBS; DCF; DIABETES; DIABETIC RETINOPATHY; DICHLORODIHYDROFLUORESCEIN; DNPH; DPBS; DULBECCO'S PBS SOLUTION; ECF; EDTA; EGTA; ENHANCED CHEMIFLUORESCENCE; ETHYLENE GLYCOL TETRAACETIC ACID; ETHYLENEDIAMINETETRAACETIC ACID; FITC; FLUORESCEIN ISOTHIOCYANATE; H(2)DCF-DA; NEURAL APOPTOSIS; PHOSPHATIDYLSERINE; PS; REACTIVE OXYGEN SPECIES; RETINA; ROS; SDS; SODIUM DODECYL SULFATE; TAUROURSODEOXYCHOLIC ACID; TERMINAL TRANSFERASE DUTP NICK END LABELING; TUDCA; TUNEL; UDCA; URSODEOXYCHOLIC ACID;

ANIMALS; ANIMALS, NEWBORN; ANNEXIN A5; CELL COUNT; CELL DEATH; CELL NUCLEUS; CELLS, CULTURED; CHOLAGOGUES AND CHOLERETICS; GLUCOSE; IN SITU NICK-END LABELING; MITOCHONDRIA; NEURONS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; RETINA; TAUROCHENODEOXYCHOLIC ACID;

EID: 84885227952     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.08.053     Document Type: Article

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