The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: A new canine model for copper-metabolism disorders

DMM Disease Models and Mechanisms

Volumn 9, Issue 1, 2016, Pages 25-38

  Fieten, Hille ^a   Gill, Yadvinder ^b   Martin, Alan J ^b   Concilli, Mafalda ^c   Dirksen, Karen ^a   Van Steenbeek, Frank G ^a   Spee, Bart ^a   Van Den Ingh, Ted S G A M ^d   Martens, Ellen C C P ^a   Festa, Paola ^c   Chesi, Giancarlo ^c   Van De Sluis, Bart ^e   Houwen, Roderick H J H ^f   Watson, Adrian L ^b   Aulchenko, Yurii S ^g,h   Hodgkinson, Victoria L ^i,j   Zhu, Sha ^i,j   Petris, Michael J ^i,j   Polishchuk, Roman S ^c   Leegwater, Peter A J ^a   Rothuizen, Jan ^a   more..

^a UTRECHT UNIVERSITY   (Netherlands)

^b WALTHAM CENTRE FOR PET NUTRITION   (United Kingdom)

^c TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^d TCCI Consultancy BV   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^g NOVOSIBIRSK STATE UNIVERSITY   (Russian Federation)

^h INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

ⁱ University of Missouri   (United States)

^j UNIVERSITY OF MISSOURI   (United States)

more..

Author keywords

ATP7A; ATP7B; Dog; Liver

Indexed keywords

AMINO ACID; COPPER; MENKES PROTEIN; WILSON DISEASE PROTEIN; ADENOSINE TRIPHOSPHATASE; ATP7A PROTEIN, HUMAN; CATION TRANSPORT PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANINE MODEL; COPPER METABOLISM; COPPER TOXICOSIS; DNA SEQUENCE; ELECTRON TOMOGRAPHY; ENDOPLASMIC RETICULUM; FIBROBLAST; GENETIC ASSOCIATION; GENETIC VARIABILITY; HEPG2 CELL LINE; INTOXICATION; LABRADOR RETRIEVER; MENKES SYNDROME; METABOLIC DISORDER; NONHUMAN; PRIORITY JOURNAL; WILSON DISEASE; AMINO ACID SEQUENCE; ANIMAL; DISEASE MODEL; DOG; FEMALE; GENETIC VARIATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HEP-G2 CELL LINE; HUMAN; LIVER; MALE; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PHENOTYPE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; CATION TRANSPORT PROTEINS; COPPER; DISEASE MODELS, ANIMAL; DOGS; ENDOPLASMIC RETICULUM; FEMALE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HEP G2 CELLS; HEPATOLENTICULAR DEGENERATION; HUMANS; LIVER; MALE; MENKES KINKY HAIR SYNDROME; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84954501057     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.020263     Document Type: Article

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