-
1
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie, T. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA 98, 10869-10874 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
-
2
-
-
83455236666
-
Basal breast cancer: A complex and deadly molecular subtype
-
Bertucci, F., Finetti, P. & Birnbaum, D. Basal breast cancer: a complex and deadly molecular subtype. Curr. Mol. Med. 12, 96-110 (2012).
-
(2012)
Curr. Mol. Med.
, vol.12
, pp. 96-110
-
-
Bertucci, F.1
Finetti, P.2
Birnbaum, D.3
-
3
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas, J. N. & Moon, R. T. WNT signalling pathways as therapeutic targets in cancer. Nat. Rev. Cancer 13, 11-26 (2013).
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
4
-
-
0034636153
-
Beta-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
-
Lin, S. Y. et al. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc. Natl Acad. Sci. USA 97, 4262-4266 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4262-4266
-
-
Lin, S.Y.1
-
5
-
-
0031825010
-
E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma
-
Bukholm, I. K., Nesland, J. M., Karesen, R., Jacobsen, U. & Borresen-Dale, A. L. E-cadherin and alpha-, beta-, and gamma-catenin protein expression in relation to metastasis in human breast carcinoma. J. Pathol. 185, 262-266 (1998).
-
(1998)
J. Pathol.
, vol.185
, pp. 262-266
-
-
Bukholm, I.K.1
Nesland, J.M.2
Karesen, R.3
Jacobsen, U.4
Borresen-Dale, A.L.5
-
6
-
-
77953183234
-
Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome
-
Khramtsov, A. I. et al. Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome. Am. J. Pathol. 176, 2911-2920 (2010).
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 2911-2920
-
-
Khramtsov, A.I.1
-
7
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine wnt-PCP signaling in breast cancer cell migration
-
Luga, V. et al. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 151, 1542-1556 (2012).
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
-
8
-
-
84864956480
-
A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression
-
Anastas, J. N. et al. A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene 31, 3696-3708 (2011).
-
(2011)
Oncogene
, vol.31
, pp. 3696-3708
-
-
Anastas, J.N.1
-
9
-
-
84910066394
-
A noncanonical frizzled2 pathway regulates epithelialmesenchymal transition and metastasis
-
Gujral, T. S. et al. A noncanonical frizzled2 pathway regulates epithelialmesenchymal transition and metastasis. Cell 159, 844-856 (2014).
-
(2014)
Cell
, vol.159
, pp. 844-856
-
-
Gujral, T.S.1
-
10
-
-
58149185543
-
Planar cell polarity signaling: From fly development to human disease
-
Simons, M. & Mlodzik, M. Planar cell polarity signaling: from fly development to human disease. Annu. Rev. Genet. 42, 517-540 (2008).
-
(2008)
Annu. Rev. Genet.
, vol.42
, pp. 517-540
-
-
Simons, M.1
Mlodzik, M.2
-
11
-
-
84908192337
-
Insight into planar cell polarity
-
Sebbagh, M. & Borg, J. P. Insight into planar cell polarity. Exp. Cell Res. 328, 284-295 (2014).
-
(2014)
Exp. Cell Res.
, vol.328
, pp. 284-295
-
-
Sebbagh, M.1
Borg, J.P.2
-
12
-
-
77953498804
-
VANGL2 mutations in human cranial neural-tube defects
-
Lei, Y. P. et al. VANGL2 mutations in human cranial neural-tube defects. N. Engl. J. Med. 362, 2232-2235 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 2232-2235
-
-
Lei, Y.P.1
-
13
-
-
84890453082
-
The 2 faces of JNK signaling in cancer
-
Tournier, C. The 2 faces of JNK signaling in cancer. Genes Cancer 4, 397-400 (2013).
-
(2013)
Genes Cancer
, vol.4
, pp. 397-400
-
-
Tournier, C.1
-
14
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen, T. & Lamark, T. Selective autophagy mediated by autophagic adapter proteins. Autophagy 7, 279-296 (2010).
-
(2010)
Autophagy
, vol.7
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
15
-
-
84923196614
-
SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors
-
Bertrand, M. et al. SQSTM1/p62 regulates the expression of junctional proteins through epithelial-mesenchymal transition factors. Cell Cycle 14, 364-374 (2015).
-
(2015)
Cell Cycle
, vol.14
, pp. 364-374
-
-
Bertrand, M.1
-
16
-
-
66449114033
-
P62 at the crossroads of autophagy, apoptosis, and cancer
-
Moscat, J. & Diaz-Meco, M. T. p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 137, 1001-1004 (2009).
-
(2009)
Cell
, vol.137
, pp. 1001-1004
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
17
-
-
34249789880
-
The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease
-
Rolland, P. et al. The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease. Endocr. Relat. Cancer 14, 73-80 (2007).
-
(2007)
Endocr. Relat. Cancer
, vol.14
, pp. 73-80
-
-
Rolland, P.1
-
18
-
-
41249084239
-
The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis
-
Duran, A. et al. The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis. Cancer Cell 13, 343-354 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 343-354
-
-
Duran, A.1
-
19
-
-
84892941985
-
Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer
-
Luo, R. Z. et al. Accumulation of p62 is associated with poor prognosis in patients with triple-negative breast cancer. Onco. Targets Ther. 6, 883-888 (2013).
-
(2013)
Onco. Targets Ther.
, vol.6
, pp. 883-888
-
-
Luo, R.Z.1
-
20
-
-
84901782394
-
P62/SQSTM1 synergizes with autophagy for tumor growth in vivo
-
Wei, H., Wang, C., Croce, C. M. & Guan, J. L. p62/SQSTM1 synergizes with autophagy for tumor growth in vivo. Genes Dev. 28, 1204-1216 (2014).
-
(2014)
Genes Dev.
, vol.28
, pp. 1204-1216
-
-
Wei, H.1
Wang, C.2
Croce, C.M.3
Guan, J.L.4
-
21
-
-
84867005779
-
Molecular characterisation of endogenous vangl2/vangl1 heteromeric protein complexes
-
Belotti, E. et al. Molecular characterisation of endogenous Vangl2/Vangl1 heteromeric protein complexes. PLoS ONE 7, e46213 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e46213
-
-
Belotti, E.1
-
22
-
-
31044441241
-
Gene expression profiling of breast cell lines identifies potential new basal markers
-
Charafe-Jauffret, E. et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 25, 2273-2284 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 2273-2284
-
-
Charafe-Jauffret, E.1
-
23
-
-
84884398431
-
The human PDZome: A gateway to PDZ mediated functions
-
Belotti, E. et al. The human PDZome: a gateway to PDZ mediated functions. Mol. Cell Proteomics 12, 2587-2603 (2013).
-
(2013)
Mol. Cell Proteomics
, vol.12
, pp. 2587-2603
-
-
Belotti, E.1
-
24
-
-
84869000970
-
Loss of the par3 polarity protein promotes breast tumorigenesis and metastasis
-
McCaffrey, L. M., Montalbano, J., Mihai, C. & Macara, I. G. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell 22, 601-614 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 601-614
-
-
McCaffrey, L.M.1
Montalbano, J.2
Mihai, C.3
Macara, I.G.4
-
25
-
-
34548259958
-
P62/SQSTM1 binds directly to atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv, S. et al. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282, 24131-24145 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
-
26
-
-
0036141525
-
The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos
-
Park, M. & Moon, R. T. The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nat. Cell Biol. 4, 20-25 (2002).
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 20-25
-
-
Park, M.1
Moon, R.T.2
-
27
-
-
0141445968
-
Interaction codes within the family of mammalian phox and bem1p domain-containing proteins
-
Lamark, T. et al. Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins. J. Biol. Chem. 278, 34568-34581 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34568-34581
-
-
Lamark, T.1
-
28
-
-
84866611163
-
Gipc1 has a dual role in vangl2 trafficking and hair bundle integrity in the inner ear
-
Giese, A. P. et al. Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear. Development 139, 3775-3785 (2012).
-
(2012)
Development
, vol.139
, pp. 3775-3785
-
-
Giese, A.P.1
-
29
-
-
0031946369
-
Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62
-
Sanchez, P., De Carcer, G., Sandoval, I. V., Moscat, J. & Diaz-Meco, M. T. Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62. Mol. Cell Biol. 18, 3069-3080 (1998).
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 3069-3080
-
-
Sanchez, P.1
De Carcer, G.2
Sandoval, I.V.3
Moscat, J.4
Diaz-Meco, M.T.5
-
30
-
-
77951231777
-
Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse
-
Gravel, M., Iliescu, A., Horth, C., Apuzzo, S. & Gros, P. Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse. Biochemistry 49, 3445-3455 (2010).
-
(2010)
Biochemistry
, vol.49
, pp. 3445-3455
-
-
Gravel, M.1
Iliescu, A.2
Horth, C.3
Apuzzo, S.4
Gros, P.5
-
31
-
-
0036499966
-
The planar polarity gene strabismus regulates convergent extension movements in xenopus
-
Darken, R. S. et al. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 21, 976-985 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 976-985
-
-
Darken, R.S.1
-
32
-
-
4444239003
-
Paraxial protocadherin coordinates cell polarity during convergent extension via rho A and JNK
-
Unterseher, F. et al. Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK. EMBO J. 23, 3259-3269 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 3259-3269
-
-
Unterseher, F.1
-
33
-
-
34247589181
-
Wnt-5A/ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway
-
Schambony, A. & Wedlich, D. Wnt-5A/Ror2 regulate expression of XPAPC through an alternative noncanonical signaling pathway. Dev. Cell 12, 779-792 (2007).
-
(2007)
Dev. Cell
, vol.12
, pp. 779-792
-
-
Schambony, A.1
Wedlich, D.2
-
34
-
-
84891278007
-
ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program
-
Charafe-Jauffret, E. et al. ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program. Cancer Res. 73, 7290-7300 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 7290-7300
-
-
Charafe-Jauffret, E.1
-
35
-
-
84907553698
-
Vangl1 and vangl2: Planar cell polarity components with a developing role in cancer
-
Hatakeyama, J., Wald, J. H., Printsev, I., Ho, H. Y. & Carraway, 3rd K. L. Vangl1 and Vangl2: planar cell polarity components with a developing role in cancer. Endocr. Relat. Cancer 21, R345-R356 (2014).
-
(2014)
Endocr. Relat. Cancer
, vol.21
, pp. R345-R356
-
-
Hatakeyama, J.1
Wald, J.H.2
Printsev, I.3
Ho, H.Y.4
Carraway, K.L.5
-
36
-
-
84874885773
-
The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration
-
Kaucka, M. et al. The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration. Cancer Res. 73, 1491-1501 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 1491-1501
-
-
Kaucka, M.1
-
37
-
-
84930821197
-
Oncogenic suppression of apoptosis uncovers a rac1/JNK proliferation pathway activated by loss of par3
-
Archibald, A., Mihai, C., Macara, I. G. & McCaffrey, L. Oncogenic suppression of apoptosis uncovers a Rac1/JNK proliferation pathway activated by loss of Par3. Oncogene 34, 3199-3206 (2014).
-
(2014)
Oncogene
, vol.34
, pp. 3199-3206
-
-
Archibald, A.1
Mihai, C.2
Macara, I.G.3
McCaffrey, L.4
-
38
-
-
76649084891
-
Vang-like protein 2 and rac1 interact to regulate adherens junctions
-
Lindqvist, M. et al. Vang-like protein 2 and Rac1 interact to regulate adherens junctions. J. Cell Sci. 123, 472-483 (2010).
-
(2010)
J. Cell Sci.
, vol.123
, pp. 472-483
-
-
Lindqvist, M.1
-
39
-
-
33751274234
-
The JIP family of MAPK scaffold proteins
-
Whitmarsh, A. J. The JIP family of MAPK scaffold proteins. Biochem. Soc. Trans. 34, 828-832 (2006).
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 828-832
-
-
Whitmarsh, A.J.1
-
40
-
-
81055140859
-
The hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi, M. et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell 147, 759-772 (2011).
-
(2011)
Cell
, vol.147
, pp. 759-772
-
-
Cordenonsi, M.1
-
41
-
-
51449094916
-
The frizzled extracellular domain is a ligand for van gogh/stbm during nonautonomous planar cell polarity signaling
-
Wu, J. & Mlodzik, M. The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Dev. Cell 15, 462-469 (2008).
-
(2008)
Dev. Cell
, vol.15
, pp. 462-469
-
-
Wu, J.1
Mlodzik, M.2
-
42
-
-
55549083477
-
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles
-
Devenport, D. & Fuchs, E. Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat. Cell Biol. 10, 1257-1268 (2008).
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1257-1268
-
-
Devenport, D.1
Fuchs, E.2
-
43
-
-
84874284008
-
Spatial coupling of JNK activation to the B cell antigen receptor by tyrosinephosphorylated ezrin
-
Parameswaran, N., Enyindah-Asonye, G., Bagheri, N., Shah, N. B. & Gupta, N. Spatial coupling of JNK activation to the B cell antigen receptor by tyrosinephosphorylated ezrin. J. Immunol. 190, 2017-2026 (2013).
-
(2013)
J. Immunol.
, vol.190
, pp. 2017-2026
-
-
Parameswaran, N.1
Enyindah-Asonye, G.2
Bagheri, N.3
Shah, N.B.4
Gupta, N.5
-
44
-
-
80053586265
-
P62 is a key regulator of nutrient sensing in the mTORC1 pathway
-
Duran, A. et al. p62 is a key regulator of nutrient sensing in the mTORC1 pathway. Mol. Cell 44, 134-146 (2011).
-
(2011)
Mol. Cell
, vol.44
, pp. 134-146
-
-
Duran, A.1
-
45
-
-
84890284499
-
JNK signalling in cancer: In need of new, smarter therapeutic targets
-
Bubici, C. & Papa, S. JNK signalling in cancer: in need of new, smarter therapeutic targets. Br. J. Pharmacol. 171, 24-37 (2014).
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 24-37
-
-
Bubici, C.1
Papa, S.2
-
46
-
-
84865804353
-
Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells
-
Yunokawa, M. et al. Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells. Cancer Sci. 103, 1665-1671 (2012).
-
(2012)
Cancer Sci.
, vol.103
, pp. 1665-1671
-
-
Yunokawa, M.1
-
47
-
-
84899057121
-
Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer
-
Singh, J. et al. Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer. Breast Cancer Res. 16, R32 (2014).
-
(2014)
Breast Cancer Res.
, vol.16
, pp. R32
-
-
Singh, J.1
-
48
-
-
84927934073
-
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells
-
Wang, Z. et al. Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells. Cell Death Dis. 5, e1563 (2014).
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1563
-
-
Wang, Z.1
-
49
-
-
74349119441
-
Distinct xenopus nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the wnt/PCP pathway
-
Luxardi, G., Marchal, L., Thome, V. & Kodjabachian, L. Distinct Xenopus Nodal ligands sequentially induce mesendoderm and control gastrulation movements in parallel to the Wnt/PCP pathway. Development 137, 417-426 (2010).
-
(2010)
Development
, vol.137
, pp. 417-426
-
-
Luxardi, G.1
Marchal, L.2
Thome, V.3
Kodjabachian, L.4
-
50
-
-
0142121516
-
Exploration, normalization, and summaries of high density oligonucleotide array probe level data
-
Irizarry, R. A. et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4, 249-264 (2003).
-
(2003)
Biostatistics
, vol.4
, pp. 249-264
-
-
Irizarry, R.A.1
-
51
-
-
62449131093
-
Supervised risk predictor of breast cancer based on intrinsic subtypes
-
Parker, J. S. et al. Supervised risk predictor of breast cancer based on intrinsic subtypes. J. Clin. Oncol. 27, 1160-1167 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1160-1167
-
-
Parker, J.S.1
-
52
-
-
81155131661
-
Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer
-
Sabatier, R. et al. Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer. PLoS ONE 6, e27656 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e27656
-
-
Sabatier, R.1
-
53
-
-
37549006702
-
Integrated profiling of basal and luminal breast cancers
-
Adelaide, J. et al. Integrated profiling of basal and luminal breast cancers. Cancer Res. 67, 11565-11575 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 11565-11575
-
-
Adelaide, J.1
-
54
-
-
33750310901
-
REporting recommendations for tumor MARKer prognostic studies (REMARK)
-
McShane, L. M. et al. REporting recommendations for tumor MARKer prognostic studies (REMARK). Breast Cancer Res. Treat. 100, 229-235 (2006).
-
(2006)
Breast Cancer Res. Treat.
, vol.100
, pp. 229-235
-
-
McShane, L.M.1
-
55
-
-
29144469472
-
The mammalian scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin
-
Qin, Y., Capaldo, C., Gumbiner, B. M. & Macara, I. G. The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J. Cell Biol. 171, 1061-1071 (2005).
-
(2005)
J. Cell Biol.
, vol.171
, pp. 1061-1071
-
-
Qin, Y.1
Capaldo, C.2
Gumbiner, B.M.3
Macara, I.G.4
-
56
-
-
2642547462
-
Mammalian scribble forms a tight complex with the betaPIX exchange factor
-
Audebert, S. et al. Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr. Biol. 14, 987-995 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 987-995
-
-
Audebert, S.1
|