Molecular Characterisation of Endogenous Vangl2/Vangl1 Heteromeric Protein Complexes

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Belotti, Edwige ^a,b,c   Puvirajesinghe, Tania M ^a,b,c   Audebert, Stéphane ^a,b,c   Baudelet, Emilie ^a,b,c   Camoin, Luc ^a,b,c   Pierres, Michel ^d   Lasvaux, Lea ^e   Ferracci, Géraldine ^f   Montcouquiol, Mireille ^e   Borg, Jean Paul ^a,b,c  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^e UNIVERSITÉ DE BORDEAUX   (France)

^f University of Mediterranée   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; GLUTATHIONE TRANSFERASE; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; VANGL1 PROTEIN; VANGL2 PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY AFFINITY; ANTIBODY SPECIFICITY; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL POLARITY; COCHLEA; COMPLEX FORMATION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; HETEROZYGOSITY; HOMOZYGOSITY; IMMUNOPRECIPITATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; SURFACE PLASMON RESONANCE; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; CELL POLARITY; GENE EXPRESSION; HETEROZYGOTE; HOMOZYGOTE; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURAL TUBE DEFECTS; POINT MUTATION; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEOMICS; SURFACE PLASMON RESONANCE;

MUS;

EID: 84867005779     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046213     Document Type: Article

References (30)

1. Doudney K, Ybot-Gonzalez P, Paternotte C, Stevenson RE, Greene ND, et al. (2005) Analysis of the planar cell polarity gene Vangl2 and its co-expressed paralogue Vangl1 in neural tube defect patients. Am J Med Genet A 136: 90-92.
2. Murdoch JN, Doudney K, Paternotte C, Copp AJ, Stanier P, (2001) Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum Mol Genet 10: 2593-2601.
3. Park M, Moon RT, (2002) The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos. Nat Cell Biol 4: 20-25.
4. Copp AJ, Greene ND, Murdoch JN, (2003) The genetic basis of mammalian neurulation. Nat Rev Genet 4: 784-793.
5. Lake BB, Sokol SY, (2009) Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain. J Cell Biol 185: 59-66.
6. Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, et al. (2003) Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature 423: 173-177.
7. Taylor J, Abramova N, Charlton J, Adler PN, (1998) Van Gogh: a new Drosophila tissue polarity gene. Genetics 150: 199-210.
8. Wolff T, Rubin GM, (1998) Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila. Development 125: 1149-1159.
9. Torban E, Kor C, Gros P, (2004) Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates. Trends Genet 20: 570-577.
10. Jessen JR, Solnica-Krezel L, (2004) Identification and developmental expression pattern of van gogh-like 1, a second zebrafish strabismus homologue. Gene Expr Patterns 4: 339-344.
11. Lei YP, Zhang T, Li H, Wu BL, Jin L, et al. (2010) VANGL2 mutations in human cranial neural-tube defects. N Engl J Med 362: 2232-2235.
12. Kibar Z, Torban E, McDearmid JR, Reynolds A, Berghout J, et al. (2007) Mutations in VANGL1 associated with neural-tube defects. N Engl J Med 356: 1432-1437.
13. Kibar Z, Vogan KJ, Groulx N, Justice MJ, Underhill DA, et al. (2001) Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet 28: 251-255.
14. Gravel M, Iliescu A, Horth C, Apuzzo S, Gros P, (2010) Molecular and cellular mechanisms underlying neural tube defects in the loop-tail mutant mouse. Biochemistry 49: 3445-3455.
15. Iliescu A, Gravel M, Horth C, Apuzzo S, Gros P, (2011) Transmembrane topology of mammalian planar cell polarity protein Vangl1. Biochemistry 50: 2274-2282.
16. Torban E, Wang HJ, Groulx N, Gros P, (2004) Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family. J Biol Chem 279: 52703-52713.
17. Torban E, Patenaude AM, Leclerc S, Rakowiecki S, Gauthier S, et al. (2008) Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A 105: 3449-3454.
18. Tissir F, Goffinet AM, (2006) Expression of planar cell polarity genes during development of the mouse CNS. Eur J Neurosci 23: 597-607.
19. Song H, Hu J, Chen W, Elliott G, Andre P, et al. (2010) Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature 466: 378-382.
20. Yin H, Copley CO, Goodrich LV, Deans MR, (2012) Comparison of Phenotypes between Different vangl2 Mutants Demonstrates Dominant Effects of the Looptail Mutation during Hair Cell Development. PLoS One 7: e31988.
21. Montcouquiol M, Sans N, Huss D, Kach J, Dickman JD, et al. (2006) Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals. J Neurosci 26: 5265-5275.
22. Gao B, Song H, Bishop K, Elliot G, Garrett L, et al. (2011) Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Dev Cell 20: 163-176.
23. Ivanov IP, Firth AE, Michel AM, Atkins JF, Baranov PV, (2011) Identification of evolutionarily conserved non-AUG-initiated N-terminal extensions in human coding sequences. Nucleic Acids Res 39: 4220-4234.
24. Torban E, Wang HJ, Patenaude AM, Riccomagno M, Daniels E, et al. (2007) Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation. Gene Expr Patterns 7: 346-354.
25. Merte J, Jensen D, Wright K, Sarsfield S, Wang Y, et al. (2010) Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol 12: 41-46; sup pp 41-48.
26. Wansleeben C, Feitsma H, Montcouquiol M, Kroon C, Cuppen E, et al. (2010) Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. Development 137: 1067-1073.
27. Devenport D, Fuchs E, (2008) Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol 10: 1257-1268.
28. Wu J, Mlodzik M, (2008) The frizzled extracellular domain is a ligand for Van Gogh/Stbm during nonautonomous planar cell polarity signaling. Dev Cell 15: 462-469.
29. Berditchevski F, Odintsova E, (2007) Tetraspanins as regulators of protein trafficking. Traffic 8: 89-96.
30. Audebert S, Navarro C, Nourry C, Chasserot-Golaz S, Lecine P, et al. (2004) Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr Biol 14: 987-995.