메뉴 건너뛰기




Volumn 27, Issue 1, 2016, Pages 305-313

Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden

Author keywords

[No Author keywords available]

Indexed keywords

TRIMETHYLAMINE OXIDE; METHYLAMINE; TRIMETHYLOXAMINE;

EID: 84954450626     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2014111063     Document Type: Article
Times cited : (336)

References (39)
  • 1
    • 81455126813 scopus 로고    scopus 로고
    • Bethesda MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases
    • US Renal Data System: USRDS 2013 Annual Report, Bethesda, MD, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2013
    • (2013) USRDS 2013 Annual Report
  • 2
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296-1305, 2004
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.Y.5
  • 3
    • 0032229826 scopus 로고    scopus 로고
    • Epidemiology of cardiovascular disease in chronic renal disease
    • Foley RN, Parfrey PS, Sarnak MJ: Epidemiology of cardiovascular disease in chronic renal disease. J Am Soc Nephrol 9[Suppl]: S16-S23, 1998
    • (1998) J Am Soc Nephrol , vol.9 , pp. 16-23
    • Foley, R.N.1    Parfrey, P.S.2    Sarnak, M.J.3
  • 6
    • 31644438457 scopus 로고    scopus 로고
    • Cardiovascular risk factors in chronic kidney disease
    • Menon V, Gul A, Sarnak MJ: Cardiovascular risk factors in chronic kidney disease. Kidney Int 68: 1413-1418, 2005
    • (2005) Kidney Int , vol.68 , pp. 1413-1418
    • Menon, V.1    Gul, A.2    Sarnak, M.J.3
  • 7
    • 0141468244 scopus 로고    scopus 로고
    • American heart associationcouncils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention
    • Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association councils on kidney in cardiovascular disease, high blood pressure research, clinical cardiology, and epidemiology and prevention
    • SarnakMJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, HammLL, McCullough PA, Kasiske BL, Kelepouris E, Klag MJ, Parfrey P, Pfeffer M, Raij L, SpinosaDJ, Wilson PW; AmericanHeart AssociationCouncils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention: Kidney disease as a risk factor for development of cardiovascular disease: A statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation 108: 2154-2169, 2003
    • (2003) Circulation , vol.108 , pp. 2154-2169
    • Sarnak, M.J.1    Levey, A.S.2    Schoolwerth, A.C.3    Coresh, J.4    Culleton, B.5    Hamm, L.L.6    McCullough, P.A.7    Kasiske, B.L.8    Kelepouris, E.9    Klag, M.J.10    Parfrey, P.11    Pfeffer, M.12    Raij, L.13    Spinosa, D.J.14    Wilson, P.W.15
  • 12
    • 0032531915 scopus 로고    scopus 로고
    • Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: Selective catalysis by FMO3
    • LangDH, YeungCK, Peter RM, IbarraC,Gasser R, Itagaki K, PhilpotRM, Rettie AE: Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: Selective catalysis by FMO3. Biochem Pharmacol 56: 1005-1012, 1998
    • (1998) Biochem Pharmacol , vol.56 , pp. 1005-1012
    • Lang, D.H.1    Yeung, C.K.2    Peter, R.M.3    Ibarra, C.4    Gasser, R.5    Itagaki, K.6    Philpot, R.M.7    Rettie, A.E.8
  • 13
    • 0023160321 scopus 로고
    • The metabolism of 14C-labelled trimethylamine and its N-oxide in man
    • Al-Waiz M, Mitchell SC, Idle JR, Smith RL: The metabolism of 14C-labelled trimethylamine and its N-oxide in man. Xenobiotica 17: 551-558, 1987
    • (1987) Xenobiotica , vol.17 , pp. 551-558
    • Al-Waiz, M.1    Mitchell, S.C.2    Idle, J.R.3    Smith, R.L.4
  • 14
    • 0030608897 scopus 로고    scopus 로고
    • Metabolic disposition of [14C]-trimethylamine N-oxide in rat: Variation with dose and route of administration
    • Mitchell SC, Zhang AQ, Noblet JM, Gillespie S, Jones N, Smith RL: Metabolic disposition of [14C]-trimethylamine N-oxide in rat: Variation with dose and route of administration. Xenobiotica 27: 1187-1197, 1997
    • (1997) Xenobiotica , vol.27 , pp. 1187-1197
    • Mitchell, S.C.1    Zhang, A.Q.2    Noblet, J.M.3    Gillespie, S.4    Jones, N.5    Smith, R.L.6
  • 15
    • 33646205972 scopus 로고    scopus 로고
    • Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis
    • Bain MA, Faull R, Fornasini G, Milne RW, Evans AM: Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis. NephrolDial Transplant 21: 1300-1304, 2006
    • (2006) NephrolDial Transplant , vol.21 , pp. 1300-1304
    • Bain, M.A.1    Faull, R.2    Fornasini, G.3    Milne, R.W.4    Evans, A.M.5
  • 17
    • 84925862053 scopus 로고    scopus 로고
    • Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease
    • Tang WH, Wang Z, Kennedy DJ, Wu Y, Buffa JA, Agatisa-Boyle B, Li XS, Levison BS, Hazen SL: Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease. Circ Res 116: 448-455, 2015
    • (2015) Circ Res , vol.116 , pp. 448-455
    • Tang, W.H.1    Wang, Z.2    Kennedy, D.J.3    Wu, Y.4    Buffa, J.A.5    Agatisa-Boyle, B.6    Li, X.S.7    Levison, B.S.8    Hazen, S.L.9
  • 18
    • 48649107955 scopus 로고    scopus 로고
    • Low adiponectin levels are associated with atherogenic dyslipidemia and lipid-rich plaque in nondiabetic coronary arteries
    • Marso SP,Mehta SK, Frutkin A, House JA,McCrary JR, Kulkarni KR: Low adiponectin levels are associated with atherogenic dyslipidemia and lipid-rich plaque in nondiabetic coronary arteries. Diabetes Care 31: 989-994, 2008
    • (2008) Diabetes Care , vol.31 , pp. 989-994
    • Marso, S.P.1    Mehta, S.K.2    Frutkin, A.3    House, J.A.4    McCrary, J.R.5    Kulkarni, K.R.6
  • 19
    • 77349115070 scopus 로고    scopus 로고
    • Diabetes duration is associated with increased thin-cap fibroatheroma detected by intravascular ultrasound with virtual histology
    • Lindsey JB, House JA, Kennedy KF, Marso SP: Diabetes duration is associated with increased thin-cap fibroatheroma detected by intravascular ultrasound with virtual histology. Circ Cardiovasc Interv 2: 543-548, 2009
    • (2009) Circ Cardiovasc Interv , vol.2 , pp. 543-548
    • Lindsey, J.B.1    House, J.A.2    Kennedy, K.F.3    Marso, S.P.4
  • 20
    • 84901444529 scopus 로고    scopus 로고
    • The gutmicrobiome, kidney disease, and targeted interventions
    • Ramezani A, Raj DS: The gutmicrobiome, kidney disease, and targeted interventions. J Am Soc Nephrol 25: 657-670, 2014
    • (2014) J Am Soc Nephrol , vol.25 , pp. 657-670
    • Ramezani, A.1    Raj, D.S.2
  • 22
    • 0029834566 scopus 로고    scopus 로고
    • Inhibition of the accumulation of uremic toxins in the blood and their precursors in the feces after oral administration of Lebenin, a lactic acid bacteria preparation, to uremic patients undergoing hemodialysis
    • Hida M, Aiba Y, Sawamura S, Suzuki N, Satoh T, Koga Y: Inhibition of the accumulation of uremic toxins in the blood and their precursors in the feces after oral administration of Lebenin, a lactic acid bacteria preparation, to uremic patients undergoing hemodialysis. Nephron 74: 349-355, 1996
    • (1996) Nephron , vol.74 , pp. 349-355
    • Hida, M.1    Aiba, Y.2    Sawamura, S.3    Suzuki, N.4    Satoh, T.5    Koga, Y.6
  • 23
    • 84880436588 scopus 로고    scopus 로고
    • Chronic kidney disease causes disruption of gastric and small intestinal epithelial tight junction
    • Vaziri ND, Yuan J, Nazertehrani S, Ni Z, Liu S: Chronic kidney disease causes disruption of gastric and small intestinal epithelial tight junction. Am J Nephrol 38: 99-103, 2013
    • (2013) Am J Nephrol , vol.38 , pp. 99-103
    • Vaziri, N.D.1    Yuan, J.2    Nazertehrani, S.3    Ni, Z.4    Liu, S.5
  • 24
    • 0025147015 scopus 로고
    • Increased intestinal permeability to differently sized polyethylene glycols in uremic rats: Effects of low-and high-protein diets
    • Magnusson M, Magnusson KE, Sundqvist T, Denneberg T: Increased intestinal permeability to differently sized polyethylene glycols in uremic rats: Effects of low-and high-protein diets. Nephron 56: 306-311, 1990
    • (1990) Nephron , vol.56 , pp. 306-311
    • Magnusson, M.1    Magnusson, K.E.2    Sundqvist, T.3    Denneberg, T.4
  • 25
    • 0025899472 scopus 로고
    • Impaired intestinal barrier function measured by differently sized polyethylene glycols in patients with chronic renal failure
    • Magnusson M, Magnusson KE, Sundqvist T, Denneberg T: Impaired intestinal barrier function measured by differently sized polyethylene glycols in patients with chronic renal failure. Gut 32: 754-759, 1991
    • (1991) Gut , vol.32 , pp. 754-759
    • Magnusson, M.1    Magnusson, K.E.2    Sundqvist, T.3    Denneberg, T.4
  • 27
    • 0033518231 scopus 로고    scopus 로고
    • Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant
    • Wolfe RA, Ashby VB,Milford EL,Ojo AO, Ettenger RE,Agodoa LY,Held PJ, Port FK: Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl JMed 341: 1725-1730, 1999
    • (1999) N Engl JMed , vol.341 , pp. 1725-1730
    • Wolfe, R.A.1    Ashby, V.B.2    Milford, E.3    Lojo, A.O.4    Ettenger, R.E.5    Agodoa, L.Y.6    Held, P.J.7    Port, F.K.8
  • 28
    • 0027305120 scopus 로고
    • Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients
    • Port FK, Wolfe RA, Mauger EA, Berling DP, Jiang K: Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients. JAMA 270: 1339-1343, 1993
    • (1993) JAMA , vol.270 , pp. 1339-1343
    • Port, F.K.1    Wolfe, R.A.2    Mauger, E.A.3    Berling, D.P.4    Jiang, K.5
  • 30
    • 27744550473 scopus 로고    scopus 로고
    • Aberrant activation of the TNF-alpha system and production of Fas and scavenger receptors on monocytes in patients with end-stage renal disease
    • Wu CC, Chen JS, Lin SH, Chu P, Lin YF, Lin SM, Liao TN: Aberrant activation of the TNF-alpha system and production of Fas and scavenger receptors on monocytes in patients with end-stage renal disease. Artif Organs 29: 701-707, 2005
    • (2005) Artif Organs , vol.29 , pp. 701-707
    • Wu, C.C.1    Chen, J.S.2    Lin, S.H.3    Chu, P.4    Lin, Y.F.5    Lin, S.M.6    Liao, T.N.7
  • 31
    • 0030004558 scopus 로고    scopus 로고
    • Enhanced scavenger receptor expression in monocyte-macrophages in dialysis patients
    • Ando M, Lundkvist I, Bergström J, Lindholm B: Enhanced scavenger receptor expression in monocyte-macrophages in dialysis patients. Kidney Int 49: 773-780, 1996
    • (1996) Kidney Int , vol.49 , pp. 773-780
    • Ando, M.1    Lundkvist, I.2    Bergström, J.3    Lindholm, B.4
  • 32
    • 0030887030 scopus 로고    scopus 로고
    • Uremic serumenhances scavenger receptor expression and activity in the human monocytic cell line U937
    • Ando M, Gåfvels M, Bergström J, Lindholm B, Lundkvist I: Uremic serumenhances scavenger receptor expression and activity in the human monocytic cell line U937. Kidney Int 51: 785-792, 1997
    • (1997) Kidney Int , vol.51 , pp. 785-792
    • Ando, M.1    Gåfvels, M.2    Bergström, J.3    Lindholm, B.4    Lundkvist, I.5
  • 37
    • 85190346601 scopus 로고    scopus 로고
    • Accessed September 2nd
    • St. Luke's Mid America Heart Institute Imaging Core Laboratory website. http://www.saintlukeshealthsystem.org/imaging-core-lab-research-studies. Accessed September 2nd, 2014
    • (2014)
  • 38
    • 0020701346 scopus 로고
    • A more meaningful scoring system for determining the severity of coronary heart disease
    • Gensini GG: A more meaningful scoring system for determining the severity of coronary heart disease. Am J Cardiol 51: 606, 1983
    • (1983) Am J Cardiol , vol.51 , pp. 606
    • Gensini, G.G.1
  • 39
    • 84924411408 scopus 로고    scopus 로고
    • Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine
    • Ocque AJ, Stubbs JR, Nolin TD: Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine. J Pharm Biomed Anal 109: 128-135, 2015
    • (2015) J Pharm Biomed Anal , vol.109 , pp. 128-135
    • Ocque, A.J.1    Stubbs, J.R.2    Nolin, T.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.