Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine

Journal of Pharmaceutical and Biomedical Analysis

Volumn 109, Issue , 2015, Pages 128-135

  Ocque, Andrew J ^a   Stubbs, Jason R ^b   Nolin, Thomas D ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Choline; Human plasma; Human urine; LC MS MS; Trimethylamine N oxide

Indexed keywords

BETAINE; CHOLINE; TRIMETHYLAMINE OXIDE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; METHYLAMINE; TRIMETHYLOXAMINE;

ACCURACY; ARTICLE; ATHEROSCLEROSIS; BLOOD LEVEL; CHROMATOGRAPHY; ELECTROSPRAY; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY DISEASE; KIDNEY TRANSPLANTATION; PLASMA; PRIORITY JOURNAL; QUALITY CONTROL; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; URINE; BLOOD; CALIBRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PILOT STUDY; REPRODUCIBILITY; STANDARD;

BETAINE; CALIBRATION; CHOLINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; INDICATORS AND REAGENTS; KIDNEY DISEASES; MASS SPECTROMETRY; METHYLAMINES; PILOT PROJECTS; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 84924411408     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2015.02.040     Document Type: Article

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