메뉴 건너뛰기




Volumn 146, Issue 4, 2015, Pages 607-617

System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis

Author keywords

2 (methylamino)isobutyric acid; Amino acid transporter; Arthritis; Glutamine; Sodium coupled neutral amino acid transporter

Indexed keywords

2 METHYL 2 METHYLAMINOPROPIONIC ACID; AMINO ACID TRANSPORTER; ARALKYLAMINE ACETYLTRANSFERASE; GLUTAMINE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 3; SNAT1 PROTEIN; SNAT2 PROTEIN; UNCLASSIFIED DRUG; ANTIBODY; COLLAGEN; NITRIC OXIDE; SLC38A1 PROTEIN, MOUSE; SLC38A2 PROTEIN, MOUSE; SODIUM;

EID: 84954424736     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12531     Document Type: Article
Times cited : (17)

References (61)
  • 1
    • 0020282952 scopus 로고
    • Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat
    • Ardawi MSM, Newsholme EA. Maximum activities of some enzymes of glycolysis, the tricarboxylic acid cycle and ketone-body and glutamine utilization pathways in lymphocytes of the rat. Biochem J 1982; 208:743-8.
    • (1982) Biochem J , vol.208 , pp. 743-748
    • Ardawi, M.S.M.1    Newsholme, E.A.2
  • 2
    • 0020617998 scopus 로고
    • Glutamine metabolism in lymphocytes of the rat
    • Ardawi MS, Newsholme EA. Glutamine metabolism in lymphocytes of the rat. Biochem J 1983; 212:835-42.
    • (1983) Biochem J , vol.212 , pp. 835-842
    • Ardawi, M.S.1    Newsholme, E.A.2
  • 3
    • 0024333206 scopus 로고
    • Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture
    • Newsholme P, Newsholme EA. Rates of utilization of glucose, glutamine and oleate and formation of end-products by mouse peritoneal macrophages in culture. Biochem J 1989; 261:211-8.
    • (1989) Biochem J , vol.261 , pp. 211-218
    • Newsholme, P.1    Newsholme, E.A.2
  • 5
    • 0015044023 scopus 로고
    • The rapid induction by phytohemagglutinin of increased α-aminoisobutyric acid uptake by lymphocytes
    • Mendelsohn J, Skinner A, Kornfeld S. The rapid induction by phytohemagglutinin of increased α-aminoisobutyric acid uptake by lymphocytes. J Clin Investig 1971; 50:818-26.
    • (1971) J Clin Investig , vol.50 , pp. 818-826
    • Mendelsohn, J.1    Skinner, A.2    Kornfeld, S.3
  • 6
    • 0015923719 scopus 로고
    • Selective early activation of a sodium dependent amino acid transport system in stimulated rat lymphocytes
    • van den Berg KJ, Betel I. Selective early activation of a sodium dependent amino acid transport system in stimulated rat lymphocytes. FEBS Lett 1973; 29:149-52.
    • (1973) FEBS Lett , vol.29 , pp. 149-152
    • van den Berg, K.J.1    Betel, I.2
  • 7
    • 0015541397 scopus 로고
    • Increased transport of 2-aminoisobutyric acid in rat lymphocytes stimulated with concanavalin A
    • Berg KJVD, Betel I. Increased transport of 2-aminoisobutyric acid in rat lymphocytes stimulated with concanavalin A. Exp Cell Res 1973; 76:63-72.
    • (1973) Exp Cell Res , vol.76 , pp. 63-72
    • Berg, K.J.V.D.1    Betel, I.2
  • 8
    • 0015977545 scopus 로고
    • Correlation of early changes in amino acid transport and DNA synthesis in stimulated lymphocytes
    • van den Berg KJ, Betel I. Correlation of early changes in amino acid transport and DNA synthesis in stimulated lymphocytes. Cell Immunol 1974; 10:319-23.
    • (1974) Cell Immunol , vol.10 , pp. 319-323
    • van den Berg, K.J.1    Betel, I.2
  • 9
    • 0018251579 scopus 로고
    • Amino acid transport in thymic- and spleen-derived lymphocytes
    • Wise WC. Amino acid transport in thymic- and spleen-derived lymphocytes. J Cell Physiol 1978; 97:161-7.
    • (1978) J Cell Physiol , vol.97 , pp. 161-167
    • Wise, W.C.1
  • 10
    • 0018290939 scopus 로고
    • Enhanced stability of the Na-dependent amino acid-transport system after lymphocyte activation
    • Borghetti AF, Kay JE. Enhanced stability of the Na-dependent amino acid-transport system after lymphocyte activation. Biochem J 1979; 182:237-9.
    • (1979) Biochem J , vol.182 , pp. 237-239
    • Borghetti, A.F.1    Kay, J.E.2
  • 11
    • 1242317638 scopus 로고    scopus 로고
    • Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family
    • Mackenzie BB, Erickson JDJ. Sodium-coupled neutral amino acid (System N/A) transporters of the SLC38 gene family. Pflugers Arch 2004; 447:784-95.
    • (2004) Pflugers Arch , vol.447 , pp. 784-795
    • Mackenzie, B.B.1    Erickson, J.D.J.2
  • 12
    • 77955475969 scopus 로고    scopus 로고
    • Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation
    • Carr EL, Kelman A, Wu GS, Gopaul R, Senkevitch E, Aghvanyan A et al. Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. J Immunol 2010; 185:1037-44.
    • (2010) J Immunol , vol.185 , pp. 1037-1044
    • Carr, E.L.1    Kelman, A.2    Wu, G.S.3    Gopaul, R.4    Senkevitch, E.5    Aghvanyan, A.6
  • 13
    • 84876514626 scopus 로고    scopus 로고
    • Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation
    • Sinclair LV, Rolf J, Emslie E, Shi Y-B, Taylor PM, Cantrell DA. Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation. Nat Immunol 2013; 14:500-8.
    • (2013) Nat Immunol , vol.14 , pp. 500-508
    • Sinclair, L.V.1    Rolf, J.2    Emslie, E.3    Shi, Y.-B.4    Taylor, P.M.5    Cantrell, D.A.6
  • 14
    • 84255199079 scopus 로고    scopus 로고
    • The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
    • Wang R, Dillon CP, Shi LZ, Milasta S, Carter R, Finkelstein D et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 2011; 35:871-82.
    • (2011) Immunity , vol.35 , pp. 871-882
    • Wang, R.1    Dillon, C.P.2    Shi, L.Z.3    Milasta, S.4    Carter, R.5    Finkelstein, D.6
  • 15
    • 0001594597 scopus 로고
    • The use of N-methylation to direct the route of mediated transport of amino acids
    • Christensen HN, Oxender DL, Liang M, Vatz KA. The use of N-methylation to direct the route of mediated transport of amino acids. J Biol Chem 1965; 240:3609-16.
    • (1965) J Biol Chem , vol.240 , pp. 3609-3616
    • Christensen, H.N.1    Oxender, D.L.2    Liang, M.3    Vatz, K.A.4
  • 16
    • 33847364776 scopus 로고    scopus 로고
    • Fragmentation of two quantitative trait loci controlling collagen-induced arthritis reveals a new set of interacting subloci
    • Ahlqvist E, Bockermann R, Holmdahl R. Fragmentation of two quantitative trait loci controlling collagen-induced arthritis reveals a new set of interacting subloci. J Immunol 2007; 178:3084-90.
    • (2007) J Immunol , vol.178 , pp. 3084-3090
    • Ahlqvist, E.1    Bockermann, R.2    Holmdahl, R.3
  • 17
    • 0022656277 scopus 로고
    • Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies
    • Holmdahl R, Rubin K, Klareskog L, Larsson E, Wigzell H. Characterization of the antibody response in mice with type II collagen-induced arthritis, using monoclonal anti-type II collagen antibodies. Arthritis Rheum 1986; 29:400-10.
    • (1986) Arthritis Rheum , vol.29 , pp. 400-410
    • Holmdahl, R.1    Rubin, K.2    Klareskog, L.3    Larsson, E.4    Wigzell, H.5
  • 18
    • 33645736561 scopus 로고    scopus 로고
    • Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen
    • Bajtner E, Nandakumar KS, Engström Å, Holmdahl R. Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen. Arthritis Res Ther 2005; 7:R1148-57.
    • (2005) Arthritis Res Ther , vol.7 , pp. R1148-R1157
    • Bajtner, E.1    Nandakumar, K.S.2    Engström, A.3    Holmdahl, R.4
  • 20
    • 0031903794 scopus 로고    scopus 로고
    • Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis
    • Corthay A, Bäcklund J, Broddefalk J, Michaëlsson E, Goldschmidt TJ, Kihlberg J et al. Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis. Eur J Immunol 1998; 28:2580-90.
    • (1998) Eur J Immunol , vol.28 , pp. 2580-2590
    • Corthay, A.1    Bäcklund, J.2    Broddefalk, J.3    Michaëlsson, E.4    Goldschmidt, T.J.5    Kihlberg, J.6
  • 21
    • 0018288451 scopus 로고
    • Enhanced transport of natural amino acids after activation of pig lymphocytes
    • Borghetti AF, Kay JE, Wheeler KP. Enhanced transport of natural amino acids after activation of pig lymphocytes. Biochem J 1979; 182:27-32.
    • (1979) Biochem J , vol.182 , pp. 27-32
    • Borghetti, A.F.1    Kay, J.E.2    Wheeler, K.P.3
  • 22
    • 0021824122 scopus 로고
    • Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism
    • Brand K. Glutamine and glucose metabolism during thymocyte proliferation. Pathways of glutamine and glutamate metabolism. Biochem J 1985; 228:353-61.
    • (1985) Biochem J , vol.228 , pp. 353-361
    • Brand, K.1
  • 23
    • 0037908675 scopus 로고    scopus 로고
    • Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling
    • Gu S, Langlais P, Liu F, Jiang JX. Mouse system-N amino acid transporter, mNAT3, expressed in hepatocytes and regulated by insulin-activated and phosphoinositide 3-kinase-dependent signalling. Biochem J 2003; 371(Pt 3):721-31.
    • (2003) Biochem J , vol.371 , Issue.Pt 3 , pp. 721-731
    • Gu, S.1    Langlais, P.2    Liu, F.3    Jiang, J.X.4
  • 24
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006; 124:471-84.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 25
    • 0029797129 scopus 로고    scopus 로고
    • Glutamine, lymphocyte proliferation and cytokine production
    • Rohde T, MacLean DA, Pedersen BK. Glutamine, lymphocyte proliferation and cytokine production. Scand J Immunol 1996; 44:648-50.
    • (1996) Scand J Immunol , vol.44 , pp. 648-650
    • Rohde, T.1    MacLean, D.A.2    Pedersen, B.K.3
  • 26
    • 0030745596 scopus 로고    scopus 로고
    • Glutamine requirement of proliferating T lymphocytes
    • Yaqoob P, Calder PC. Glutamine requirement of proliferating T lymphocytes. Nutrition 1997; 13:646-51.
    • (1997) Nutrition , vol.13 , pp. 646-651
    • Yaqoob, P.1    Calder, P.C.2
  • 27
    • 0032192268 scopus 로고    scopus 로고
    • Cytokine production by human peripheral blood mononuclear cells - differential sensitivity to glutamine availability
    • Yaqoob P, Calder PC. Cytokine production by human peripheral blood mononuclear cells - differential sensitivity to glutamine availability. Cytokine 1998; 10:790-4.
    • (1998) Cytokine , vol.10 , pp. 790-794
    • Yaqoob, P.1    Calder, P.C.2
  • 28
    • 0031569363 scopus 로고    scopus 로고
    • Hyperosmotic stress as a stimulant for proinflammatory cytokine production
    • Shapiro L, Dinarello CA. Hyperosmotic stress as a stimulant for proinflammatory cytokine production. Exp Cell Res 1997; 231:354-62.
    • (1997) Exp Cell Res , vol.231 , pp. 354-362
    • Shapiro, L.1    Dinarello, C.A.2
  • 29
    • 0001572284 scopus 로고
    • Nutrition needs of mammalian cells in tissue culture
    • Eagle H. Nutrition needs of mammalian cells in tissue culture. Science 1955; 122:501-14.
    • (1955) Science , vol.122 , pp. 501-514
    • Eagle, H.1
  • 30
    • 75149148563 scopus 로고    scopus 로고
    • Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
    • DeBerardinis RJ, Cheng T. Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 2010; 29:313-24.
    • (2010) Oncogene , vol.29 , pp. 313-324
    • DeBerardinis, R.J.1    Cheng, T.2
  • 31
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen HN. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 1990; 70:43-77.
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 32
    • 84900440370 scopus 로고    scopus 로고
    • Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation
    • Elsevier Inc
    • Nakaya M, Xiao Y, Zhou X, Chang J-H, Chang M, Cheng X et al. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity Elsevier Inc; 2014; 40:692-705.
    • (2014) Immunity , vol.40 , pp. 692-705
    • Nakaya, M.1    Xiao, Y.2    Zhou, X.3    Chang, J.-H.4    Chang, M.5    Cheng, X.6
  • 33
    • 0142213223 scopus 로고    scopus 로고
    • Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes
    • Nandakumar KS, Svensson L, Holmdahl R. Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. Am J Pathol 2003; 163:1827-37.
    • (2003) Am J Pathol , vol.163 , pp. 1827-1837
    • Nandakumar, K.S.1    Svensson, L.2    Holmdahl, R.3
  • 34
    • 0035423403 scopus 로고    scopus 로고
    • Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
    • Wipke BT, Allen PM. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 2001; 167:1601-8.
    • (2001) J Immunol , vol.167 , pp. 1601-1608
    • Wipke, B.T.1    Allen, P.M.2
  • 35
    • 77950364465 scopus 로고    scopus 로고
    • Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function-associated antigen 1
    • Monach PA, Nigrovic PA, Chen M, Hock H, Lee DM, Benoist C et al. Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis Rheum 2010; 62:753-64.
    • (2010) Arthritis Rheum , vol.62 , pp. 753-764
    • Monach, P.A.1    Nigrovic, P.A.2    Chen, M.3    Hock, H.4    Lee, D.M.5    Benoist, C.6
  • 36
    • 33748751857 scopus 로고    scopus 로고
    • Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis
    • Tanaka D, Kagari T, Doi H, Shimozato T. Essential role of neutrophils in anti-type II collagen antibody and lipopolysaccharide-induced arthritis. Immunology 2006; 119:195-202.
    • (2006) Immunology , vol.119 , pp. 195-202
    • Tanaka, D.1    Kagari, T.2    Doi, H.3    Shimozato, T.4
  • 37
    • 84877089880 scopus 로고    scopus 로고
    • Neutrophils are essential as a source of IL-17 in the effector phase of arthritis
    • Katayama M, Ohmura K, Yukawa N, Terao C, Hashimoto M, Yoshifuji H et al. Neutrophils are essential as a source of IL-17 in the effector phase of arthritis. PLoS One 2013; 8:e62231.
    • (2013) PLoS One , vol.8 , pp. e62231
    • Katayama, M.1    Ohmura, K.2    Yukawa, N.3    Terao, C.4    Hashimoto, M.5    Yoshifuji, H.6
  • 38
    • 84355162334 scopus 로고    scopus 로고
    • Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo
    • Elsevier Inc
    • Biburger M, Aschermann S, Schwab I, Lux A, Albert H, Danzer H et al. Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo. Immunity Elsevier Inc; 2011; 35:932-44.
    • (2011) Immunity , vol.35 , pp. 932-944
    • Biburger, M.1    Aschermann, S.2    Schwab, I.3    Lux, A.4    Albert, H.5    Danzer, H.6
  • 40
    • 34547199003 scopus 로고    scopus 로고
    • T cells are involved in the development of arthritis induced by anti-type II collagen antibody
    • Mitamura M, Nakano N, Yonekawa T, Shan L, Kaise T, Kobayashi T et al. T cells are involved in the development of arthritis induced by anti-type II collagen antibody. Int Immunopharmacol 2007; 7:1360-8.
    • (2007) Int Immunopharmacol , vol.7 , pp. 1360-1368
    • Mitamura, M.1    Nakano, N.2    Yonekawa, T.3    Shan, L.4    Kaise, T.5    Kobayashi, T.6
  • 41
    • 84855275402 scopus 로고    scopus 로고
    • Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis
    • Chiba A, Tajima R, Tomi C, Miyazaki Y, Yamamura T, Miyake S. Mucosal-associated invariant T cells promote inflammation and exacerbate disease in murine models of arthritis. Arthritis Rheum 2012; 64:153-61.
    • (2012) Arthritis Rheum , vol.64 , pp. 153-161
    • Chiba, A.1    Tajima, R.2    Tomi, C.3    Miyazaki, Y.4    Yamamura, T.5    Miyake, S.6
  • 42
    • 0036299010 scopus 로고    scopus 로고
    • Selective up-regulation of system a transporter mRNA in diabetic liver
    • Varoqui H, Erickson JD. Selective up-regulation of system a transporter mRNA in diabetic liver. Biochem Biophys Res Commun 2002; 290:903-8.
    • (2002) Biochem Biophys Res Commun , vol.290 , pp. 903-908
    • Varoqui, H.1    Erickson, J.D.2
  • 43
    • 34248584526 scopus 로고    scopus 로고
    • Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus
    • Toukap AN, Galant C, Theate I, Maudoux AL, Lories RJU, Houssiau FA et al. Identification of distinct gene expression profiles in the synovium of patients with systemic lupus erythematosus. Arthritis Rheum 2007; 56:1579-88.
    • (2007) Arthritis Rheum , vol.56 , pp. 1579-1588
    • Toukap, A.N.1    Galant, C.2    Theate, I.3    Maudoux, A.L.4    Lories, R.J.U.5    Houssiau, F.A.6
  • 44
    • 34548571952 scopus 로고    scopus 로고
    • Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic liver tissues
    • Kondoh N, Imazeki N, Arai M, Hada A, Hatsuse K, Matsuo H et al. Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic liver tissues. Int J Oncol 2007; 31:81-7.
    • (2007) Int J Oncol , vol.31 , pp. 81-87
    • Kondoh, N.1    Imazeki, N.2    Arai, M.3    Hada, A.4    Hatsuse, K.5    Matsuo, H.6
  • 46
    • 84885448500 scopus 로고    scopus 로고
    • Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development
    • Wang Q, Tiffen J, Bailey CG, Lehman ML, Ritchie W, Fazli L et al. Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development. J Natl Cancer Inst 2013; 105:1463-73.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1463-1473
    • Wang, Q.1    Tiffen, J.2    Bailey, C.G.3    Lehman, M.L.4    Ritchie, W.5    Fazli, L.6
  • 47
    • 84880017125 scopus 로고    scopus 로고
    • Activation of SNAT1/SLC38A1 in human breast cancer: correlation with p-Akt overexpression
    • Wang K, Cao F, Fang W, Hu Y, Chen Y, Ding H et al. Activation of SNAT1/SLC38A1 in human breast cancer: correlation with p-Akt overexpression. BMC Cancer 2013; 13:343.
    • (2013) BMC Cancer , vol.13 , pp. 343
    • Wang, K.1    Cao, F.2    Fang, W.3    Hu, Y.4    Chen, Y.5    Ding, H.6
  • 48
    • 84901603736 scopus 로고    scopus 로고
    • shRNA-mediated Slc38a1 silencing inhibits migration, but not invasiveness of human pancreatic cancer cells
    • Xie J, Chen Z, Liu L, Li P, Zhu X, Gao H et al. shRNA-mediated Slc38a1 silencing inhibits migration, but not invasiveness of human pancreatic cancer cells. Chin J Cancer Res 2013; 25:514-9.
    • (2013) Chin J Cancer Res , vol.25 , pp. 514-519
    • Xie, J.1    Chen, Z.2    Liu, L.3    Li, P.4    Zhu, X.5    Gao, H.6
  • 49
    • 84873363313 scopus 로고    scopus 로고
    • SLC1A5 mediates glutamine transport required for lung cancer cell growth and survival
    • Hassanein M, Hoeksema MD, Shiota M, Qian J, Harris BK, Chen H et al. SLC1A5 mediates glutamine transport required for lung cancer cell growth and survival. Clin Cancer Res 2013; 19:560-70.
    • (2013) Clin Cancer Res , vol.19 , pp. 560-570
    • Hassanein, M.1    Hoeksema, M.D.2    Shiota, M.3    Qian, J.4    Harris, B.K.5    Chen, H.6
  • 50
    • 84901823650 scopus 로고    scopus 로고
    • ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer
    • Shimizu K, Kaira K, Tomizawa Y, Sunaga N, Kawashima O, Oriuchi N et al. ASC amino-acid transporter 2 (ASCT2) as a novel prognostic marker in non-small cell lung cancer. Br J Cancer 2014; 110:2030-9.
    • (2014) Br J Cancer , vol.110 , pp. 2030-2039
    • Shimizu, K.1    Kaira, K.2    Tomizawa, Y.3    Sunaga, N.4    Kawashima, O.5    Oriuchi, N.6
  • 51
    • 84898882636 scopus 로고    scopus 로고
    • Overexpression of SLC38A1 is associated with poorer prognosis in Chinese patients with gastric cancer
    • Xie J, Li P, Gao H-F, Qian J-X, Yuan L-Y, Wang J-J. Overexpression of SLC38A1 is associated with poorer prognosis in Chinese patients with gastric cancer. BMC Gastroenterol 2014; 14:70.
    • (2014) BMC Gastroenterol , vol.14 , pp. 70
    • Xie, J.1    Li, P.2    Gao, H.-F.3    Qian, J.-X.4    Yuan, L.-Y.5    Wang, J.-J.6
  • 53
  • 56
    • 0019969734 scopus 로고
    • Distribution of some non-physiological amino acids (AIB, DAB, MeAIB) in mice
    • Appelgren LE, Lindqvist I, Nilsson O, Ronquist G. Distribution of some non-physiological amino acids (AIB, DAB, MeAIB) in mice. Acta Physiol Scand 1982; 115:261-8.
    • (1982) Acta Physiol Scand , vol.115 , pp. 261-268
    • Appelgren, L.E.1    Lindqvist, I.2    Nilsson, O.3    Ronquist, G.4
  • 60
    • 84869227264 scopus 로고    scopus 로고
    • Treatment strategies in early rheumatoid arthritis and prevention of rheumatoid arthritis
    • Demoruelle MK, Deane KD. Treatment strategies in early rheumatoid arthritis and prevention of rheumatoid arthritis. Curr Rheumatol Rep 2012; 14:472-80.
    • (2012) Curr Rheumatol Rep , vol.14 , pp. 472-480
    • Demoruelle, M.K.1    Deane, K.D.2
  • 61
    • 84887970040 scopus 로고    scopus 로고
    • Water-soluble undenatured type II collagen ameliorates collagen-induced arthritis in mice
    • Yoshinari O, Shiojima Y, Moriyama H, Shinozaki J, Nakane T, Masuda K et al. Water-soluble undenatured type II collagen ameliorates collagen-induced arthritis in mice. J Med Food 2013; 16:1039-45.
    • (2013) J Med Food , vol.16 , pp. 1039-1045
    • Yoshinari, O.1    Shiojima, Y.2    Moriyama, H.3    Shinozaki, J.4    Nakane, T.5    Masuda, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.