The genotypic and phenotypic stability of plasmodium falciparum field isolates in continuous in vitro culture

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Yeda, Redemptah ^a   Ingasia, Luicer A ^a   Cheruiyot, Agnes C ^a   Okudo, Charles ^a   Chebon, Lorna J ^a,b   Cheruiyot, Jelagat ^a   Akala, Hoseah M ^a   Kamau, Edwin ^a  

^a U S ARMY   (United States)

^b JOMO KENYATTA UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER; BENFLUMETOL; CHLOROQUINE; DIHYDROARTEMISININ; ANTIMALARIAL AGENT; MICROSATELLITE DNA; PROTOZOAL DNA;

ALLELE; ANTIMALARIAL DRUG RESISTANCE; ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CONTINUOUS CULTURE; CONTROLLED STUDY; CORRELATIONAL STUDY; DNA STRUCTURE; GENE LOCUS; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC STABILITY; GENETIC VARIABILITY; GENOTYPIC STABILITY; HAPLOTYPE; HETEROZYGOSITY; IC50; IN VITRO STUDY; MICROSATELLITE; MOLECULAR DYNAMICS; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PHENOTYPIC STABILITY; PLASMODIUM FALCIPARUM; SINGLE NUCLEOTIDE POLYMORPHISM; CLASSIFICATION; DRUG EFFECTS; DRUG RESISTANCE; ERYTHROCYTE; GENE FREQUENCY; GENETICS; GENOME; GENOMIC INSTABILITY; GENOTYPE; HUMAN; KENYA; PARASITOLOGY; PHENOTYPE; PHYLOGENY; PRIMARY CELL CULTURE;

ALLELES; ANTIMALARIALS; DNA, PROTOZOAN; DRUG RESISTANCE; ERYTHROCYTES; GENE FREQUENCY; GENOME, PROTOZOAN; GENOMIC INSTABILITY; GENOTYPE; HUMANS; INHIBITORY CONCENTRATION 50; KENYA; MICROSATELLITE REPEATS; MULTILOCUS SEQUENCE TYPING; PHENOTYPE; PHYLOGENY; PLASMODIUM FALCIPARUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PRIMARY CELL CULTURE;

EID: 84954421981     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0143565     Document Type: Article

References (30)

1. Trager W, Jensen JB. Continuous culture of Plasmodium falciparum: its impact on malaria research. Int J Parasitol. 1997; 27(9):989-1006. Epub 1997/11/18. doi:S0020751997000805 [pii]. PMID: 9363481.
2. Fidock DA, Nomura T, Talley AK, Cooper RA, Dzekunov SM, Ferdig MT, et al. Mutations in the P. falciparum digestive vacuole transmembrane protein PFCRT and evidence for their role in chloroquine resistance. Mol Cell. 2000; 6(4):861-71. Epub 2000/11/25. doi: S1097-2765(05)00077-8 [pii]. PMID: 11090624.
3. Foote SJ, Kyle DE, Martin RK, Oduola AM, Forsyth K, Kemp DJ, et al. Several alleles of the multidrugresistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature. 1990; 345(6272):255-8. Epub 1990/05/17. doi:10.1038/345255a0 PMID: 2185424.
4. Gaur D, Storry JR, Reid ME, Barnwell JW, Miller LH. Plasmodium falciparum is able to invade erythrocytes through a trypsin-resistant pathway independent of glycophorin B. Infect Immun. 2003; 71(12): 6742-6. Epub 2003/11/26. PMID: 14638759.
5. Manske M, Miotto O, Campino S, Auburn S, Almagro-Garcia J, Maslen G, et al. Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature. 2012; 485(7407):375-9. doi:10.1038/nature11174.
6. Bacon DJ, Jambou R, Fandeur T, Le Bras J, Wongsrichanalai C, Fukuda MM, et al. World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility. Malar J. 2007; 6:120. Epub 2007/09/08. doi: 1475-2875-6-120 [pii] doi:10.1186/1475-2875-6-120 PMID: 17822533.
7. van Schalkwyk DA, Burrow R, Henriques G, Gadalla NB, Beshir KB, Hasford C, et al. Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers. Malar J. 2013; 12:320. Epub 2013/09/14. doi: 1475-2875-12-320 [pii] doi:10.1186/1475-2875-12-320 PMID: 24028570.
8. Anderson TJ, Haubold B, Williams JT, Estrada-Franco JG, Richardson L, Mollinedo R, et al. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Molecular Biology Evolution. 2000; 17(10):1467-82. PMID: 11018154.
9. Babiker HA, Lines J, Hill WG, Walliker D. Population structure of Plasmodium falciparum in villages with different malaria endemicity in east Africa. Am J Trop Med Hyg. 1997; 56(2):141-7. Epub 1997/02/01. PMID: 9080871.
10. Paul RE, Packer MJ, Walmsley M, Lagog M, Ranford-Cartwright LC, Paru R, et al. Mating patterns in malaria parasite populations of Papua New Guinea. Science. 1995; 269(5231):1709-11. Epub 1995/09/22. PMID: 7569897.
11. Farnert A, Lebbad M, Faraja L, Rooth I. Extensive dynamics of Plasmodium falciparum densities, stages and genotyping profiles. Malar J. 2008; 7:241. Epub 2008/11/26. doi: 1475-2875-7-241 [pii] doi:10.1186/1475-2875-7-241PMID: 19025582.
12. Anderson TJ, Su XZ, Bockarie M, Lagog M, Day KP. Twelve microsatellite markers for characterization of Plasmodium falciparum from finger-prick blood samples. Parasitology. 1999; 119(Pt2):113-25. PMID: 10466118.
13. Co EM, Dennull RA, Reinbold DD, Waters NC, Johnson JD. Assessment of malaria in vitro drug combination screening and mixed-strain infections using the malaria Sybr green I-based fluorescence assay. Antimicrob Agents Chemother. 2009; 53:2557-63. doi:10.1128/AAC.01370-08 PMID: 19349518.
14. Eyase FL, Akala HM, Ingasia L, Cheruiyot A, Omondi A, Okudo C, et al. The role of Pfmdr1 and Pfcrt in changing chloroquine, amodiaquine, mefloquine and lumefantrine susceptibility in western-Kenya P. falciparum samples during 2008-2011. Plos One. 2013; 8(5):e64299. doi:10.1371/journal.pone.0064299 PMID: 23675533.
15. Akala HM, Eyase FL, Cheruiyot AC, Omondi AA, Ogutu BR, Waters NC, et al. Antimalarial drug sensitivity profile of western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay and molecular analysis. Am J Trop Med Hyg. 2011; 85(1):34-41. PMID: 21734121.
16. Trager W, Jensen JB. Human malaria parasites in continuous culture. Science. 1976; 193(4254): 673-5. Epub 1976/08/20. PMID: 781840.
17. Johnson DS, Mortazavi A, Myers RM, Wold B. Genome-wide mapping of in vivo protein-DNA interactions. Science. 2007; 316(5830):1497-502. PMID: 17540862.
18. Smilkstein M, Sriwilaijaroen N, Kelly JX, Wilairat P, Riscoe M. Simple and inexpensive fluorescencebased technique for high-throughput antimalarial drug screening. Antimicrob Agents Chemother 2004; 48:1803-6. PMID: 15105138.
19. Akala HM, Achieng AO, Eyase FL, Juma DW, Ingasia L, Cheruiyot AC, et al. Five-year tracking of Plasmodium falciparum allele frequencies in a holoendemic area with indistinct seasonal transitions. J Multidiscip Health. 2014; 7:515-23. doi:10.2147/JMDH.S67252.
20. Gabriel S, Ziaugra L, Tabbaa D. SNP genotyping using the Sequenom MassARRAY iPLEX platform. Curr Protoc Hum Genet 2009; Chapter 2(Unit 2 12.).
21. Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, et al. A molecular marker of artemisinin- resistant Plasmodium falciparum malaria. Nature. 2014; 505(7481):50-5. doi:10.1038/nature12876 PMID: 24352242.
22. Babiker HA, Abdel-Muhsin AM, Ranford-Cartwright LC, Satti G, Walliker D. Characteristics of Plasmodium falciparum parasites that survive the lengthy dry season in eastern Sudan where malaria transmission is markedly seasonal. Am J Trop Med Hyg. 1998; 59(4):582-90. Epub 1998/10/28. PMID: 9790434.
23. Felger I, Maire M, Bretscher MT, Falk N, Tiaden A, Sama W, et al. The dynamics of natural Plasmodium falciparum infections. PLoS One. 1998; 7(9):e45542. Epub 2012/10/03. doi:10.1371/journal.pone. 0045542 PONE-D-12-14929 [pii]. PMID: 23029082.
24. Witkowski B, Amaratunga C, Khim N, Sreng S, Chim P, Kim S, et al. Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies. Lancet Infect Dis. 2013; 13(12):1043-9. doi:10.1016/S1473-3099(13)70252-4 PMID: 24035558.
25. Basco LK. Field application of in vitro assays for the sensitivity of human malaria parasites to antimalarial drugs. Geneva, World Health Organization. 2007.
26. Ofosu-Okyere A, Mackinnon MJ, Sowa MP, Koram KA, Nkrumah F, Osei YD, et al. Novel Plasmodium falciparum clones and rising clone multiplicities are associated with the increase inmalariamorbidity in Ghanaian children during the transition into the high transmission season. Parasitology. 2001; 123(Pt2): 113-23. Epub 2001/08/21. PMID: 11510676.
27. Smith T, Felger I, Kitua A, Tanner M, Beck HP. Dynamics of multiple Plasmodium falciparum infections in infants in a highly endemic area of Tanzania. Trans R Soc Trop Med Hyg. 1999; 93 Suppl1:35-9. Epub 1999/08/18. PMID: 10450424.
28. Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, et al. Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002; 419(6906):498-511. Epub 2002/10/09. doi:10.1038/nature01097nature01097 [pii]. PMID: 12368864.
29. WHO. Global report on antimalarial drug efficacy and drug resistance; Geneva. 2010.
30. Tyner S, Lon C, Se Y, Bethell D, Socheat D, Noedl H, et al. Ex vivo drug sensitivity profiles of Plasmodium falciparum field isolates from Cambodia and Thailand, 2005 to 2010, determined by a histidinerich protein-2 assay. Malaria Journal. 2012; 11(1):198. doi:10.1186/1475-2875-11-198.