Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9

ACS Synthetic Biology

Volumn 5, Issue 1, 2016, Pages 81-88

  Didovyk, Andriy ^a,b   Borek, Bartłomiej ^a,b   Hasty, Jeff ^a,b,c,d   Tsimring, Lev ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b University of California San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CRISPR Cas9; orthogonal repressors; synthetic gene circuit engineering

Indexed keywords

CRISPR ASSOCIATED PROTEIN; CRISPR CAS9 PROTEIN; GUIDE RNA; UNCLASSIFIED DRUG; REPRESSOR PROTEIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA REPLICATION ORIGIN; DNA SEQUENCE; ENTEROBACTERIA PHAGE LAMBDA; ESCHERICHIA COLI; GENE REPRESSION; GENE TARGETING; GENETIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SYNTHETIC BIOLOGY; CRISPR CAS SYSTEM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROCEDURES; REPRODUCIBILITY; TRANSCRIPTION INITIATION SITE;

BINDING SITES; CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC ENGINEERING; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; REPRODUCIBILITY OF RESULTS; TRANSCRIPTION INITIATION SITE;

EID: 84954421331     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00147     Document Type: Article

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