Degradation of the Intermediate Filament Family by Gigaxonin

Methods in Enzymology

Volumn 569, Issue , 2016, Pages 215-231

  Bomont, Pascale ^a,b  

^a Atip Avenir Team   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

BTB Kelch protein; E3 ligase; Giant axonal neuropathy; Gigaxonin; Intermediate filament degradation; Neurodegeneration; Neurofilament; Vimentin

Indexed keywords

ADAPTOR PROTEIN; GIGAXONIN; PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; GAN PROTEIN, MOUSE;

GENETIC TRANSFECTION; HUMAN; INTERMEDIATE FILAMENT; METHODOLOGY; NEUROFILAMENT; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SKIN FIBROBLAST; TURNOVER TIME; UPREGULATION; ANIMAL; METABOLISM; PHYSIOLOGY;

ANIMALS; CYTOSKELETAL PROTEINS; HUMANS; INTERMEDIATE FILAMENTS; PROTEOLYSIS;

EID: 84954368286     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/bs.mie.2015.07.009     Document Type: Chapter

References (30)

1. E. Allen, J. Ding, W. Wang, S. Pramanik, J. Chou, V. Yau, and et al. Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival Nature 438 7065 2005 224 228
2. A.K. Asbury, M.K. Gale, S.C. Cox, J.R. Baringer, and B.O. Berg Giant axonal neuropathy - A unique case with segmental neurofilamentous masses Acta Neuropathologica 20 3 1972 237 247
3. M. Balastik, F. Ferraguti, A. Pires-da Silva, T.H. Lee, G. Alvarez-Bolado, K.P. Lu, and et al. Deficiency in ubiquitin ligase TRIM2 causes accumulation of neurofilament light chain and neurodegeneration Proceedings of the National Academy of Sciences of the United States of America 105 33 2008 12016 12021
4. A. Bocquet, R. Berges, R. Frank, P. Robert, A.C. Peterson, and J. Eyer Neurofilaments bind tubulin and modulate its polymerization The Journal of Neuroscience 29 35 2009 11043 11054
5. P. Bomont, L. Cavalier, F. Blondeau, C. Ben Hamida, S. Belal, M. Tazir, and et al. The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy Nature Genetics 26 3 2000 370 374
6. P. Bomont, and M. Koenig Intermediate filament aggregation in fibroblasts of giant axonal neuropathy patients is aggravated in non dividing cells and by microtubule destabilization Human Molecular Genetics 12 8 2003 813 822
7. J. Cassereau, G. Nicolas, P. Lonchampt, M. Pinier, A. Barthelaix, J. Eyer, and et al. Axonal regeneration is compromised in NFH-LacZ transgenic mice but not in NFH-GFP mice Neuroscience 228 2013 101 108
8. D.W. Cleveland, K. Yamanaka, and P. Bomont Gigaxonin controls vimentin organization through a tubulin chaperone-independent pathway Human Molecular Genetics 18 8 2009 1384 1394
9. V.C. Cullen, J. Brownlees, S. Banner, B.H. Anderton, P.N. Leigh, C.E. Shaw, and et al. Gigaxonin is associated with the Golgi and dimerises via its BTB domain Neuroreport 15 5 2004 873 876
10. F. Dequen, P. Bomont, G. Gowing, D.W. Cleveland, and J.P. Julien Modest loss of peripheral axons, muscle atrophy and formation of brain inclusions in mice with targeted deletion of gigaxonin exon 1 Journal of Neurochemistry 107 1 2008 253 264
11. J. Ding, E. Allen, W. Wang, A. Valle, C. Wu, T. Nardine, and et al. Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport Human Molecular Genetics 15 9 2006 1451 1463
12. J. Ding, J.J. Liu, A.S. Kowal, T. Nardine, P. Bhattacharya, A. Lee, and et al. Microtubule-associated protein 1B: A neuronal binding partner for gigaxonin The Journal of Cell Biology 158 3 2002 427 433
13. M. Donaghy, R.H. King, P.K. Thomas, and J.M. Workman Abnormalities of the axonal cytoskeleton in giant axonal neuropathy Journal of Neurocytology 17 2 1988 197 208
14. M. Furukawa, Y.J. He, C. Borchers, and Y. Xiong Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases Nature Cell Biology 5 11 2003 1001 1007
15. T. Ganay, A. Boizot, R. Burrer, J.P. Chauvin, and P. Bomont Sensory-motor deficits and neurofilament disorganization in gigaxonin-null mice Molecular Neurodegeneration 12 6 2011 25
16. J.P. Gou, and J.F. Leterrier Possible involvement of ubiquitination in neurofilament degradation Biochemical and Biophysical Research Communications 217 2 1995 529 538
17. V. Ionasescu, C. Searby, P. Rubenstein, A. Sandra, P. Cancilla, and J. Robillard Giant axonal neuropathy: Normal protein composition of neurofilaments Journal of Neurology, Neurosurgery and Psychiatry 46 6 1983 551 554
18. C.J. Klein, Y. Wu, P. Vogel, H.H. Goebel, C. Bonnemann, K. Zukosky, and et al. Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons Neurology 82 2014 873 878
19. D. Kortazar, M.L. Fanarraga, G. Carranza, J. Bellido, J.C. Villegas, J. Avila, and et al. Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation Experimental Cell Research 313 2007 425 436
20. G. Kuhlenbaumer, V. Timmerman, and P. Bomont Giant axonal neuropathy R.A. Pagon, M.P. Adam, H.H. Ardinger, S.E. Wallace, A. Amemiya, L.J.H. Bean, T.D. Bird, C.R. Dolan, C.T. Fong, R.J.H. Smith, K. Stephens, GeneReviews® [Internet] 1993 University of Washington, Seattle Seattle (WA) 1993-2015
21. S. Mahammad, S.N. Murthy, A. Didonna, B. Grin, E. Israeli, R. Perrot, and et al. Giant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation The Journal of Clinical Investigation 123 5 2013 1964 1975
22. S. Millecamps, G. Gowing, O. Corti, J. Mallet, and J.P. Julien Conditional NF-L transgene expression in mice for in vivo analysis of turnover and transport rate of neurofilaments The Journal of Neuroscience 27 18 2007 4947 4956
23. R.A. Nixon, and K.B. Logvinenko Multiple fates of newly synthesized neurofilament proteins: Evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons The Journal of Cell Biology 102 2 1986 647 659
24. S.D. Pena Giant axonal neuropathy: Intermediate filament aggregates in cultured skin fibroblasts Neurology 31 11 1981 1470 1473
25. R. Perrot, R. Berges, A. Bocquet, and J. Eyer Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration Molecular Neurobiology 38 1 2008 27 65
26. J.W. Prineas, R.A. Ouvrier, R.G. Wright, J.C. Walsh, and J.G. McLeod Gian axonal neuropathy - A generalized disorder of cytoplasmic microfilament formation Journal of Neuropathology and Experimental Neurology 35 4 1976 458 470
27. M.V. Rao, A. Yuan, J. Campbell, A. Kumar, and R.A. Nixon The C-terminal domains of NF-H and NF-M subunits maintain axonal neurofilament content by blocking turnover of the stationary neurofilament network PLoS One 7 9 2012 e44320
28. W. Wang, J. Ding, E. Allen, P. Zhu, L. Zhang, H. Vogel, and et al. Gigaxonin interacts with tubulin folding cofactor B and controls its degradation through the ubiquitin-proteasome pathway Current Biology 15 22 2005 2050 2055
29. J.T. Wang, Z.A. Medress, and B.A. Barres Axon degeneration: Molecular mechanisms of a self-destruction pathway The Journal of Cell Biology 196 1 2012 7 18
30. E. Ylikallio, R. Poyhonen, M. Zimon, E. De Vriendt, T. Hilander, A. Paetau, and et al. Deficiency of the E3 ubiquitin ligase TRIM2 in early-onset axonal neuropathy Human Molecular Genetics 22 15 2013 2975 2983