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Volumn 37, Issue 1, 2016, Pages 72-80

Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA6 INTEGRIN; CD34 ANTIGEN; CELL NUCLEUS ANTIGEN; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRILYSIN; ORNITHINE DECARBOXYLASE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA; PROTEIN KINASE C MU; PROTEIN KINASE C ZETA; STAT3 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; 7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; PHORBOL 13 ACETATE 12 MYRISTATE;

EID: 84954350238     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv162     Document Type: Article
Times cited : (10)

References (57)
  • 1
    • 4243795083 scopus 로고    scopus 로고
    • Anonymous, American Cancer Society, Cancer facts and figures 2014. Atlanta: American Cancer Society
    • Anonymous (2014) Skin cancer. American Cancer Society, Cancer facts and figures 2014. Atlanta: American Cancer Society.
    • (2014) Skin cancer
  • 2
    • 0034025493 scopus 로고    scopus 로고
    • Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters
    • Kazanietz, M.G. (2000) Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters. Mol. Carcinog., 28, 5-11.
    • (2000) Mol. Carcinog , vol.28 , pp. 5-11
    • Kazanietz, M.G.1
  • 3
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor, H. et al. (1998) The extended protein kinase C superfamily. Biochem. J., 332 (Pt 2), 281-292.
    • (1998) Biochem. J , vol.332 , pp. 281-292
    • Mellor, H.1
  • 4
    • 27644504484 scopus 로고    scopus 로고
    • Modulating protein kinase C signal transduction
    • Mochly-Rosen, D. et al. (1998) Modulating protein kinase C signal transduction. Adv. Pharmacol., 44, 91-145.
    • (1998) Adv. Pharmacol , vol.44 , pp. 91-145
    • Mochly-Rosen, D.1
  • 5
    • 77349122303 scopus 로고    scopus 로고
    • Protein kinase C: poised to signal
    • Newton, A.C. (2010) Protein kinase C: poised to signal. Am. J. Physiol. Endocrinol. Metab., 298, E395-E402.
    • (2010) Am. J. Physiol. Endocrinol. Metab , vol.298 , pp. E395-E402
    • Newton, A.C.1
  • 6
    • 0035413601 scopus 로고    scopus 로고
    • Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
    • Newton, A.C. (2001) Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions. Chem. Rev., 101, 2353-2364.
    • (2001) Chem. Rev , vol.101 , pp. 2353-2364
    • Newton, A.C.1
  • 7
    • 1542547319 scopus 로고    scopus 로고
    • The ins and outs of protein kinase C
    • Newton, A.C. (2003) The ins and outs of protein kinase C. Methods Mol. Biol., 233, 3-7.
    • (2003) Methods Mol. Biol , vol.233 , pp. 3-7
    • Newton, A.C.1
  • 8
    • 0032491318 scopus 로고    scopus 로고
    • Protein kinase Cdelta is activated by caspasedependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes
    • Denning, M.F. et al. (1998) Protein kinase Cdelta is activated by caspasedependent proteolysis during ultraviolet radiation-induced apoptosis of human keratinocytes. J. Biol. Chem., 273, 29995-30002.
    • (1998) J. Biol. Chem , vol.273 , pp. 29995-30002
    • Denning, M.F.1
  • 9
    • 0033951214 scopus 로고    scopus 로고
    • Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion
    • Reddig, P.J. et al. (2000) Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion. Cancer Res., 60, 595-602.
    • (2000) Cancer Res , vol.60 , pp. 595-602
    • Reddig, P.J.1
  • 10
    • 0035452342 scopus 로고    scopus 로고
    • Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and-epsilon transgenic mice
    • Jansen, A.P. et al. (2001) Relation of the induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, -delta and-epsilon transgenic mice. Int. J. Cancer, 93, 635-643.
    • (2001) Int. J. Cancer , vol.93 , pp. 635-643
    • Jansen, A.P.1
  • 11
    • 0035110896 scopus 로고    scopus 로고
    • Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma
    • Jansen, A.P. et al. (2001) Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma. Cancer Res., 61, 808-812.
    • (2001) Cancer Res , vol.61 , pp. 808-812
    • Jansen, A.P.1
  • 12
    • 7444232271 scopus 로고    scopus 로고
    • Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas
    • Wheeler, D.L. et al. (2004) Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas. Cancer Res., 64, 7756-7765.
    • (2004) Cancer Res , vol.64 , pp. 7756-7765
    • Wheeler, D.L.1
  • 13
    • 0141918880 scopus 로고    scopus 로고
    • Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice
    • Wheeler, D.L. et al. (2003) Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice. Cancer Res., 63, 6547-6555.
    • (2003) Cancer Res , vol.63 , pp. 6547-6555
    • Wheeler, D.L.1
  • 14
    • 31544472620 scopus 로고    scopus 로고
    • Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice
    • Li, Y. et al. (2005) Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice. Toxicol. Pathol., 33, 684-694.
    • (2005) Toxicol. Pathol , vol.33 , pp. 684-694
    • Li, Y.1
  • 15
    • 33744978353 scopus 로고    scopus 로고
    • Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer
    • Verma, A.K. et al. (2006) Protein kinase Cepsilon and development of squamous cell carcinoma, the nonmelanoma human skin cancer. Mol. Carcinog., 45, 381-388.
    • (2006) Mol. Carcinog , vol.45 , pp. 381-388
    • Verma, A.K.1
  • 16
    • 14744270572 scopus 로고    scopus 로고
    • Protein kinase C epsilon signals ultraviolet light-induced cutaneous damage and development of squamous cell carcinoma possibly through Induction of specific cytokines in a paracrine mechanism
    • Wheeler, D.L. et al. (2005) Protein kinase C epsilon signals ultraviolet light-induced cutaneous damage and development of squamous cell carcinoma possibly through Induction of specific cytokines in a paracrine mechanism. Photochem. Photobiol., 81, 9-18.
    • (2005) Photochem. Photobiol , vol.81 , pp. 9-18
    • Wheeler, D.L.1
  • 17
    • 0032983865 scopus 로고    scopus 로고
    • Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis
    • Moore, R.J. et al. (1999) Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis. Nat. Med., 5, 828-831.
    • (1999) Nat. Med , vol.5 , pp. 828-831
    • Moore, R.J.1
  • 18
    • 0027251830 scopus 로고
    • Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation
    • Komori, A. et al. (1993) Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation. Cancer Res., 53, 1982-1985.
    • (1993) Cancer Res , vol.53 , pp. 1982-1985
    • Komori, A.1
  • 19
    • 0034125358 scopus 로고    scopus 로고
    • Role for tumour necrosis factor-alpha receptors in ultraviolet-induced skin tumours
    • Starcher, B. (2000) Role for tumour necrosis factor-alpha receptors in ultraviolet-induced skin tumours. Br. J. Dermatol., 142, 1140-1147.
    • (2000) Br. J. Dermatol , vol.142 , pp. 1140-1147
    • Starcher, B.1
  • 20
    • 84925367433 scopus 로고    scopus 로고
    • Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas
    • Singh, A. et al. (2015) Topically applied Hsp90 inhibitor 17AAG inhibits UVR-induced cutaneous squamous cell carcinomas. J. Invest. Dermatol., 135, 1098-1107.
    • (2015) J. Invest. Dermatol , vol.135 , pp. 1098-1107
    • Singh, A.1
  • 21
    • 31544446018 scopus 로고    scopus 로고
    • Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2
    • Aziz, M.H. et al. (2006) Protein kinase C delta overexpressing transgenic mice are resistant to chemically but not to UV radiation-induced development of squamous cell carcinomas: a possible link to specific cytokines and cyclooxygenase-2. Cancer Res., 66, 713-722.
    • (2006) Cancer Res , vol.66 , pp. 713-722
    • Aziz, M.H.1
  • 22
    • 84898914212 scopus 로고    scopus 로고
    • Protein kinase C, which is linked to ultraviolet radiation-induced development of squamous cell carcinomas, stimulates rapid turnover of adult hair follicle stem cells
    • Singh, A. et al. (2013) Protein kinase C, which is linked to ultraviolet radiation-induced development of squamous cell carcinomas, stimulates rapid turnover of adult hair follicle stem cells. J. Skin Cancer, 2013, 452425.
    • (2013) J. Skin Cancer , vol.2013
    • Singh, A.1
  • 24
    • 22544473782 scopus 로고    scopus 로고
    • Cary, NC: SAS Institute
    • Institute, S. Inc. (2005) SAS OnlineDoc 9.1.3. Cary, NC: SAS Institute.
    • (2005) SAS OnlineDoc 9.1.3
  • 25
    • 72049119612 scopus 로고    scopus 로고
    • PKCepsilon overexpression, irrespective of genetic background, sensitizes skin to UVR-induced development of squamous-cell carcinomas
    • Sand, J.M. et al. (2010) PKCepsilon overexpression, irrespective of genetic background, sensitizes skin to UVR-induced development of squamous-cell carcinomas. J. Invest. Dermatol., 130, 270-277.
    • (2010) J. Invest. Dermatol , vol.130 , pp. 270-277
    • Sand, J.M.1
  • 26
    • 0026514526 scopus 로고
    • Two TNF receptors
    • Tartaglia, L.A. et al. (1992) Two TNF receptors. Immunol. Today, 13, 151-153.
    • (1992) Immunol. Today , vol.13 , pp. 151-153
    • Tartaglia, L.A.1
  • 27
    • 0029114596 scopus 로고
    • Two tumour necrosis factor receptors: structure and function
    • Vandenabeele, P. et al. (1995) Two tumour necrosis factor receptors: structure and function. Trends Cell Biol., 5, 392-399.
    • (1995) Trends Cell Biol , vol.5 , pp. 392-399
    • Vandenabeele, P.1
  • 28
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: integrating mammalian biology
    • Locksley, R.M. et al. (2001) The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell, 104, 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1
  • 29
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: a beautiful pathway
    • Chen, G. et al. (2002) TNF-R1 signaling: a beautiful pathway. Science, 296, 1634-1635.
    • (2002) Science , vol.296 , pp. 1634-1635
    • Chen, G.1
  • 30
    • 0036184885 scopus 로고    scopus 로고
    • TNF ligands and receptors-a matter of life and death
    • MacEwan, D.J. (2002) TNF ligands and receptors-a matter of life and death. Br. J. Pharmacol., 135, 855-875.
    • (2002) Br. J. Pharmacol , vol.135 , pp. 855-875
    • MacEwan, D.J.1
  • 31
    • 58149158032 scopus 로고    scopus 로고
    • TNF-alpha production in the skin
    • Bashir, M.M. et al. (2009) TNF-alpha production in the skin. Arch. Dermatol. Res., 301, 87-91.
    • (2009) Arch. Dermatol. Res , vol.301 , pp. 87-91
    • Bashir, M.M.1
  • 32
    • 0026566646 scopus 로고
    • Mechanisms of tumor necrosis factor action
    • Schutze, S. et al. (1992) Mechanisms of tumor necrosis factor action. Semin. Oncol., 19, 16-24.
    • (1992) Semin. Oncol , vol.19 , pp. 16-24
    • Schutze, S.1
  • 33
    • 0031816326 scopus 로고    scopus 로고
    • Squamous cell cancer: a practical approach
    • Goldman, G.D. (1998) Squamous cell cancer: a practical approach. Semin. Cutan. Med. Surg., 17, 80-95.
    • (1998) Semin. Cutan. Med. Surg , vol.17 , pp. 80-95
    • Goldman, G.D.1
  • 35
    • 0038393124 scopus 로고    scopus 로고
    • The death effector domain protein family: regulators of cellular homeostasis
    • Tibbetts, M.D. et al. (2003) The death effector domain protein family: regulators of cellular homeostasis. Nat. Immunol., 4, 404-409.
    • (2003) Nat. Immunol , vol.4 , pp. 404-409
    • Tibbetts, M.D.1
  • 36
    • 0642283970 scopus 로고    scopus 로고
    • Regulation of proliferation, survival and apoptosis by members of the TNF superfamily
    • Gaur, U. et al. (2003) Regulation of proliferation, survival and apoptosis by members of the TNF superfamily. Biochem. Pharmacol., 66, 1403-1408.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 1403-1408
    • Gaur, U.1
  • 37
    • 3042819700 scopus 로고    scopus 로고
    • Death receptor activation complexes: it takes two to activate TNF receptor 1
    • Sheikh, M.S. et al. (2003) Death receptor activation complexes: it takes two to activate TNF receptor 1. Cell Cycle, 2, 550-552.
    • (2003) Cell Cycle , vol.2 , pp. 550-552
    • Sheikh, M.S.1
  • 38
    • 0242656497 scopus 로고    scopus 로고
    • Death receptor-induced cell killing
    • Thorburn, A. (2004) Death receptor-induced cell killing. Cell. Signal., 16, 139-144.
    • (2004) Cell. Signal , vol.16 , pp. 139-144
    • Thorburn, A.1
  • 39
    • 67651102487 scopus 로고    scopus 로고
    • Protein kinase Cepsilon inhibits UVR-induced expression of FADD, an adaptor protein, linked to both Fas-and TNFR1-mediated apoptosis
    • Aziz, M.H. et al. (2009) Protein kinase Cepsilon inhibits UVR-induced expression of FADD, an adaptor protein, linked to both Fas-and TNFR1-mediated apoptosis. J. Invest. Dermatol., 129, 2011-2021.
    • (2009) J. Invest. Dermatol , vol.129 , pp. 2011-2021
    • Aziz, M.H.1
  • 40
    • 0347634454 scopus 로고    scopus 로고
    • Defining the epithelial stem cell niche in skin
    • Tumbar, T. et al. (2004) Defining the epithelial stem cell niche in skin. Science, 303, 359-363.
    • (2004) Science , vol.303 , pp. 359-363
    • Tumbar, T.1
  • 41
    • 34547889548 scopus 로고    scopus 로고
    • A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer
    • Kangsamaksin, T. et al. (2007) A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer. Mol. Carcinog., 46, 579-584.
    • (2007) Mol. Carcinog , vol.46 , pp. 579-584
    • Kangsamaksin, T.1
  • 42
    • 0344177195 scopus 로고    scopus 로고
    • Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34
    • Trempus, C.S. et al. (2003) Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J. Invest. Dermatol., 120, 501-511.
    • (2003) J. Invest. Dermatol , vol.120 , pp. 501-511
    • Trempus, C.S.1
  • 43
    • 34249789291 scopus 로고    scopus 로고
    • Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice
    • Faurschou, A. et al. (2007) Squamous cell carcinoma induced by ultraviolet radiation originates from cells of the hair follicle in mice. Exp. Dermatol., 16, 485-489.
    • (2007) Exp. Dermatol , vol.16 , pp. 485-489
    • Faurschou, A.1
  • 44
    • 0034650889 scopus 로고    scopus 로고
    • Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles
    • Morris, R.J. et al. (2000) Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles. Cancer Res., 60, 226-229.
    • (2000) Cancer Res , vol.60 , pp. 226-229
    • Morris, R.J.1
  • 45
    • 34249275713 scopus 로고    scopus 로고
    • CD34 expression by hair follicle stem cells is required for skin tumor development in mice
    • Trempus, C.S. et al. (2007) CD34 expression by hair follicle stem cells is required for skin tumor development in mice. Cancer Res., 67, 4173-4181.
    • (2007) Cancer Res , vol.67 , pp. 4173-4181
    • Trempus, C.S.1
  • 46
    • 84864348419 scopus 로고    scopus 로고
    • Brief report: requirement of TACE/ADAM17 for hair follicle bulge niche establishment
    • Nagao, K. et al. (2012) Brief report: requirement of TACE/ADAM17 for hair follicle bulge niche establishment. Stem Cells, 30, 1781-1785.
    • (2012) Stem Cells , vol.30 , pp. 1781-1785
    • Nagao, K.1
  • 47
    • 77952958193 scopus 로고    scopus 로고
    • Protein kinase Cvarepsilon mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression, and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2, and ERK1/2)
    • Aziz, M.H. et al. (2010) Protein kinase Cvarepsilon mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression, and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2, and ERK1/2). Oncogene, 29, 3100-3109.
    • (2010) Oncogene , vol.29 , pp. 3100-3109
    • Aziz, M.H.1
  • 48
    • 34548787911 scopus 로고    scopus 로고
    • Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer
    • Aziz, M.H. et al. (2007) Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer. Cancer Res., 67, 8828-8838.
    • (2007) Cancer Res , vol.67 , pp. 8828-8838
    • Aziz, M.H.1
  • 49
    • 1842586795 scopus 로고    scopus 로고
    • Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development
    • Arnott, C.H. et al. (2004) Expression of both TNF-alpha receptor subtypes is essential for optimal skin tumour development. Oncogene, 23, 1902-1910.
    • (2004) Oncogene , vol.23 , pp. 1902-1910
    • Arnott, C.H.1
  • 50
    • 0043175218 scopus 로고    scopus 로고
    • Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer
    • Kerkelä, E. et al. (2003) Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer. Exp. Dermatol., 12, 109-125.
    • (2003) Exp. Dermatol , vol.12 , pp. 109-125
    • Kerkelä, E.1
  • 51
    • 4644262855 scopus 로고    scopus 로고
    • TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration?
    • Scott, K.A. et al. (2004) TNF-alpha regulates epithelial expression of MMP-9 and integrin alphavbeta6 during tumour promotion. A role for TNF-alpha in keratinocyte migration? Oncogene, 23, 6954-6966.
    • (2004) Oncogene , vol.23 , pp. 6954-6966
    • Scott, K.A.1
  • 52
    • 0024362088 scopus 로고
    • AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells
    • Bernstein, L.R. et al. (1989) AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science, 244, 566-569.
    • (1989) Science , vol.244 , pp. 566-569
    • Bernstein, L.R.1
  • 53
    • 84903712349 scopus 로고    scopus 로고
    • Epidermal p65/NF-kappaB signalling is essential for skin carcinogenesis
    • Kim, C. et al. (2014) Epidermal p65/NF-kappaB signalling is essential for skin carcinogenesis. EMBO Mol. Med., 6, 970-983.
    • (2014) EMBO Mol. Med , vol.6 , pp. 970-983
    • Kim, C.1
  • 54
    • 7444269111 scopus 로고    scopus 로고
    • Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocytemacrophage colony-stimulating factor in the progression of skin carcinoma cells
    • Obermueller, E. et al. (2004) Cooperative autocrine and paracrine functions of granulocyte colony-stimulating factor and granulocytemacrophage colony-stimulating factor in the progression of skin carcinoma cells. Cancer Res., 64, 7801-7812.
    • (2004) Cancer Res , vol.64 , pp. 7801-7812
    • Obermueller, E.1
  • 55
    • 0034790570 scopus 로고    scopus 로고
    • Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor
    • Mueller, M.M. et al. (2001) Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. Am. J. Pathol., 159, 1567-1579.
    • (2001) Am. J. Pathol , vol.159 , pp. 1567-1579
    • Mueller, M.M.1
  • 56
    • 35348854953 scopus 로고    scopus 로고
    • Interleukin-12 and photocarcinogenesis
    • Katiyar, S.K. (2007) Interleukin-12 and photocarcinogenesis. Toxicol. Appl. Pharmacol., 224, 220-227.
    • (2007) Toxicol. Appl. Pharmacol , vol.224 , pp. 220-227
    • Katiyar, S.K.1
  • 57
    • 0032437087 scopus 로고    scopus 로고
    • Cytokines and irritant contact dermatitis
    • Corsini, E. et al. (1998) Cytokines and irritant contact dermatitis. Toxicol. Lett., 102-103, 277-282.
    • (1998) Toxicol. Lett , vol.102-103 , pp. 277-282
    • Corsini, E.1


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