Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCε overexpressing transgenic mice

Toxicologic Pathology

Volumn 33, Issue 6, 2005, Pages 684-694

  Li, Yafan ^a   Wheeler, Deric L ^b   Alters, Wade ^c   Chaiswing, Luksana ^c   Verma, Ajit K ^a,c,d   Oberley, Terry D ^a,c,e  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d Medical School   (United States)

^e WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

Author keywords

Cell death; Hyperplasia; Polymorphonuclear neutrophils; Protein kinase C epsilon; Skin; Transgenic mice

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C EPSILON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL INFILTRATION; CELL REGENERATION; CONTROLLED STUDY; EPIDERMIS; EPIDERMIS CELL; EPIDERMIS HYPERPLASIA; FEMALE; HAIR FOLLICLE; HISTOLOGY; MOUSE; NEUTROPHIL; NONHUMAN; OVARY FOLLICLE CELL; PAPILLOMA; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN ABRASION; SKIN NECROSIS; SQUAMOUS CELL CARCINOMA; TRANSGENIC MOUSE; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMOTAXIS, LEUKOCYTE; COCARCINOGENESIS; DISEASE MODELS, ANIMAL; EPIDERMIS; FEMALE; HAIR FOLLICLE; HYPERPLASIA; KERATIN-10; KERATINOCYTES; KERATINS; MICE; MICE, TRANSGENIC; NEUTROPHILS; PHENOTYPE; PRECANCEROUS CONDITIONS; PROTEIN KINASE C-EPSILON; SKIN; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS;

ANIMALIA; MUS MUSCULUS;

EID: 31544472620     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1080/01926230500323441     Document Type: Article

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