PKCε overexpression, irrespective of genetic background, sensitizes skin to uvr-induced development of squamous-cell carcinomas

Journal of Investigative Dermatology

Volumn 130, Issue 1, 2010, Pages 270-277

  Sand, Jordan M ^a   Aziz, Moammir H ^a   Dreckschmidt, Nancy E ^a   Havighurst, Thomas C ^b   Kim, Kyungmann ^b   Oberley, Terry D ^a   Verma, Ajit K ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b University of Wisconsin Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLINE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C EPSILON; STAT3 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CANCER INCIDENCE; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; CROSS BREEDING; FEMALE; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HAIRLESS MOUSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; RADIATION EXPOSURE; SKIN CARCINOMA; SKIN SENSITIZATION; SQUAMOUS CELL CARCINOMA; TRANSGENIC MOUSE; ULTRAVIOLET RADIATION; WILD TYPE; ANIMAL; CELL NUCLEUS; ENZYMOLOGY; EPIDERMIS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RADIATION RESPONSE; SKIN TUMOR; SPECIES DIFFERENCE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL NUCLEUS; DOSE-RESPONSE RELATIONSHIP, RADIATION; EPIDERMIS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; MALE; MICE; MICE, HAIRLESS; MICE, TRANSGENIC; PHOSPHORYLATION; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN KINASE C-EPSILON; SKIN NEOPLASMS; SPECIES SPECIFICITY; STAT3 TRANSCRIPTION FACTOR; ULTRAVIOLET RAYS;

EID: 72049119612     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2009.212     Document Type: Article

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