PLGA-curcumin attenuates opioid-induced hyperalgesia and inhibits spinal CaMKIIα

PLoS ONE

Volumn 11, Issue 1, 2016, Pages

  Hu, Xiaoyu ^a   Huang, Fang ^a   Szymusiak, Magdalena ^b   Tian, Xuebi ^a,c   Liu, Ying ^a,b   Wang, Zaijie Jim ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b 1120 Science and Engineering Offices   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IIALPHA; CURCUMIN; MORPHINE SULFATE; POLYGLACTIN; UNCLASSIFIED DRUG; LACTIC ACID; MORPHINE; NANOMATERIAL; NARCOTIC ANALGESIC AGENT; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG MEGADOSE; DRUG SOLUBILITY; ENZYME ACTIVATION; ENZYME INHIBITION; EVENING DOSAGE; HEAT SENSITIVITY; HYPERALGESIA; IMMUNOBLOTTING; MALE; MECHANICAL STIMULATION; MORNING DOSAGE; MOUSE; NANOENCAPSULATION; NONHUMAN; OPIOID INDUCED HYPERALGESIA; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; CHEMISTRY; CHRONIC PAIN; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG TOLERANCE; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PAIN MEASUREMENT; PATHOPHYSIOLOGY; PROCEDURES;

ANALGESICS, OPIOID; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CHRONIC PAIN; CURCUMIN; DRUG DELIVERY SYSTEMS; DRUG TOLERANCE; HYPERALGESIA; LACTIC ACID; MALE; MICE; MICE, INBRED ICR; MORPHINE; NANOSTRUCTURES; PAIN MEASUREMENT; POLYGLYCOLIC ACID; SPINAL CORD DORSAL HORN;

EID: 84954350138     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0146393     Document Type: Article

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