Curcumin attenuates opioid tolerance and dependence by inhibiting Ca2+/calmodulin-dependent protein kinase II α activity

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 3, 2015, Pages 420-428

  Hu, Xiaoyu ^a   Huang, Fang ^a   Szymusiak, Magdalena ^b   Liu, Ying ^a,b   Wang, Zaijie Jim ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b University of Illinois at Chicago   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II ALPHA; CURCUMIN; MORPHINE; NANOPARTICLE; POLYGLACTIN; UNCLASSIFIED DRUG; ENZYME INHIBITOR; LACTIC ACID; NARCOTIC ANALGESIC AGENT; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG FORMULATION; DRUG MECHANISM; DRUG SOLUBILITY; DRUG TOLERANCE; ENZYME ACTIVATION; ENZYME INHIBITION; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; LOCOMOTION; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OPIATE ADDICTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PHYSIOLOGY;

ANALGESICS, OPIOID; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; ENZYME ACTIVATION; ENZYME INHIBITORS; LACTIC ACID; MALE; MICE; MICE, INBRED ICR; NANOPARTICLES; POLYGLYCOLIC ACID;

EID: 84921526409     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.219303     Document Type: Article

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