Complement Factor B production in renal tubular cells and its role in sodium transporter expression during polymicrobial sepsis

Critical Care Medicine

Volumn 44, Issue 5, 2016, Pages e289-e299

  Li, Dan ^a,b   Zou, Lin ^a   Feng, Yan ^a   Xu, Ganqiong ^a   Gong, Yu ^a   Zhao, Gaofeng ^a   Ouyang, Wen ^b   Thurman, Joshua M ^c   Chao, Wei ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

acute kidney injury; complement factor B; sepsis; Toll like receptors; tubular cells

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; CPG OLIGODEOXYNUCLEOTIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN P50; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; 3-(4-METHYLPHENYLSULFONYL)-2-PROPENENITRILE; EPITHELIAL SODIUM CHANNEL; NITRILE; POTASSIUM CHANNEL; SULFONE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CELL CULTURE; CELL STIMULATION; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY TUBULE CELL; KIDNEY TUBULE EPITHELIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; SHAM PROCEDURE; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE; ACTIVE TRANSPORT; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; DISEASE MODEL; GENETICS; KIDNEY; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; COMPLEMENT FACTOR B; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EPITHELIAL SODIUM CHANNELS; FEMALE; GENE EXPRESSION; HUMANS; KIDNEY; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; NITRILES; POTASSIUM CHANNELS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEPSIS; SIGNAL TRANSDUCTION; SULFONES; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 84954348364     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001566     Document Type: Article

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