-
1
-
-
84897531613
-
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
-
Sun C, Wang L, Huang S, Heynen GJ, Prahallad A, Robert C et al. Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma. Nature 2014; 508: 118-122.
-
(2014)
Nature
, vol.508
, pp. 118-122
-
-
Sun, C.1
Wang, L.2
Huang, S.3
Heynen, G.J.4
Prahallad, A.5
Robert, C.6
-
2
-
-
78650309875
-
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
-
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA et al. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature 2010; 468: 968-972.
-
(2010)
Nature
, vol.468
, pp. 968-972
-
-
Johannessen, C.M.1
Boehm, J.S.2
Kim, S.Y.3
Thomas, S.R.4
Wardwell, L.5
Johnson, L.A.6
-
3
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian R, Shi H, Wang Q, Kong X, Koya RC, Lee H et al. Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 2010; 468: 973-977.
-
(2010)
Nature
, vol.468
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
Kong, X.4
Koya, R.C.5
Lee, H.6
-
4
-
-
84891894051
-
The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma
-
Van Allen EM, Wagle N, Sucker A, Treacy DJ, Johannessen CM, Goetz EM et al. The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma. Cancer Discov 2014; 4: 94-109.
-
(2014)
Cancer Discov
, vol.4
, pp. 94-109
-
-
Van Allen, E.M.1
Wagle, N.2
Sucker, A.3
Treacy, D.J.4
Johannessen, C.M.5
Goetz, E.M.6
-
5
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB et al. Improved survival with ipilimumab in patients with metastatic melanoma. NEnglJ Med 2010; 363: 711-723.
-
(2010)
NEnglJ Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
-
6
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364: 2517-2526.
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
-
7
-
-
84898973055
-
Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab
-
Topalian SL, Sznol M, McDermott DF, Kluger HM, Carvajal RD, Sharfman WH et al. Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab. J Clin Oncol 2014; 32: 1020-1030.
-
(2014)
J Clin Oncol
, vol.32
, pp. 1020-1030
-
-
Topalian, S.L.1
Sznol, M.2
McDermott, D.F.3
Kluger, H.M.4
Carvajal, R.D.5
Sharfman, W.H.6
-
8
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
-
Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013; 369: 134-144.
-
(2013)
N Engl J Med
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.J.5
Kefford, R.6
-
9
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012; 366: 2443-2454.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
10
-
-
36849061558
-
Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: A meta-analysis of 18 trials involving 2,621 patients
-
Ives NJ, Stowe RL, Lorigan P, Wheatley K. Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: a meta-analysis of 18 trials involving 2,621 patients. J Clin Oncol 2007; 25: 5426-5434.
-
(2007)
J Clin Oncol
, vol.25
, pp. 5426-5434
-
-
Ives, N.J.1
Stowe, R.L.2
Lorigan, P.3
Wheatley, K.4
-
11
-
-
79952613370
-
Systematic review of medical treatment in melanoma: Current status and future prospects
-
Garbe C, Eigentler TK, Keilholz U, Hauschild A, Kirkwood JM. Systematic review of medical treatment in melanoma: current status and future prospects. Oncologist 2011; 16: 5-24.
-
(2011)
Oncologist
, vol.16
, pp. 5-24
-
-
Garbe, C.1
Eigentler, T.K.2
Keilholz, U.3
Hauschild, A.4
Kirkwood, J.M.5
-
12
-
-
84882267015
-
Management of primary cutaneous and metastatic melanoma
-
Rubin KM. Management of primary cutaneous and metastatic melanoma. Semin Oncol Nurs 2013; 29: 195-205.
-
(2013)
Semin Oncol Nurs
, vol.29
, pp. 195-205
-
-
Rubin, K.M.1
-
13
-
-
5444220651
-
Adjuvant interferon therapy for melanoma: High-dose, low-dose, no dose, which dose?
-
Schuchter LM. Adjuvant interferon therapy for melanoma: high-dose, low-dose, no dose, which dose? J Clin Oncol 2004; 22: 7-10.
-
(2004)
J Clin Oncol
, vol.22
, pp. 7-10
-
-
Schuchter, L.M.1
-
14
-
-
84863012289
-
PKCepsilon promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria
-
Lau E, Kluger H, Varsano T, Lee K, Scheffler I, Rimm DL et al. PKCepsilon promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria. Cell 2012; 148: 543-555.
-
(2012)
Cell
, vol.148
, pp. 543-555
-
-
Lau, E.1
Kluger, H.2
Varsano, T.3
Lee, K.4
Scheffler, I.5
Rimm, D.L.6
-
15
-
-
84921985051
-
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
-
Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld T, Kang TW et al. In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer. Nat Med 2014; 20: 1138-1146.
-
(2014)
Nat Med
, vol.20
, pp. 1138-1146
-
-
Rudalska, R.1
Dauch, D.2
Longerich, T.3
McJunkin, K.4
Wuestefeld, T.5
Kang, T.W.6
-
16
-
-
1642447684
-
Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity
-
Bhoumik A, Jones N, Ronai Z. Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity. Proc Natl Acad Sci USA 2004; 101: 4222-4227.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 4222-4227
-
-
Bhoumik, A.1
Jones, N.2
Ronai, Z.3
-
17
-
-
84878041279
-
Inhibition of melanoma growth by small molecules that promote the mitochondrial localization of ATF2
-
Varsano T, Lau E, Feng Y, Garrido M, Milan L, Heynen-Genel S et al. Inhibition of melanoma growth by small molecules that promote the mitochondrial localization of ATF2. Clin Cancer Res 2013; 19: 2710-2722.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2710-2722
-
-
Varsano, T.1
Lau, E.2
Feng, Y.3
Garrido, M.4
Milan, L.5
Heynen-Genel, S.6
-
18
-
-
0037226818
-
DNA replication-dependent nuclear dynamics of the Mre11 complex
-
Mirzoeva OK, Petrini JH. DNA replication-dependent nuclear dynamics of the Mre11 complex. Mol Cancer Res 2003; 1: 207-218.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 207-218
-
-
Mirzoeva, O.K.1
Petrini, J.H.2
-
19
-
-
84878556423
-
Vemurafenib induces senescence features in melanoma cells
-
Haferkamp S, Borst A, Adam C, Becker TM, Motschenbacher S, Windhovel S et al. Vemurafenib induces senescence features in melanoma cells. J Invest Dermatol 2013; 133: 1601-1609.
-
(2013)
J Invest Dermatol
, vol.133
, pp. 1601-1609
-
-
Haferkamp, S.1
Borst, A.2
Adam, C.3
Becker, T.M.4
Motschenbacher, S.5
Windhovel, S.6
-
20
-
-
84896877541
-
Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation
-
Pencheva N, Buss CG, Posada J, Merghoub T, Tavazoie SF. Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation. Cell 2014; 156: 986-1001.
-
(2014)
Cell
, vol.156
, pp. 986-1001
-
-
Pencheva, N.1
Buss, C.G.2
Posada, J.3
Merghoub, T.4
Tavazoie, S.F.5
-
21
-
-
32944480188
-
Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: Outcome prediction in a multicenter trial
-
Koyanagi K, O'Day SJ, Gonzalez R, Lewis K, Robinson WA, Amatruda TT et al. Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: outcome prediction in a multicenter trial. J Clin Oncol 2005; 23: 8057-8064.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8057-8064
-
-
Koyanagi, K.1
O'Day, S.J.2
Gonzalez, R.3
Lewis, K.4
Robinson, W.A.5
Amatruda, T.T.6
-
22
-
-
77950968549
-
Serial monitoring of circulating tumor cells predicts outcome of induction biochemotherapy plus maintenance biotherapy for metastatic melanoma
-
Koyanagi K, O'Day SJ, Boasberg P, Atkins MB, Wang HJ, Gonzalez R et al. Serial monitoring of circulating tumor cells predicts outcome of induction biochemotherapy plus maintenance biotherapy for metastatic melanoma. Clin Cancer Res 2010; 16: 2402-2408.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2402-2408
-
-
Koyanagi, K.1
O'Day, S.J.2
Boasberg, P.3
Atkins, M.B.4
Wang, H.J.5
Gonzalez, R.6
-
23
-
-
84865793305
-
Innate immune sensing of cancer: Clues from an identified role for type I IFNs
-
Gajewski TF, Fuertes MB, Woo SR. Innate immune sensing of cancer: clues from an identified role for type I IFNs. Cancer Immunol Immunother 2012; 61: 1343-1347.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1343-1347
-
-
Gajewski, T.F.1
Fuertes, M.B.2
Woo, S.R.3
-
24
-
-
0035930550
-
Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages
-
Jacobs AT, Ignarro LJ. Lipopolysaccharide-induced expression of interferon-beta mediates the timing of inducible nitric-oxide synthase induction in RAW 264.7 macrophages. J Biol Chem 2001; 276: 47950-47957.
-
(2001)
J Biol Chem
, vol.276
, pp. 47950-47957
-
-
Jacobs, A.T.1
Ignarro, L.J.2
-
25
-
-
0036230176
-
Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways
-
Malmgaard L, Salazar-Mather TP, Lewis CA, Biron CA. Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways. J Virol 2002; 76: 4520-4525.
-
(2002)
J Virol
, vol.76
, pp. 4520-4525
-
-
Malmgaard, L.1
Salazar-Mather, T.P.2
Lewis, C.A.3
Biron, C.A.4
-
26
-
-
77956410302
-
NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication
-
Wang J, Basagoudanavar SH, Wang X, Hopewell E, Albrecht R, Garcia-Sastre A et al. NF-kappa B RelA subunit is crucial for early IFN-beta expression and resistance to RNA virus replication. J Immunol 2010; 185: 1720-1729.
-
(2010)
J Immunol
, vol.185
, pp. 1720-1729
-
-
Wang, J.1
Basagoudanavar, S.H.2
Wang, X.3
Hopewell, E.4
Albrecht, R.5
Garcia-Sastre, A.6
-
27
-
-
0033989205
-
Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma
-
Middleton MR, Grob JJ, Aaronson N, Fierlbeck G, Tilgen W, Seiter S et al. Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma. J Clin Oncol 2000; 18: 158-166.
-
(2000)
J Clin Oncol
, vol.18
, pp. 158-166
-
-
Middleton, M.R.1
Grob, J.J.2
Aaronson, N.3
Fierlbeck, G.4
Tilgen, W.5
Seiter, S.6
-
28
-
-
30744461590
-
Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma
-
Rao RD, Holtan SG, Ingle JN, Croghan GA, Kottschade LA, Creagan ET et al. Combination of paclitaxel and carboplatin as second-line therapy for patients with metastatic melanoma. Cancer 2006; 106: 375-382.
-
(2006)
Cancer
, vol.106
, pp. 375-382
-
-
Rao, R.D.1
Holtan, S.G.2
Ingle, J.N.3
Croghan, G.A.4
Kottschade, L.A.5
Creagan, E.T.6
-
29
-
-
70349575099
-
Surgery and radiotherapy in the treatment of cutaneous melanoma
-
Testori A, Rutkowski P, Marsden J, Bastholt L, Chiarion-Sileni V, Hauschild A et al. Surgery and radiotherapy in the treatment of cutaneous melanoma. Ann Oncol 2009; 20: vi22-vi29.
-
(2009)
Ann Oncol
, vol.20
, pp. vi22-vi29
-
-
Testori, A.1
Rutkowski, P.2
Marsden, J.3
Bastholt, L.4
Chiarion-Sileni, V.5
Hauschild, A.6
-
30
-
-
19444363740
-
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response
-
Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z. ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell 2005; 18: 577-587.
-
(2005)
Mol Cell
, vol.18
, pp. 577-587
-
-
Bhoumik, A.1
Takahashi, S.2
Breitweiser, W.3
Shiloh, Y.4
Jones, N.5
Ronai, Z.6
-
31
-
-
84906080024
-
Analysis of the expression of interleukins, interferon beta, and nuclear factor-kappa B in prostate cancer and their relationship with biochemical recurrence
-
Eiro N, Bermudez-Fernandez S, Fernandez-Garcia B, Atienza S, Beridze N, Escaf S et al. Analysis of the expression of interleukins, interferon beta, and nuclear factor-kappa B in prostate cancer and their relationship with biochemical recurrence. J Immunother 2014; 37: 366-373.
-
(2014)
J Immunother
, vol.37
, pp. 366-373
-
-
Eiro, N.1
Bermudez-Fernandez, S.2
Fernandez-Garcia, B.3
Atienza, S.4
Beridze, N.5
Escaf, S.6
-
32
-
-
84905109684
-
An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival
-
Snijders AM, Langley S, Mao JH, Bhatnagar S, Bjornstad KA, Rosen CJ et al. An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival. Oncotarget 2014; 5: 4011-4025.
-
(2014)
Oncotarget
, vol.5
, pp. 4011-4025
-
-
Snijders, A.M.1
Langley, S.2
Mao, J.H.3
Bhatnagar, S.4
Bjornstad, K.A.5
Rosen, C.J.6
-
33
-
-
84906059145
-
Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-beta and suppress the growth of MCF-7 human breast cancer cells
-
Ryu H, Oh JE, Rhee KJ, Baik SK, Kim J, Kang SJ et al. Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-beta and suppress the growth of MCF-7 human breast cancer cells. Cancer Lett 2014; 352: 220-227.
-
(2014)
Cancer Lett
, vol.352
, pp. 220-227
-
-
Ryu, H.1
Oh, J.E.2
Rhee, K.J.3
Baik, S.K.4
Kim, J.5
Kang, S.J.6
-
34
-
-
84906569017
-
Interferon-alpha acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line
-
Maeda S, Wada H, Naito Y, Nagano H, Simmons S, Kagawa Y et al. Interferon-alpha acts on the S/G2/M phases to induce apoptosis in the G1 phase of an IFNAR2-expressing hepatocellular carcinoma cell line. J Biol Chem 2014; 289: 23786-23795.
-
(2014)
J Biol Chem
, vol.289
, pp. 23786-23795
-
-
Maeda, S.1
Wada, H.2
Naito, Y.3
Nagano, H.4
Simmons, S.5
Kagawa, Y.6
-
35
-
-
84925283155
-
Host STAT2/type I interferon axis controls tumor growth
-
Yue C, Xu J, Tan Estioko MD, Kotredes KP, Lopez-Otalora Y, Hilliard BA et al. Host STAT2/type I interferon axis controls tumor growth. Int J Cancer 2014; 136: 117-126.
-
(2014)
Int J Cancer
, vol.136
, pp. 117-126
-
-
Yue, C.1
Xu, J.2
Tan Estioko, M.D.3
Kotredes, K.P.4
Lopez-Otalora, Y.5
Hilliard, B.A.6
|