Discovery of serum metabolites for diagnosis of progression of mild cognitive impairment to Alzheimer's disease using an optimized metabolomics method

RSC Advances

Volumn 6, Issue 5, 2016, Pages 3586-3591

  Liang, Qun ^a   Liu, Han ^b   Zhang, Tianyu ^a   Jiang, Yan ^a   Xing, Haitao ^a   Zhang, Ai Hua ^a  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BODY FLUIDS; DIAGNOSIS; METABOLISM; METABOLITES; NEURODEGENERATIVE DISEASES;

7-KETOCHOLESTEROL; ALZHEIMER'S DISEASE; DIAGNOSIS TOOLS; MILD COGNITIVE IMPAIRMENTS; MILD COGNITIVE IMPAIRMENTS (MCI); POTENTIAL VALUES; PREDICTIVE MODELING; SERUM SAMPLES;

PRINCIPAL COMPONENT ANALYSIS;

EID: 84954306838     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c5ra19349d     Document Type: Article

References (22)

1. A. Aguzzi Neurodegeneration: Alzheimer's disease under strain Nature 2014 512 7512 32 34
2. L. H. Tsai R. Madabhushi Alzheimer's disease: a protective factor for the ageing brain Nature 2014 507 7493 439 440
3. J. M. Nussbaum S. Schilling H. Cynis A. Silva E. Swanson T. Wangsanut K. Tayler B. Wiltgen A. Hatami R. Rönicke K. Reymann B. Hutter-Paier A. Alexandru W. Jagla S. Graubner C. G. Glabe H. U. Demuth G. S. Bloom Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β Nature 2012 485 7400 651 655
4. J. C. Chen M. J. Alvarez F. Talos H. Dhruv G. E. Rieckhof A. Iyer K. L. Diefes K. Aldape M. Berens M. M. Shen A. Califano Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks Cell 2014 159 2 402 414
5. S. Salloway R. Sperling H. R. Brashear Phase 3 trials of solanezumab and bapineuzumab for Alzheimer's disease N. Engl. J. Med. 2014 370 15 1460
6. Q. Liang H. Liu T. Zhang et al., Metabolomics-based screening of salivary biomarkers for early diagnosis of Alzheimer's disease RSC Adv. 2015 5 116 96074 96079
7. T. Takayama T. Mochizuki K. Todoroki J. Z. Min H. Mizuno K. Inoue H. Akatsu I. Noge T. Toyo'oka A novel approach for LC-MS/MS-based chiral metabolomics fingerprinting and chiral metabolomics extraction using a pair of enantiomers of chiral derivatization reagents Anal. Chim. Acta 2015 898 73 84
8. V. M. Barnes A. D. Kennedy F. Panagakos W. Devizio H. M. Trivedi T. Jönsson L. Guo S. Cervi F. A. Scannapieco Global metabolomic analysis of human serum and plasma from healthy and diabetic subjects, with and without periodontal disease PLoS One 2014 9 8 e105181
9. J. Zheng R. A. Dixon L. Li Development of isotope labeling LC-MS for human serum metabolomics and application to profiling metabolome changes associated with mild cognitive impairment Anal. Chem. 2012 84 24 10802 10811
10. Q. Liang C. Wang B. Li et al., Metabolomics of alcoholic liver disease: a clinical discovery study RSC Adv. 2015 5 98 80381 80387
11. A. Zhang H. Sun X. Wang Serum metabolomics opens door to biomarker discovery, disease diagnosis, and treatment Appl. Biochem. Biotechnol. 2012 168 6 1718 1727
12. A. R. Pfenning E. Hara O. Whitney M. V. Rivas R. Wang P. L. Roulhac J. T. Howard M. Wirthlin P. V. Lovell G. Ganapathy J. Mouncastle M. A. Moseley J. W. Thompson E. J. Soderblom A. Iriki M. Kato M. T. Gilbert G. Zhang T. Bakken A. Bongaarts A. Bernard E. Lein C. V. Mello A. J. Hartemink E. D. Jarvis Convergent transcriptional specializations in the brains of humans and song-learning birds Science 2014 346 6215 1256846
13. K. L. Poulson-Ellestad C. M. Jones J. Roy M. R. Viant F. M. Fernández J. Kubanek B. L. Nunn Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton Proc. Natl. Acad. Sci. U. S. A. 2014 111 24 9009 9014
14. G. Kageyama J. Saegusa Y. Irino S. Tanaka K. Tsuda S. Takahashi S. Sendo A. Morinobu Metabolomics analysis of serum from patients with primary Sjögren's syndrome Clin. Exp. Immunol. 2015 5 124
15. A. H. Zhang H. Sun Y. Han G. L. Yan Y. Yuan G. C. Song X. X. Yuan N. Xie X. J. Wang Ultraperformance liquid chromatography-mass spectrometry based comprehensive metabolomics combined with pattern recognition and network analysis methods for characterization of metabolites and metabolic pathways from biological data sets Anal. Chem. 2013 85 15 7606 7612
16. Q. Liang H. Liu T. Zhang Y. Jiang H. Xing A. H. Zhang Potential urine biomarkers from a high throughput metabolomics study of severe sepsis in a large Asian cohort RSC Adv. 2015 5 124 102204 102209
17. G. E. Smith R. C. Petersen J. E. Parisi R. J. Ivnik E. Kokmen E. G. Tangalos et al., Definition, course, and outcome of mild cognitive impairment Aging Neuropsychol. Cognit. 1996 3 141 147
18. L. Berg Clinical Dementia Rating (CDR) Psychopharmacol. Bull. 1988 24 637 639
19. S. J. Bruce I. Tavazzi V. Parisod S. Rezzi S. Kochhar P. A. Guy Investigation of human blood plasma sample preparation for performing metabolomics using ultrahigh performance liquid chromatography/mass spectrometry Anal. Chem. 2009 81 9 3285 3296
20. R. González-Domínguez T. García-Barrera J. L. Gómez-Ariza Using direct infusion mass spectrometry for serum metabolomics in Alzheimer's disease Anal. Bioanal. Chem. 2014 406 28 7137 7148
21. G. Wang Y. Zhou F. J. Huang H. D. Tang X. H. Xu J. J. Liu Y. Wang Y. L. Deng R. J. Ren W. Xu J. F. Ma Y. N. Zhang A. H. Zhao S. D. Chen W. Jia Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment J. Proteome Res. 2014 13 5 2649 2658
22. R. González-Domínguez A. García T. García-Barrera C. Barbas J. L. Gómez-Ariza Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry Electrophoresis 2014 35 23 3321 3330