Metabolomics-based screening of salivary biomarkers for early diagnosis of Alzheimer's disease

RSC Advances

Volumn 5, Issue 116, 2015, Pages 96074-96079

  Liang, Qun ^a   Liu, Han ^b   Zhang, Tianyu ^a   Jiang, Yan ^a   Xing, Haitao ^a   Zhang, Ai Hua ^a  

^a HEILONGJIANG UNIVERSITY OF CHINESE MEDICINE   (China)

^b SIMON FRASER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOMARKERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; MULTIVARIANT ANALYSIS; NEURODEGENERATIVE DISEASES; PRINCIPAL COMPONENT ANALYSIS;

ALZHEIMER'S DISEASE; ATTRACTIVE STRATEGIES; CLINICAL SETTINGS; METABOLIC CHANGES; MULTIVARIATE STATISTICAL METHOD; PREDICTIVE MODELING; SALIVARY BIOMARKERS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

DIAGNOSIS;

EID: 84946944959     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c5ra19094k     Document Type: Article

References (29)

1. A. Aguzzi Neurodegeneration: Alzheimer's disease under strain Nature 2014 512 32 34
2. L. H. Tsai R. Madabhushi Alzheimer's disease: A protective factor for the ageing brain Nature 2014 507 439 440
3. J. M. Nussbaum et al., Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β Nature 2012 485 651 655
4. J. C. Chen et al., Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks Cell 2014 159 402 414
5. S. Salloway R. Sperling H. R. Brashear Phase 3 trials of solanezumab and bapineuzumab for Alzheimer's disease N. Engl. J. Med. 2014 370 1460
6. Q. Wang et al., The early diagnosis and monitoring of squamous cell carcinoma via saliva metabolomics Sci. Rep. 2014 4 6802
7. A. Zhang H. Sun X. Wang Saliva metabolomics opens door to biomarker discovery, disease diagnosis, and treatment Appl. Biochem. Biotechnol. 2012 168 1718 1727
8. V. M. Barnes et al., Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease PLoS One 2014 9 e105181
9. J. Zheng R. A. Dixon L. Li Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment Anal. Chem. 2012 84 10802 10811
10. M. Yakob L. Fuentes et al., Salivary biomarkers for detection of oral squamous cell carcinoma-current state and recent advances Current Oral Health Reports 2014 1 133 141
11. T. J. Wang et al., Metabolite profiles and the risk of developing diabetes Nat. Med. 2011 17 448 453
12. A. R. Pfenning et al., Convergent transcriptional specializations in the brains of humans and song-learning birds Science 2014 346 1256846
13. K. L. Poulson-Ellestad et al., Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton Proc. Natl. Acad. Sci. U. S. A. 2014 111 9009 9014
14. G. Kageyama et al., Metabolomics analysis of saliva from patients with primary Sjögren's syndrome Clin. Exp. Immunol. 2015 182 2 149 53
15. A. H. Zhang et al., Ultraperformance liquid chromatography-mass spectrometry based comprehensive metabolomics combined with pattern recognition and network analysis methods for characterization of metabolites and metabolic pathways from biological data sets Anal. Chem. 2013 85 7606 7612
16. A. H. Zhang H. Sun X. J. Wang Recent advances in metabolomics in neurological disease, and future perspectives Anal. Bioanal. Chem. 2013 405 8143 8150
17. M. H. Wiesen F. Farowski M. Feldkötter B. Hoppe C. Müller Liquid chromatography-tandem mass spectrometry method for the quantification of mycophenolic acid and its phenolic glucuronide in saliva and plasma using a standardized saliva collection device J. Chromatogr. A 2012 1241 52 59
18. R. González-Domínguez T. García-Barrera J. L. Gómez-Ariza Using direct infusion mass spectrometry for serum metabolomics in Alzheimer's disease Anal. Bioanal. Chem. 2014 406 7137 7148
19. G. Wang et al., Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment J. Proteome Res. 2014 13 2649 2658
20. R. González-Domínguez A. García T. García-Barrera C. Barbas J. L. Gómez-Ariza Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry Electrophoresis 2014 35 3321 3330
21. I. A. Gorshkova et al., Inhibition of sphingosine-1-phosphate lyase rescues sphingosine kinase-1-knockout phenotype following murine cardiac arrest Life Sci. 2013 93 359 366
22. L. Boon et al., High protein diet induces pericentral glutamate dehydrogenase and ornithine aminotransferase to provide sufficient glutamate for pericentral detoxification of ammonia in rat liver lobules Histochem. Cell Biol. 1999 111 445 452
23. C. Tomlinson et al., Arginine can be synthesized from enteral proline in healthy adult humans J. Nutr. 2011 141 1432 1436
24. T. Fujita et al., Microbial monomers custom-synthesized to build true bio-derived aromatic polymers Appl. Microbiol. Biotechnol. 2013 97 8887 8894
25. R. Cools et al., l-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease Neuropsychopharmacology 2007 32 180 189
26. A. Pinna et al., L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies Exp. Neurol. 2014 253 180 191
27. H. Zhao et al., Quantitative analysis of purine nucleotides indicates that purinosomes increase de novo purine biosynthesis J. Biol. Chem. 2015 290 6705 6713
28. O. Sidorkina M. Saparbaev J. Laval Effects of nitrous acid treatment on the survival and mutagenesis of Escherichia coli cells lacking base excision repair (hypoxanthine-DNA glycosylase-ALK A protein) and/or nucleotide excision repair Mutagenesis 1997 12 23 28
29. M. D. He et al., l-carnitine protects against nickel-induced neurotoxicity by maintaining mitochondrial function in Neuro-2a cells Toxicol. Appl. Pharmacol. 2011 253 38 44