-
1
-
-
84921476692
-
The impact of PNPLA3 (rs738409 C > G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients
-
Brouwer WP, van der Meer AJ, Boonstra A, et al (2015). The impact of PNPLA3 (rs738409 C > G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients. Liver Int, 35, 438-47.
-
(2015)
Liver Int
, vol.35
, pp. 438-447
-
-
Brouwer, W.P.1
van der Meer, A.J.2
Boonstra, A.3
-
2
-
-
79952231921
-
Management of hepatocellular carcinoma: an update
-
Bruix J, Sherman M (2011). Management of hepatocellular carcinoma: an update. Hepatology, 53, 1020-2.
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
3
-
-
30044431801
-
From fat to inflammation
-
Day CP (2006). From fat to inflammation. Gastroenterology, 130, 207-10.
-
(2006)
Gastroenterology
, vol.130
, pp. 207-210
-
-
Day, C.P.1
-
4
-
-
79961186012
-
PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence
-
Falleti E, Fabris C, Cmet S, et al (2011). PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence. Liver Int, 31, 1137-43.
-
(2011)
Liver Int
, vol.31
, pp. 1137-1143
-
-
Falleti, E.1
Fabris, C.2
Cmet, S.3
-
5
-
-
84904353675
-
PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival
-
Friedrich K, WannhoffA, Kattner S, et al (2014). PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival. J Gastroenterol Hepatol, 29, 1477-84.
-
(2014)
J Gastroenterol Hepatol
, vol.29
, pp. 1477-1484
-
-
Friedrich, K.1
Wannhoff, A.2
Kattner, S.3
-
6
-
-
84871706335
-
Risk factors of hepatocellular carcinoma-current status and perspectives
-
Gao J, Xie L, Yang WS, et al (2012). Risk factors of hepatocellular carcinoma-current status and perspectives. Asian Pac J Cancer Prev, 13, 743-52.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 743-752
-
-
Gao, J.1
Xie, L.2
Yang, W.S.3
-
7
-
-
84872421093
-
PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis
-
Guyot E, Sutton A, Rufat P, et al (2013). PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis. J Hepatol, 58, 312-8.
-
(2013)
J Hepatol
, vol.58
, pp. 312-318
-
-
Guyot, E.1
Sutton, A.2
Rufat, P.3
-
8
-
-
77949895032
-
A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
-
He S, McPhaul C, Li JZ, et al (2010). A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem, 285, 6706-15.
-
(2010)
J Biol Chem
, vol.285
, pp. 6706-6715
-
-
He, S.1
McPhaul, C.2
Li, J.Z.3
-
9
-
-
77952409634
-
A feed-forward loop amplifies nutritional regulation of PNPLA3
-
Huang Y, He S, Li JZ, et al (2010). A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc Natl Acad Sci U S A, 107, 7892-7.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7892-7897
-
-
Huang, Y.1
He, S.2
Li, J.Z.3
-
10
-
-
10344262633
-
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities
-
Jenkins CM, Mancuso DJ, Yan W, et al (2004). Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J Biol Chem, 279, 48968-75.
-
(2004)
J Biol Chem
, vol.279
, pp. 48968-48975
-
-
Jenkins, C.M.1
Mancuso, D.J.2
Yan, W.3
-
11
-
-
79959762483
-
Evaluation of the association studies of single nucleotide polymorphisms and hepatocellular carcinoma: a systematic review
-
Jin F, Xiong WJ, Jing JC, et al (2011). Evaluation of the association studies of single nucleotide polymorphisms and hepatocellular carcinoma: a systematic review. J Cancer Res Clin Oncol, 137, 1095-104.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, pp. 1095-1104
-
-
Jin, F.1
Xiong, W.J.2
Jing, J.C.3
-
12
-
-
84902688337
-
Carriage of the PNPLA3 rs738409 C > G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma
-
Liu YL, Patman GL, Leathart JB, et al (2014). Carriage of the PNPLA3 rs738409 C > G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. J Hepatol, 61, 75-81.
-
(2014)
J Hepatol
, vol.61
, pp. 75-81
-
-
Liu, Y.L.1
Patman, G.L.2
Leathart, J.B.3
-
13
-
-
44449085884
-
Design and endpoints of clinical trials in hepatocellular carcinoma
-
Llovet JM, Di Bisceglie AM, Bruix J, et al (2008). Design and endpoints of clinical trials in hepatocellular carcinoma. J Natl Cancer Inst, 100, 698-711.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 698-711
-
-
Llovet, J.M.1
Di Bisceglie, A.M.2
Bruix, J.3
-
14
-
-
84920385208
-
Pathogenesis of hepatocellular carcinoma according to aetiology
-
Nault JC (2014). Pathogenesis of hepatocellular carcinoma according to aetiology. Best Pract Res Clin Gastroenterol, 28, 937-47.
-
(2014)
Best Pract Res Clin Gastroenterol
, vol.28
, pp. 937-947
-
-
Nault, J.C.1
-
15
-
-
80455174482
-
The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis
-
Nischalke HD, Berger C, Luda C, et al (2011). The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis. PLoS One, 6, 27087.
-
(2011)
PLoS One
, vol.6
, pp. 27087
-
-
Nischalke, H.D.1
Berger, C.2
Luda, C.3
-
16
-
-
10744227418
-
The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients
-
Patton HM, Patel K, Behling C, et al (2004). The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol, 40, 484-90.
-
(2004)
J Hepatol
, vol.40
, pp. 484-490
-
-
Patton, H.M.1
Patel, K.2
Behling, C.3
-
17
-
-
84896895656
-
Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function
-
Pingitore P, Pirazzi C, Mancina RM, et al (2014). Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function. Biochim Biophys Acta, 1841, 574-80.
-
(2014)
Biochim Biophys Acta
, vol.1841
, pp. 574-580
-
-
Pingitore, P.1
Pirazzi, C.2
Mancina, R.M.3
-
18
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
Romeo S, Kozlitina J, Xing C, et al (2008). Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet, 40, 1461-5.
-
(2008)
Nat Genet
, vol.40
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Xing, C.3
-
19
-
-
0033933140
-
Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3
-
Rubbia-Brandt L, Quadri R, Abid K, et al (2000). Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol, 33, 106-15.
-
(2000)
J Hepatol
, vol.33
, pp. 106-115
-
-
Rubbia-Brandt, L.1
Quadri, R.2
Abid, K.3
-
20
-
-
84930766891
-
PNPLA3 Gene polymorphism is associated with predisposition to and severity of alcoholic liver disease
-
Salameh H, RaffE, Erwin A, et al (2015). PNPLA3 Gene polymorphism is associated with predisposition to and severity of alcoholic liver disease. The American journal of gastroenterology, 110, 846-56.
-
(2015)
The American journal of gastroenterology
, vol.110
, pp. 846-856
-
-
Salameh, H.1
Raff, E.2
Erwin, A.3
-
21
-
-
84907877530
-
Impact of PNPLA3 polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection
-
Sato M, Kato N, Tateishi R, et al (2014). Impact of PNPLA3 polymorphisms on the development of hepatocellular carcinoma in patients with chronic hepatitis C virus infection. Hepatol Res, 44, 137-44.
-
(2014)
Hepatol Res
, vol.44
, pp. 137-144
-
-
Sato, M.1
Kato, N.2
Tateishi, R.3
-
22
-
-
84895792814
-
The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis
-
Singal AG, Manjunath H, Yopp AC, et al (2014). The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: a meta-analysis. The American journal of gastroenterology, 109, 325-34.
-
(2014)
The American journal of gastroenterology
, vol.109
, pp. 325-334
-
-
Singal, A.G.1
Manjunath, H.2
Yopp, A.C.3
-
23
-
-
84920955177
-
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
-
Smagris E, BasuRay S, Li J, et al (2015). Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis. Hepatology, 61, 108-18.
-
(2015)
Hepatology
, vol.61
, pp. 108-118
-
-
Smagris, E.1
BasuRay, S.2
Li, J.3
-
24
-
-
69249111667
-
A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity
-
Sookoian S, Castano GO, Burgueno AL, et al (2009). A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity. J Lipid Res, 50, 2111-6.
-
(2009)
J Lipid Res
, vol.50
, pp. 2111-2116
-
-
Sookoian, S.1
Castano, G.O.2
Burgueno, A.L.3
-
25
-
-
84880339027
-
The KIF1B (rs17401966) single nucleotide polymorphism is not associated with the development of HBV-related hepatocellular carcinoma in Thai patients
-
Sopipong W, Tangkijvanich P, Payungporn S, et al (2013). The KIF1B (rs17401966) single nucleotide polymorphism is not associated with the development of HBV-related hepatocellular carcinoma in Thai patients. Asian Pac J Cancer Prev, 14, 2865-9.
-
(2013)
Asian Pac J Cancer Prev
, vol.14
, pp. 2865-2869
-
-
Sopipong, W.1
Tangkijvanich, P.2
Payungporn, S.3
-
26
-
-
78751536418
-
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
-
Stickel F, Buch S, Lau K, et al (2011). Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology, 53, 86-95.
-
(2011)
Hepatology
, vol.53
, pp. 86-95
-
-
Stickel, F.1
Buch, S.2
Lau, K.3
-
27
-
-
84878786093
-
The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis
-
Takeuchi Y, Ikeda F, Moritou Y, et al (2013). The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis. J Gastroenterol, 48, 405-12.
-
(2013)
J Gastroenterol
, vol.48
, pp. 405-412
-
-
Takeuchi, Y.1
Ikeda, F.2
Moritou, Y.3
-
28
-
-
0032926913
-
Association of hepatitis viruses with hepatocellular carcinoma in Thailand
-
Tangkijvanich P, Hirsch P, Theamboonlers A, et al (1999). Association of hepatitis viruses with hepatocellular carcinoma in Thailand. J Gastroenterol, 34, 227-33.
-
(1999)
J Gastroenterol
, vol.34
, pp. 227-233
-
-
Tangkijvanich, P.1
Hirsch, P.2
Theamboonlers, A.3
-
29
-
-
84859147155
-
PNPLA3 (rs738409 C > G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis
-
Trepo E, Guyot E, Ganne-Carrie N, et al (2012). PNPLA3 (rs738409 C > G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis. Hepatology, 55, 1307-8.
-
(2012)
Hepatology
, vol.55
, pp. 1307-1308
-
-
Trepo, E.1
Guyot, E.2
Ganne-Carrie, N.3
-
30
-
-
84901608440
-
Association between the PNPLA3 (rs738409 C > G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data
-
Trepo E, Nahon P, Bontempi G, et al (2014). Association between the PNPLA3 (rs738409 C > G) variant and hepatocellular carcinoma: Evidence from a meta-analysis of individual participant data. Hepatology, 59, 2170-7.
-
(2014)
Hepatology
, vol.59
, pp. 2170-2177
-
-
Trepo, E.1
Nahon, P.2
Bontempi, G.3
-
31
-
-
79959554057
-
Impact of patatinlike phospholipase-3 (rs738409 C > G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C
-
Trepo E, Pradat P, PotthoffA, et al (2011). Impact of patatinlike phospholipase-3 (rs738409 C > G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C. Hepatology, 54, 60-9.
-
(2011)
Hepatology
, vol.54
, pp. 60-69
-
-
Trepo, E.1
Pradat, P.2
Potthoff, A.3
-
32
-
-
84885402417
-
PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma
-
Valenti L, Motta BM, Soardo G, et al (2013). PNPLA3 I148M polymorphism, clinical presentation, and survival in patients with hepatocellular carcinoma. PLoS One, 8, 75982.
-
(2013)
PLoS One
, vol.8
, pp. 75982
-
-
Valenti, L.1
Motta, B.M.2
Soardo, G.3
-
33
-
-
84884978594
-
Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B
-
Vigano M, Valenti L, Lampertico P, et al (2013). Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B. Hepatology, 58, 1245-52.
-
(2013)
Hepatology
, vol.58
, pp. 1245-1252
-
-
Vigano, M.1
Valenti, L.2
Lampertico, P.3
-
34
-
-
53049090077
-
Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes
-
Yuan X, Waterworth D, Perry JR, et al (2008). Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. Am J Hum Genet, 83, 520-8.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 520-528
-
-
Yuan, X.1
Waterworth, D.2
Perry, J.R.3
-
35
-
-
84942194270
-
Patatin-Like Phospholipase Domain-Containing 3 I148M variant is associated with liver steatosis and fat distribution in Chronic Hepatitis B
-
Zampino R, Coppola N, Cirillo G, et al (2015). Patatin-Like Phospholipase Domain-Containing 3 I148M variant is associated with liver steatosis and fat distribution in Chronic Hepatitis B. Dig Dis Sci.
-
(2015)
Dig Dis Sci.
-
-
Zampino, R.1
Coppola, N.2
Cirillo, G.3
|