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Volumn 109, Issue 3, 2014, Pages 325-334

The effect of PNPLA3 on fibrosis progression and development of hepatocellular carcinoma: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER PROGNOSIS; CANCER RISK; CAUCASIAN; DISEASE COURSE; DISEASE SEVERITY; GENE; GENE MUTATION; GENETIC ASSOCIATION; GENOTYPE; HUMAN; LIVER CELL CARCINOMA; LIVER DISEASE; LIVER FIBROSIS; META ANALYSIS (TOPIC); OUTCOME ASSESSMENT; PNPLA3 GENE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW;

EID: 84895792814     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2013.476     Document Type: Article
Times cited : (276)

References (60)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-76.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 2
    • 7044272630 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
    • Fattovich G, Stroff olini T, Zagni I et al. Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology 2004; 127: S35-50.
    • (2004) Gastroenterology , vol.127
    • Fattovich, G.1    Stroffolini, T.2    Zagni, I.3
  • 3
    • 84874391749 scopus 로고    scopus 로고
    • Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma
    • Nishida N, Kudo M. Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma. Oncology 2013; 84 (Suppl 1): 93-7.
    • (2013) Oncology , vol.84 , Issue.SUPPL. 1 , pp. 93-97
    • Nishida, N.1    Kudo, M.2
  • 4
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • Romeo S, Kozlitina J, Xing C et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2008; 40: 1461-5.
    • (2008) Nat Genet , vol.40 , pp. 1461-1465
    • Romeo, S.1    Kozlitina, J.2    Xing, C.3
  • 5
    • 79957462315 scopus 로고    scopus 로고
    • Meta-analysis of the influence of I148 M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
    • Sookoian S, Pirola CJ. Meta-analysis of the influence of I148 M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology 2011; 53: 1883-94.
    • (2011) Hepatology , vol.53 , pp. 1883-1894
    • Sookoian, S.1    Pirola, C.J.2
  • 6
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • W64
    • Moher D, Liberati A, Tetzlaff J et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151: 264-9, W64.
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 8
    • 84873975790 scopus 로고    scopus 로고
    • Are healthcare workers'intentions to vaccinate related to their knowledge, beliefs and attitudes? A systematic review
    • Herzog R, Alvarez-Pasquin MJ, Diaz C et al. Are healthcare workers'intentions to vaccinate related to their knowledge, beliefs and attitudes? A systematic review. BMC Public Health 2013; 13: 154.
    • (2013) BMC Public Health , vol.13 , pp. 154
    • Herzog, R.1    Alvarez-Pasquin, M.J.2    Diaz, C.3
  • 9
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Th ompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-58.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 10
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in metaanalyses
    • Higgins JP, Th ompson SG, Deeks JJ et al. Measuring inconsistency in metaanalyses. BMJ 2003; 327: 557-60.
    • (2003) BMJ , vol.327 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3
  • 11
    • 0034916079 scopus 로고    scopus 로고
    • A sensitivity analysis for publication bias in systematic reviews
    • Copas JB, Shi JQ. A sensitivity analysis for publication bias in systematic reviews. Stat Methods Med Res 2001; 10: 251-65.
    • (2001) Stat Methods Med Res , vol.10 , pp. 251-265
    • Copas, J.B.1    Shi, J.Q.2
  • 12
    • 0035961567 scopus 로고    scopus 로고
    • A comparison of methods to detect publication bias in meta-analysis
    • Macaskill P, Walter SD, Irwig L. A comparison of methods to detect publication bias in meta-analysis. Stat Med 2001; 20: 641-54.
    • (2001) Stat Med , vol.20 , pp. 641-654
    • Macaskill, P.1    Walter, S.D.2    Irwig, L.3
  • 13
    • 84895784829 scopus 로고    scopus 로고
    • A composite score including BMI, liver stiff ness, and rs738409 PNPLA3 genotype might spare liver biopsies to most NAFLD patients maintaining 95% diagnostic accuracy
    • Burlone M, Rossini A, Magri A et al. A composite score including BMI, liver stiff ness, and rs738409 PNPLA3 genotype might spare liver biopsies to most NAFLD patients maintaining 95% diagnostic accuracy. Hepatology 2012; 56: 885A.
    • (2012) Hepatology , vol.56
    • Burlone, M.1    Rossini, A.2    Magri, A.3
  • 14
    • 84869505814 scopus 로고    scopus 로고
    • The interaction of rs738409, obesity, and alcohol: A population-based autopsy study
    • Dunn W, Zeng Z, O'Neil M et al. The interaction of rs738409, obesity, and alcohol: a population-based autopsy study. Am J Gastroenterol 2012; 107: 1668-74.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1668-1674
    • Dunn, W.1    Zeng, Z.2    O'Neil, M.3
  • 15
    • 84884909122 scopus 로고    scopus 로고
    • Interactions of allelic variance of PNPLA3 with non genetic factors in predicting NASH and non-hepatic complications of severe obesity
    • Guichelaar M, Gawrieh S, Olivier M et al. Interactions of allelic variance of PNPLA3 with non genetic factors in predicting NASH and non-hepatic complications of severe obesity. Obesity 2013; 21: 1935-41.
    • (2013) Obesity , vol.21 , pp. 1935-1941
    • Guichelaar, M.1    Gawrieh, S.2    Olivier, M.3
  • 16
    • 78650336759 scopus 로고    scopus 로고
    • Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease
    • Hotta K, Yoneda M, Hyogo H et al. Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease. BMC Med Genet 2010; 11: 172.
    • (2010) BMC Med Genet , vol.11 , pp. 172
    • Hotta, K.1    Yoneda, M.2    Hyogo, H.3
  • 17
    • 79959562237 scopus 로고    scopus 로고
    • Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: Non-invasive elastography-based study in chronic liver disease
    • Krawczyk M, Grunhage F, Zimmer V et al. Variant adiponutrin (PNPLA3) represents a common fibrosis risk gene: non-invasive elastography-based study in chronic liver disease. J Hepatol 2011; 55: 299-306.
    • (2011) J Hepatol , vol.55 , pp. 299-306
    • Krawczyk, M.1    Grunhage, F.2    Zimmer, V.3
  • 18
    • 84864675463 scopus 로고    scopus 로고
    • Genetic polymorphism in cyclooxygenase-2 promoter aff ects hepatic inflammation and fibrosis in patients with chronic hepatitis C
    • Miyashita M, Ito T, Sakaki M et al. Genetic polymorphism in cyclooxygenase-2 promoter aff ects hepatic inflammation and fibrosis in patients with chronic hepatitis C. J Viral Hepat 2012; 19: 608-14.
    • (2012) J Viral Hepat , vol.19 , pp. 608-614
    • Miyashita, M.1    Ito, T.2    Sakaki, M.3
  • 19
    • 84860389885 scopus 로고    scopus 로고
    • Distinct, alcohol-modulated Effects of PNPLA3 genotype on progression of chronic hepatitis C
    • Müller T, Buch S, Berg T et al. Distinct, alcohol-modulated Effects of PNPLA3 genotype on progression of chronic hepatitis C. J Hepatol 2011; 55: 732-3.
    • (2011) J Hepatol , vol.55 , pp. 732-733
    • Müller, T.1    Buch, S.2    Berg, T.3
  • 20
    • 84868157974 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection
    • Patin E, Kutalik Z, Guergnon J et al. Genome-wide association study identifies variants associated with progression of liver fibrosis from HCV infection. Gastroenterology 2012; 143: 1244-1252.e2.
    • (2012) Gastroenterology , vol.143
    • Patin, E.1    Kutalik, Z.2    Guergnon, J.3
  • 21
    • 84895792578 scopus 로고    scopus 로고
    • Influence of PNPLA3 SNP on hepatic steatosis and fibrosis progression in HIV-HCV coinfected patients
    • Payer B, Reiberger T, Stift J et al. Influence of PNPLA3 SNP on hepatic steatosis and fibrosis progression in HIV-HCV coinfected patients. J Hepatol 2012; 56: S356.
    • (2012) J Hepatol , vol.56
    • Payer, B.1    Reiberger, T.2    Stift, J.3
  • 22
    • 77956636268 scopus 로고    scopus 로고
    • The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease
    • Rotman Y, Koh C, Zmuda JM et al. The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. Hepatology 2010; 52: 894-903.
    • (2010) Hepatology , vol.52 , pp. 894-903
    • Rotman, Y.1    Koh, C.2    Zmuda, J.M.3
  • 23
    • 84895798121 scopus 로고    scopus 로고
    • PNPLA3 polymorphism is patients with chronic hepatitis C-impact on steatosis, fibrosis, and treatment response
    • Stattermayer A, Rutter K, Hofer H et al. PNPLA3 polymorphism is patients with chronic hepatitis C-impact on steatosis, fibrosis, and treatment response. J Hepatol 2011; 54: S194.
    • (2011) J Hepatol , vol.54
    • Stattermayer, A.1    Rutter, K.2    Hofer, H.3
  • 24
    • 78751536418 scopus 로고    scopus 로고
    • Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians
    • Stickel F, Buch S, Lau K et al. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology 2011; 53: 86-95.
    • (2011) Hepatology , vol.53 , pp. 86-95
    • Stickel, F.1    Buch, S.2    Lau, K.3
  • 25
    • 79959561798 scopus 로고    scopus 로고
    • Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease
    • Trepo E, Gustot T, Degre D et al. Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease. J Hepatol 2011; 55: 906-12.
    • (2011) J Hepatol , vol.55 , pp. 906-912
    • Trepo, E.1    Gustot, T.2    Degre, D.3
  • 26
    • 79959554057 scopus 로고    scopus 로고
    • Impact of patatin-like phospholipase-3 (rs738409 C > G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C
    • Trepo E, Pradat P, Potthoff A et al. Impact of patatin-like phospholipase-3 (rs738409 C > G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C. Hepatology 2011; 54: 60-9.
    • (2011) Hepatology , vol.54 , pp. 60-69
    • Trepo, E.1    Pradat, P.2    Potthoff, A.3
  • 27
    • 84863108828 scopus 로고    scopus 로고
    • Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis
    • Valenti L, Maggioni P, Piperno A et al. Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis. World J Gastroenterol 2012; 18: 2813-20.
    • (2012) World J Gastroenterol , vol.18 , pp. 2813-2820
    • Valenti, L.1    Maggioni, P.2    Piperno, A.3
  • 28
    • 81255198296 scopus 로고    scopus 로고
    • The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver
    • Valenti L, Nobili V, Al-Serri A et al. The APOC3 T-455C and C-482T promoter region polymorphisms are not associated with the severity of liver damage independently of PNPLA3 I148M genotype in patients with nonalcoholic fatty liver. J Hepatol 2011; 55: 1409-14.
    • (2011) J Hepatol , vol.55 , pp. 1409-1414
    • Valenti, L.1    Nobili, V.2    Al-Serri, A.3
  • 29
    • 79952222716 scopus 로고    scopus 로고
    • Patatin-like phospholipase domaincontaining 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C
    • Valenti L, Rumi M, Galmozzi E et al. Patatin-like phospholipase domaincontaining 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C. Hepatology 2011; 53: 791-9.
    • (2011) Hepatology , vol.53 , pp. 791-799
    • Valenti, L.1    Rumi, M.2    Galmozzi, E.3
  • 30
    • 84884978594 scopus 로고    scopus 로고
    • PNPLA3 I148M aff ects liver steatosis in patients with chronic hepatitis B
    • Vigano M, Valenti L, Lampertico P et al. PNPLA3 I148M aff ects liver steatosis in patients with chronic hepatitis B. Hepatology 2013; 58: 1245-52.
    • (2013) Hepatology , vol.58 , pp. 1245-1252
    • Vigano, M.1    Valenti, L.2    Lampertico, P.3
  • 31
    • 84895823188 scopus 로고    scopus 로고
    • The PNPLA3 I148M mutation significantly increases the risk of developing alcohol-related cirrhosis in alcohol dependent individuals
    • Way M, McQuillin A, Gurling H et al. The PNPLA3 I148M mutation significantly increases the risk of developing alcohol-related cirrhosis in alcohol dependent individuals. J Hepatol 2013; 58: S563.
    • (2013) J Hepatol , vol.58
    • Way, M.1    McQuillin, A.2    Gurling, H.3
  • 32
    • 84862765487 scopus 로고    scopus 로고
    • A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease
    • Zain SM, Mohamed R, Mahadeva S et al. A multi-ethnic study of a PNPLA3 gene variant and its association with disease severity in non-alcoholic fatty liver disease. Hum Genet 2012; 131: 1145-52.
    • (2012) Hum Genet , vol.131 , pp. 1145-1152
    • Zain, S.M.1    Mohamed, R.2    Mahadeva, S.3
  • 33
    • 84879798869 scopus 로고    scopus 로고
    • Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C
    • Zampino R, Coppola N, Cirillo G et al. Abdominal fat interacts with PNPLA3 I148M, but not with the APOC3 variant in the pathogenesis of liver steatosis in chronic hepatitis C. J Viral Hepatitis 2013; 20: 517-23.
    • (2013) J Viral Hepatitis , vol.20 , pp. 517-523
    • Zampino, R.1    Coppola, N.2    Cirillo, G.3
  • 34
    • 84895822900 scopus 로고    scopus 로고
    • The impact of genetic variability of patatin-like phospholipase domain-containing 3 gene on histological progression of non-alcoholic fatty liver disease: A crosssectional and longitudinal follow-up study
    • Idilman R, Keskin O, Karatayli SC et al. The impact of genetic variability of patatin-like phospholipase domain-containing 3 gene on histological progression of non-alcoholic fatty liver disease: A crosssectional and longitudinal follow-up study. Hepatology 2012; 56: 884A-5A.
    • (2012) Hepatology , vol.56
    • Idilman, R.1    Keskin, O.2    Karatayli, S.C.3
  • 35
    • 84866182469 scopus 로고    scopus 로고
    • PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection
    • Rembeck K, Maglio C, Lagging M et al. PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection. BMC Med Genet 2012; 13: 82.
    • (2012) BMC Med Genet , vol.13 , pp. 82
    • Rembeck, K.1    Maglio, C.2    Lagging, M.3
  • 36
    • 84865144054 scopus 로고    scopus 로고
    • Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C
    • Stattermayer AF, Rutter K, Beinhardt S et al. Association of the IL28B genotype with insulin resistance in patients with chronic hepatitis C. J Hepatol 2012; 57: 492-8.
    • (2012) J Hepatol , vol.57 , pp. 492-498
    • Stattermayer, A.F.1    Rutter, K.2    Beinhardt, S.3
  • 37
    • 84866438865 scopus 로고    scopus 로고
    • Noninvasive assessment of nonalcoholic fatty liver disease in obese or overweight patients
    • quiz e87
    • Francque SM, Verrijken A, Mertens I et al. Noninvasive assessment of nonalcoholic fatty liver disease in obese or overweight patients. Clin Gastroenterol Hepatol 2012; 10: 1162-8; quiz e87.
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 1162-1168
    • Francque, S.M.1    Verrijken, A.2    Mertens, I.3
  • 38
    • 84885381567 scopus 로고    scopus 로고
    • A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population
    • Verrijken A, Beckers S, Francque S et al. A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population. Obesity 2013; 21: 2138-45.
    • (2013) Obesity , vol.21 , pp. 2138-2145
    • Verrijken, A.1    Beckers, S.2    Francque, S.3
  • 39
    • 73349111259 scopus 로고    scopus 로고
    • Variant in PNPLA3 is associated with alcoholic liver disease
    • Tian C, Stokowski RP, Kershenobich D et al. Variant in PNPLA3 is associated with alcoholic liver disease. Nat Genet 2010; 42: 21-3.
    • (2010) Nat Genet , vol.42 , pp. 21-23
    • Tian, C.1    Stokowski, R.P.2    Kershenobich, D.3
  • 40
    • 84866409701 scopus 로고    scopus 로고
    • The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection
    • Clark PJ, Th ompson AJ, Zhu Q et al. The association of genetic variants with hepatic steatosis in patients with genotype 1 chronic hepatitis C infection. Dig Dis Sci 2012; 57: 2213-21.
    • (2012) Dig Dis Sci , vol.57 , pp. 2213-2221
    • Clark, P.J.1    Thompson, A.J.2    Zhu, Q.3
  • 41
    • 79955085671 scopus 로고    scopus 로고
    • Patatin-like phospholipase domain containing 3 sequence variant and hepatocellular carcinoma
    • Corradini SG, Burza MA, Molinaro A et al. Patatin-like phospholipase domain containing 3 sequence variant and hepatocellular carcinoma. Hepatology 2011; 53: 1776; author reply 1777.
    • (2011) Hepatology , vol.53 , pp. 1776-1777
    • Corradini, S.G.1    Burza, M.A.2    Molinaro, A.3
  • 42
    • 79961186012 scopus 로고    scopus 로고
    • PNPLA3 rs738409C/G polymorphism in cirrhosis: Relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence
    • Falleti E, Fabris C, Cmet S et al. PNPLA3 rs738409C/G polymorphism in cirrhosis: relationship with the aetiology of liver disease and hepatocellular carcinoma occurrence. Liver Int 2011; 31: 1137-43.
    • (2011) Liver Int , vol.31 , pp. 1137-1143
    • Falleti, E.1    Fabris, C.2    Cmet, S.3
  • 43
    • 84872421093 scopus 로고    scopus 로고
    • PNPLA3 rs738409 hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis
    • Guyot E, Sutton A, Rufat P et al. PNPLA3 rs738409, hepatocellular carcinoma occurrence and risk model prediction in patients with cirrhosis. J Hepatol 2013; 58: 312-8.
    • (2013) J Hepatol , vol.58 , pp. 312-318
    • Guyot, E.1    Sutton, A.2    Rufat, P.3
  • 44
    • 84895785905 scopus 로고    scopus 로고
    • PNPLA3 rs738409 GG homozygote status is associated with increased risk of hepatocellular carcinoma in cirrhotic patients
    • Hamza S, Petit J, Masson D et al. PNPLA3 rs738409 GG homozygote status is associated with increased risk of hepatocellular carcinoma in cirrhotic patients. J Hepatol 2012; 56: S281.
    • (2012) J Hepatol , vol.56
    • Hamza, S.1    Petit, J.2    Masson, D.3
  • 45
    • 84887320571 scopus 로고    scopus 로고
    • Carriage of PNPLA3 I148M is associated wtih an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma
    • Liu Y, Patman G, Lethart J et al. Carriage of PNPLA3 I148M is associated wtih an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. J Hepatol 2013; 58: S516.
    • (2013) J Hepatol , vol.58
    • Liu, Y.1    Patman, G.2    Lethart, J.3
  • 46
    • 80455174482 scopus 로고    scopus 로고
    • The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis
    • Nischalke HD, Berger C, Luda C et al. The PNPLA3 rs738409 148M/M genotype is a risk factor for liver cancer in alcoholic cirrhosis but shows no or weak association in hepatitis C cirrhosis. PLoS ONE 2011; 6: e27087.
    • (2011) PLoS ONE , vol.6
    • Nischalke, H.D.1    Berger, C.2    Luda, C.3
  • 47
    • 84878786093 scopus 로고    scopus 로고
    • The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis
    • Takeuchi Y, Ikeda F, Moritou Y et al. The impact of patatin-like phospholipase domain-containing protein 3 polymorphism on hepatocellular carcinoma prognosis. J Gastroenterol 2013; 48: 405-12.
    • (2013) J Gastroenterol , vol.48 , pp. 405-412
    • Takeuchi, Y.1    Ikeda, F.2    Moritou, Y.3
  • 48
    • 84859147155 scopus 로고    scopus 로고
    • PNPLA3 (rs738409 C > G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis
    • Trepo E, Guyot E, Ganne-Carrie N et al. PNPLA3 (rs738409 C > G) is a common risk variant associated with hepatocellular carcinoma in alcoholic cirrhosis. Hepatology 2012; 55: 1307-8.
    • (2012) Hepatology , vol.55 , pp. 1307-1308
    • Trepo, E.1    Guyot, E.2    Ganne-Carrie, N.3
  • 49
    • 84868304332 scopus 로고    scopus 로고
    • PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals
    • Burza MA, Pirazzi C, Maglio C et al. PNPLA3 I148M (rs738409) genetic variant is associated with hepatocellular carcinoma in obese individuals. Dig Liver Dis 2012; 44: 1037-41.
    • (2012) Dig Liver Dis , vol.44 , pp. 1037-1041
    • Burza, M.A.1    Pirazzi, C.2    Maglio, C.3
  • 50
    • 84881552570 scopus 로고    scopus 로고
    • I148M PNPLA3 polymorphism is associated with clinical features in patients wtih hepatocellular carcinoma
    • Valenti L, Motta B, Soardo G et al. I148M PNPLA3 polymorphism is associated with clinical features in patients wtih hepatocellular carcinoma. J Hepatol 2012; 56: S129.
    • (2012) J Hepatol , vol.56
    • Valenti, L.1    Motta, B.2    Soardo, G.3
  • 51
    • 77949895032 scopus 로고    scopus 로고
    • A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis
    • He S, McPhaul C, Li JZ et al. A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. J Biol Chem 2010; 285: 6706-15.
    • (2010) J Biol Chem , vol.285 , pp. 6706-6715
    • He, S.1    McPhaul, C.2    Li, J.Z.3
  • 52
    • 80054806707 scopus 로고    scopus 로고
    • Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease
    • Huang Y, Cohen JC, Hobbs HH. Expression and characterization of a PNPLA3 protein isoform (I148M) associated with nonalcoholic fatty liver disease. J Biol Chem 2011; 286: 37085-93.
    • (2011) J Biol Chem , vol.286 , pp. 37085-37093
    • Huang, Y.1    Cohen, J.C.2    Hobbs, H.H.3
  • 53
    • 84881559322 scopus 로고    scopus 로고
    • PNPLA3 I148M variant and hepatocellular carcinoma: A common genetic variant for a rare disease
    • Valenti L, Dongiovanni P, Ginanni Corradini S et al. PNPLA3 I148M variant and hepatocellular carcinoma: A common genetic variant for a rare disease. Dig Liver Dis 2013; 45: 619-24.
    • (2013) Dig Liver Dis , vol.45 , pp. 619-624
    • Valenti, L.1    Dongiovanni, P.2    Ginanni Corradini, S.3
  • 54
    • 84861188878 scopus 로고    scopus 로고
    • Implications of PNPLA3 polymorphism in chronic hepatitis C patients receiving peginterferon plus ribavirin
    • Valenti L, Aghemo A, Stattermayer AF et al. Implications of PNPLA3 polymorphism in chronic hepatitis C patients receiving peginterferon plus ribavirin. Aliment Pharmacol Th er 2013; 35: 1434-42.
    • (2013) Aliment Pharmacol Th Er , vol.35 , pp. 1434-1442
    • Valenti, L.1    Aghemo, A.2    Stattermayer, A.F.3
  • 55
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection
    • Starley BQ, Calcagno CJ, Harrison SA. Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 2010; 51: 1820-32.
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 56
    • 84887246574 scopus 로고    scopus 로고
    • Machine learning algorithms outperform conventional regression models in predicting development of hepatocellular carcinoma
    • Singal AG, Mukherjee A, Elmunzer BJ et al. Machine learning algorithms outperform conventional regression models in predicting development of hepatocellular carcinoma. Am J Gastroenterol 2013; 108: 1723-30.
    • (2013) Am J Gastroenterol , vol.108 , pp. 1723-1730
    • Singal, A.G.1    Mukherjee, A.2    Elmunzer, B.J.3
  • 57
    • 84875224556 scopus 로고    scopus 로고
    • Improving hepatocellular carcinoma screening: Applying lessons from colorectal cancer screening
    • Singal AG, Tiro JA, Gupta S. Improving hepatocellular carcinoma screening: applying lessons from colorectal cancer screening. Clin Gastroenterol Hepatol 2013; 11: 472-7.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 472-477
    • Singal, A.G.1    Tiro, J.A.2    Gupta, S.3
  • 58
    • 84862644081 scopus 로고    scopus 로고
    • Utilization of hepatocellular carcinoma surveillance among American patients: A systematic review
    • Singal AG, Yopp A, C SS et al. Utilization of hepatocellular carcinoma surveillance among American patients: a systematic review. J Gen Intern Med 2012; 27: 861-7.
    • (2012) J Gen Intern Med , vol.27 , pp. 861-867
    • Singal, A.G.1    Yopp, A.2    Ss, C.3
  • 59
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • Browning JD, Szczepaniak LS, Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004; 40: 1387-95.
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3
  • 60
    • 12844280471 scopus 로고    scopus 로고
    • Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease
    • Weston SR, Leyden W, Murphy R et al. Racial and ethnic distribution of nonalcoholic fatty liver in persons with newly diagnosed chronic liver disease. Hepatology 2005; 41: 372-9.
    • (2005) Hepatology , vol.41 , pp. 372-379
    • Weston, S.R.1    Leyden, W.2    Murphy, R.3


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