-
2
-
-
80054686286
-
Tumor metastasis: Molecular insights and evolving paradigms
-
Valastyan S and Weinberg RA: Tumor metastasis: Molecular insights and evolving paradigms. Cell 147: 275-292, 2011.
-
(2011)
Cell
, vol.147
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
3
-
-
84882574569
-
Screening and identification of significant genes related to tumor metastasis and PSMA in prostate cancer using microarray analysis
-
Xu L, Wang Z, Li XF, He X, Guan LL, Tuo JL, Wang Y, Luo Y, Zhong HL, Qiu SP, et al: Screening and identification of significant genes related to tumor metastasis and PSMA in prostate cancer using microarray analysis. Oncol Rep 30: 1920-1928, 2013.
-
(2013)
Oncol Rep
, vol.30
, pp. 1920-1928
-
-
Xu, L.1
Wang, Z.2
Li, X.F.3
He, X.4
Guan, L.L.5
Tuo, J.L.6
Wang, Y.7
Luo, Y.8
Zhong, H.L.9
Qiu, S.P.10
-
4
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villén J, Shin C, Camargo FD, Gygi SP and Bartel DP: The impact of microRNAs on protein output. Nature 455: 64-71, 2008.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villén, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
5
-
-
84936986357
-
Role of microRNAs in prostate cancer pathogenesis
-
Wang YL, Wu S, Jiang B, Yin FF, Zheng SS and Hou SC: Role of microRNAs in prostate cancer pathogenesis. Clin Genitourin Cancer 13: 261-270, 2015.
-
(2015)
Clin Genitourin Cancer
, vol.13
, pp. 261-270
-
-
Wang, Y.L.1
Wu, S.2
Jiang, B.3
Yin, F.F.4
Zheng, S.S.5
Hou, S.C.6
-
6
-
-
55549114664
-
The MIR-15a-MIR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities
-
Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L, D'Urso L, Pagliuca A, Biffoni M, Labbaye C, et al: The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities. Nat Med 14: 1271-1277, 2008.
-
(2008)
Nat Med
, vol.14
, pp. 1271-1277
-
-
Bonci, D.1
Coppola, V.2
Musumeci, M.3
Addario, A.4
Giuffrida, R.5
Memeo, L.6
D'Urso, L.7
Pagliuca, A.8
Biffoni, M.9
Labbaye, C.10
-
7
-
-
84875807408
-
Upregulation of MIR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer
-
Wu Z, He B, He J and Mao X: Upregulation of miR-153 promotes cell proliferation via downregulation of the PTEN tumor suppressor gene in human prostate cancer. Prostate 73: 596-604, 2013.
-
(2013)
Prostate
, vol.73
, pp. 596-604
-
-
Wu, Z.1
He, B.2
He, J.3
Mao, X.4
-
8
-
-
84892579226
-
MIR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration
-
Lewis H, Lance R, Troyer D, Beydoun H, Hadley M, Orians J, Benzine T, Madric K, Semmes OJ, Drake R, et al: miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration. Cell Cycle 13: 227-239, 2014.
-
(2014)
Cell Cycle
, vol.13
, pp. 227-239
-
-
Lewis, H.1
Lance, R.2
Troyer, D.3
Beydoun, H.4
Hadley, M.5
Orians, J.6
Benzine, T.7
Madric, K.8
Semmes, O.J.9
Drake, R.10
-
9
-
-
84879672675
-
MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer
-
Verdoodt B, Neid M, Vogt M, Kuhn V, Liffers ST, Palisaar RJ, Noldus J, Tannapfel A and Mirmohammadsadegh A: MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer. Int J Oncol 43: 307-314, 2013.
-
(2013)
Int J Oncol
, vol.43
, pp. 307-314
-
-
Verdoodt, B.1
Neid, M.2
Vogt, M.3
Kuhn, V.4
Liffers, S.T.5
Palisaar, R.J.6
Noldus, J.7
Tannapfel, A.8
Mirmohammadsadegh, A.9
-
10
-
-
84912564981
-
Double-negative feedback loop between ZEB2 and MIR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells
-
Ren D, Wang M, Guo W, Huang S, Wang Z, Zhao X, Du H, Song L and Peng X: Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells. Cell Tissue Res 358: 763-778, 2014.
-
(2014)
Cell Tissue Res
, vol.358
, pp. 763-778
-
-
Ren, D.1
Wang, M.2
Guo, W.3
Huang, S.4
Wang, Z.5
Zhao, X.6
Du, H.7
Song, L.8
Peng, X.9
-
11
-
-
84930274589
-
Stromal fibroblast-derived MIR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis
-
Josson S, Gururajan M, Sung SY, Hu P, Shao C, Zhau HE, Liu C, Lichterman J, Duan P, Li Q, et al: Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis. Oncogene 34: 2690-2699, 2015.
-
(2015)
Oncogene
, vol.34
, pp. 2690-2699
-
-
Josson, S.1
Gururajan, M.2
Sung, S.Y.3
Hu, P.4
Shao, C.5
Zhau, H.E.6
Liu, C.7
Lichterman, J.8
Duan, P.9
Li, Q.10
-
12
-
-
84934953080
-
MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1
-
Rajendiran S, Parwani AV, Hare RJ, Dasgupta S, Roby RK and Vishwanatha JK: MicroRNA-940 suppresses prostate cancer migration and invasion by regulating MIEN1. Mol Cancer 13: 250, 2014.
-
(2014)
Mol Cancer
, vol.13
, pp. 250
-
-
Rajendiran, S.1
Parwani, A.V.2
Hare, R.J.3
Dasgupta, S.4
Roby, R.K.5
Vishwanatha, J.K.6
-
13
-
-
84921728619
-
MIR-146a functions as a tumor suppressor in prostate cancer by targeting Rac1
-
Sun Q, Zhao X, Liu X, Wang Y, Huang J, Jiang B, Chen Q and Yu J: miR-146a functions as a tumor suppressor in prostate cancer by targeting Rac1. Prostate 74: 1613-1621, 2014.
-
(2014)
Prostate
, vol.74
, pp. 1613-1621
-
-
Sun, Q.1
Zhao, X.2
Liu, X.3
Wang, Y.4
Huang, J.5
Jiang, B.6
Chen, Q.7
Yu, J.8
-
14
-
-
84930198902
-
Reconstitution of the ERG gene expression network reveals new biomarkers and therapeutic targets in ERG positive prostate tumors
-
Dubovenko A, Serebryiskaya T, Nikolsky Y, Nikolskaya T, Perlina A, JeBailey L, Bureeva S, Katta S, Srivastava S, Dobi A, et al: Reconstitution of the ERG gene expression network reveals new biomarkers and therapeutic targets in ERG positive prostate tumors. J Cancer 6: 490-501, 2015.
-
(2015)
J Cancer
, vol.6
, pp. 490-501
-
-
Dubovenko, A.1
Serebryiskaya, T.2
Nikolsky, Y.3
Nikolskaya, T.4
Perlina, A.5
JeBailey, L.6
Bureeva, S.7
Katta, S.8
Srivastava, S.9
Dobi, A.10
-
15
-
-
84855262722
-
Growth of human prostate cancer cells is significantly suppressed in vitro with sodium butyrate through apoptosis
-
Qiu J, Gao Z and Shima H: Growth of human prostate cancer cells is significantly suppressed in vitro with sodium butyrate through apoptosis. Oncol Rep 27: 160-167, 2012.
-
(2012)
Oncol Rep
, vol.27
, pp. 160-167
-
-
Qiu, J.1
Gao, Z.2
Shima, H.3
-
16
-
-
0041829414
-
A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines
-
Shi C, Yu L, Yang F, Yan J and Zeng H: A novel organoselenium compound induces cell cycle arrest and apoptosis in prostate cancer cell lines. Biochem Biophys Res Commun 309: 578-583, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.309
, pp. 578-583
-
-
Shi, C.1
Yu, L.2
Yang, F.3
Yan, J.4
Zeng, H.5
-
17
-
-
84937760476
-
MIR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2
-
Li X, Gong X, Chen J, Zhang J, Sun J and Guo M: miR-340 inhibits glioblastoma cell proliferation by suppressing CDK6, cyclin-D1 and cyclin-D2. Biochem Biophys Res Commun 460: 670-677, 2015.
-
(2015)
Biochem Biophys Res Commun
, vol.460
, pp. 670-677
-
-
Li, X.1
Gong, X.2
Chen, J.3
Zhang, J.4
Sun, J.5
Guo, M.6
-
18
-
-
84934981317
-
MIR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer
-
Fernandez S, Risolino M, Mandia N, Talotta F, Soini Y, Incoronato M, Condorelli G, Banfi S and Verde P: miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer. Oncogene 34: 3240-3250, 2015.
-
(2015)
Oncogene
, vol.34
, pp. 3240-3250
-
-
Fernandez, S.1
Risolino, M.2
Mandia, N.3
Talotta, F.4
Soini, Y.5
Incoronato, M.6
Condorelli, G.7
Banfi, S.8
Verde, P.9
-
20
-
-
84872045689
-
Gastric juice MIR-129 as a potential biomarker for screening gastric cancer
-
Yu X, Luo L, Wu Y, Yu X, Liu Y, Yu X, Zhao X, Zhang X, Cui L, Ye G, et al: Gastric juice miR-129 as a potential biomarker for screening gastric cancer. Med Oncol 30: 365, 2013.
-
(2013)
Med Oncol
, vol.30
, pp. 365
-
-
Yu, X.1
Luo, L.2
Wu, Y.3
Yu, X.4
Liu, Y.5
Yu, X.6
Zhao, X.7
Zhang, X.8
Cui, L.9
Ye, G.10
-
21
-
-
84925367818
-
Low MIR-34a and MIR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma
-
Wang Y, Jia LS, Yuan W, Wu Z, Wang HB, Xu T, Sun JC, Cheng KF and Shi JG: Low miR-34a and miR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma. Am J Transl Res 7: 111-119, 2015.
-
(2015)
Am J Transl Res
, vol.7
, pp. 111-119
-
-
Wang, Y.1
Jia, L.S.2
Yuan, W.3
Wu, Z.4
Wang, H.B.5
Xu, T.6
Sun, J.C.7
Cheng, K.F.8
Shi, J.G.9
-
22
-
-
77950665077
-
Therapeutic silencing of MIR-10b inhibits metastasis in a mouse mammary tumor model
-
Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Teruya-Feldstein J, Bell GW and Weinberg RA: Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat Biotechnol 28: 341-347, 2010.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 341-347
-
-
Ma, L.1
Reinhardt, F.2
Pan, E.3
Soutschek, J.4
Bhat, B.5
Marcusson, E.G.6
Teruya-Feldstein, J.7
Bell, G.W.8
Weinberg, R.A.9
-
23
-
-
84869220331
-
MicroRNAs in prostate cancer: From biomarkers to molecularly-based therapeutics
-
Gordanpour A, Nam RK, Sugar L and Seth A: MicroRNAs in prostate cancer: From biomarkers to molecularly-based therapeutics. Prostate Cancer Prostatic Dis 15: 314-319, 2012.
-
(2012)
Prostate Cancer Prostatic Dis
, vol.15
, pp. 314-319
-
-
Gordanpour, A.1
Nam, R.K.2
Sugar, L.3
Seth, A.4
-
24
-
-
79959811503
-
Downregulation of MIR-205 and MIR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells
-
Bhatnagar N, Li X, Padi SK, Zhang Q, Tang MS and Guo B: Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells. Cell Death Dis 1: e105, 2010.
-
(2010)
Cell Death Dis
, vol.1
, pp. e105
-
-
Bhatnagar, N.1
Li, X.2
Padi, S.K.3
Zhang, Q.4
Tang, M.S.5
Guo, B.6
-
25
-
-
84899738420
-
Identification of MIR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer
-
Li X, Wan X, Chen H, Yang S, Liu Y, Mo W, Meng D, Du W, Huang Y, Wu H, et al: Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer. Clin Cancer Res 20: 2312-2325, 2014.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2312-2325
-
-
Li, X.1
Wan, X.2
Chen, H.3
Yang, S.4
Liu, Y.5
Mo, W.6
Meng, D.7
Du, W.8
Huang, Y.9
Wu, H.10
-
26
-
-
79959624589
-
MIR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met
-
Wu ZS, Wu Q, Wang CQ, Wang XN, Huang J, Zhao JJ, Mao SS, Zhang GH, Xu XC and Zhang N: miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met. Cancer 117: 2842-2852, 2011.
-
(2011)
Cancer
, vol.117
, pp. 2842-2852
-
-
Wu, Z.S.1
Wu, Q.2
Wang, C.Q.3
Wang, X.N.4
Huang, J.5
Zhao, J.J.6
Mao, S.S.7
Zhang, G.H.8
Xu, X.C.9
Zhang, N.10
-
27
-
-
84881555440
-
MicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1
-
Zhou X, Wei M and Wang W: MicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1. Biochem Biophys Res Commun 437: 653-658, 2013.
-
(2013)
Biochem Biophys Res Commun
, vol.437
, pp. 653-658
-
-
Zhou, X.1
Wei, M.2
Wang, W.3
-
28
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
Honda R, Tanaka H and Yasuda H: Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 420: 25-27, 1997.
-
(1997)
FEBS Lett
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
29
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna R, Wagner DS and Lozano G: Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378: 203-206, 1995.
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
De Oca Luna, M.R.1
Wagner, D.S.2
Lozano, G.3
-
30
-
-
0029913730
-
Mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
-
Chen J, Wu X, Lin J and Levine AJ: mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol 16: 2445-2452, 1996.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 2445-2452
-
-
Chen, J.1
Wu, X.2
Lin, J.3
Levine, A.J.4
-
31
-
-
14644403700
-
MDM2 and human malignancies: Expression, clinical pathology, prognostic markers, and implications for chemotherapy
-
Rayburn E, Zhang R, He J and Wang H: MDM2 and human malignancies: Expression, clinical pathology, prognostic markers, and implications for chemotherapy. Curr Cancer Drug Targets 5: 27-41, 2005.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 27-41
-
-
Rayburn, E.1
Zhang, R.2
He, J.3
Wang, H.4
-
32
-
-
84926618053
-
MIR-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction
-
Fortunato O, Boeri M, Moro M, Verri C, Mensah M, Conte D, Caleca L, Roz L, Pastorino U and Sozzi G: mir-660 is downregulated in lung cancer patients and its replacement inhibits lung tumorigenesis by targeting MDM2-p53 interaction. Cell Death Dis 5: e1564, 2014.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1564
-
-
Fortunato, O.1
Boeri, M.2
Moro, M.3
Verri, C.4
Mensah, M.5
Conte, D.6
Caleca, L.7
Roz, L.8
Pastorino, U.9
Sozzi, G.10
-
33
-
-
17144463251
-
Abnormal expression of MDM2 in prostate carcinoma
-
Leite KR, Franco MF, Srougi M, Nesrallah LJ, Nesrallah A, Bevilacqua RG, Darini E, Carvalho CM, Meirelles MI, Santana I, et al: Abnormal expression of MDM2 in prostate carcinoma. Mod Pathol 14: 428-436, 2001.
-
(2001)
Mod Pathol
, vol.14
, pp. 428-436
-
-
Leite, K.R.1
Franco, M.F.2
Srougi, M.3
Nesrallah, L.J.4
Nesrallah, A.5
Bevilacqua, R.G.6
Darini, E.7
Carvalho, C.M.8
Meirelles, M.I.9
Santana, I.10
-
34
-
-
0141482040
-
Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy
-
Zhang Z, Li M, Wang H, Agrawal S and Zhang R: Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy. Proc Natl Acad Sci USA 100: 11636-11641, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11636-11641
-
-
Zhang, Z.1
Li, M.2
Wang, H.3
Agrawal, S.4
Zhang, R.5
-
35
-
-
84875596803
-
The role of MIR-18b in MDM2-p53 pathway signaling and melanoma progression
-
Dar AA, Majid S, Rittsteuer C, de Semir D, Bezrookove V, Tong S, Nosrati M, Sagebiel R, Miller JR III and Kashani-Sabet M: The role of miR-18b in MDM2-p53 pathway signaling and melanoma progression. J Natl Cancer Inst 105: 433-442, 2013.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 433-442
-
-
Dar, A.A.1
Majid, S.2
Rittsteuer, C.3
De Semir, D.4
Bezrookove, V.5
Tong, S.6
Nosrati, M.7
Sagebiel, R.8
Miller, J.R.9
Kashani-Sabet, M.10
-
36
-
-
32444449180
-
Small molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
-
Tovar C, Rosinski J, Filipovic Z, Higgins B, Kolinsky K, Hilton H, Zhao X, Vu BT, Qing W, Packman K, et al: Small molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy. Proc Natl Acad Sci USA 103: 1888-1893, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1888-1893
-
-
Tovar, C.1
Rosinski, J.2
Filipovic, Z.3
Higgins, B.4
Kolinsky, K.5
Hilton, H.6
Zhao, X.7
Vu, B.T.8
Qing, W.9
Packman, K.10
-
37
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev LT, Vu BT, Graves B, Carvajal D, Podlaski F, Filipovic Z, Kong N, Kammlott U, Lukacs C, Klein C, et al: In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303: 844-848, 2004.
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
-
38
-
-
70949084205
-
Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction
-
Allen JG, Bourbeau MP, Wohlhieter GE, Bartberger MD, Michelsen K, Hungate R, Gadwood RC, Gaston RD, Evans B, Mann LW, et al: Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction. J Med Chem 52: 7044-7053, 2009.
-
(2009)
J Med Chem
, vol.52
, pp. 7044-7053
-
-
Allen, J.G.1
Bourbeau, M.P.2
Wohlhieter, G.E.3
Bartberger, M.D.4
Michelsen, K.5
Hungate, R.6
Gadwood, R.C.7
Gaston, R.D.8
Evans, B.9
Mann, L.W.10
|