Effectiveness of lycopene on experimental testicular torsion

Journal of Pediatric Surgery

Volumn 51, Issue 7, 2016, Pages 1187-1191

  Güzel, Mahmut ^a   Sönmez, Mehmet Fatih ^a   Baştuğ, Osman ^b   Aras, Necip Fazıl ^a   Öztürk, Ayşe Betül ^a   Küçükaydın, Mustafa ^a   Turan, Cüneyt ^a  

^a ERCIYES UNIVERSITY   (Turkey)

^b Training and Research Hospital ^*  (Turkey)

Author keywords

Antioxidant; Ischemia reperfusion; Lycopene; Testis; Torsion

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; LYCOPENE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; TESTOSTERONE; TUMOR NECROSIS FACTOR; ANTIOXIDANT; BIOLOGICAL MARKER; CAROTENOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOCHEMICAL ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DRUG EFFICACY; HISTOPATHOLOGY; JOHNSEN SCORE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REFERENCE VALUE; REPERFUSION INJURY; SCORING SYSTEM; SEMINIFEROUS TUBULE; SPERMATOGENESIS; TESTIS; TESTIS TISSUE; TESTIS TORSION; TESTOSTERONE BLOOD LEVEL; TUNEL ASSAY; ANIMAL; COMPLICATION; DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; RANDOMIZATION; TREATMENT OUTCOME; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BIOMARKERS; CAROTENOIDS; DRUG ADMINISTRATION SCHEDULE; INJECTIONS, INTRAPERITONEAL; MALE; RANDOM ALLOCATION; RATS; RATS, WISTAR; REPERFUSION INJURY; SPERMATIC CORD TORSION; TESTIS; TREATMENT OUTCOME;

EID: 84954285385     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2015.11.008     Document Type: Article

References (25)

1. Hutson, J.M., Undescended testis, torsion and varicocele. Coran, A.G., (eds.) Pediatric Surgery, 2012, Elsevier Saunders, Philadelphia, 1003–1020.
2. Karaguzel, E., Kadihasanoglu, M., Kutlu, O., Mechanisms of testicular torsion and potential protective agents. Nat Rev Urol 11 (2014), 391–399.
3. Bramley, P.M., Is lycopene beneficial to human health?. Phytochemistry 54 (2000), 233–236.
4. Rao, L.G., Guns, E., Rao, A.V., Lycopene: its role in human health and disease. Agro Food 7–8 (2003), 25–30.
5. Kanter, M., Protective effects of melatonin on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats. Exp Mol Pathol 89:3 (2010), 314–320.
6. Johnsen, S.G., Testicular biopsy score count—a method for registration of spermatogenesis in human testes: normal values and results in 335 hypogonadal males. Hormones 1:1 (1970), 2–25.
7. Bayatli, F., Akkus, D., Kilic, E., et al. The protective effects of grape seed extract on MDA, AOPP, apoptosis and eNOS expression in testicular torsion: an experimental study. World J Urol 31 (2013), 615–622.
8. Bansal, P., Gupta, S.K., Ojha, S.K., et al. Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury. Mol Cell Biochem 289:1-2 (2006), 1–9.
9. Wei, Y., Shen, X., Shen, H., et al. Effects of lycopene on cerebral ischemia-reperfusion injury in rats. Wei Sheng Yan Jiu 39 (2010), 201–204.
10. Bignotto, L., Rocha, J., Sepodes, B., et al. Anti-inflammatory effect of lycopene on carrageenan-induced paw oedema and hepatic ischaemia-reperfusion in the rat. Br J Nutr 102 (2009), 126–133.
11. Li, Y., Xue, F., Xu, S.Z., et al. Lycopene protects bone marrow mesenchymal stem cells against ischemia-induced apoptosis in vitro. Eur Rev Med Pharmaco 18 (2014), 1625–1631.
12. Özkan, E., Akyüz, C., Dulundu, E., et al. Protective effects of lycopene on cerulein induced experimental acute pancreatitis in rats. J Surg Res 176 (2012), 232–238.
13. Kaya, C., Karabulut, R., Turkyilmaz, Z., et al. Lycopene has reduced renal damage histopathologically and biochemically in experimental renal ischemia-reperfusion injury. Ren Fail 10 (2015), 1–6.
14. Breinholta, V., Lauridsena, S.T., Daneshvara, B., et al. Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat. Cancer Lett 154 (2000), 201–210.
15. Cadenas, E., Packer, L., Handbook of antioxidants. 2nd ed., 2002, Marcel Dekker Inc, New York.
16. Hekimoglu, A., Kurcer, Z., Aral, F., et al. Lycopene, an antioxidant carotenoid, attenuates testicular injury caused by ischemia/reperfusion in rats. Tohoku J Exp Med 218:2 (2009), 141–147.
17. Bozlu, M., Acar, D., Cayan, S., et al. Protective effect of trapidil on long-term histologic damage in a rat model of testicular ischemia-reperfusion injury. World J Urol 27 (2009), 117–122.
18. Taşkara, E., Gör, A., Kutlu, Ö., et al. Does propofol prevent testicular ischemia–reperfusion injury due to torsion in the long term?. Pediatr Surg Int 27 (2011), 1003–1007.
19. Turkmen, S., Mentese, A., Karaguzel, E., et al. A comparison of the effects of N-acetylcysteine and ethyl pyruvate on experimental testicular ischemia-reperfusion injury. Fertil Steril 98:3 (2012), 626–631.
20. Wei, S.M., Yan, Z.Z., Zhou, J., Curcumin attenuates ischemia-reperfusion injury in rat testis. Fertil Steril 91:1 (2009), 271–277.
21. Erol, B., Tokgoz, H., Hanci, V., et al. Vardenafil reduces testicular damage following ischemia/reperfusion injury in rats. Kaohsiung J Med Sci 25:7 (2009), 374–380.
22. Kanter, M., Protective effects of Ginkgo biloba (EGb 761) on testicular torsion/detorsion-induced ischemia-reperfusion injury in rats. Exp Mol Pathol 9:3 (2011), 708–713.
23. Ho, E., Karimi Galougahi, K., Liu, C.C., et al. Biological markers of oxidative stress: applications to cardiovascular research and practice. Redox Biol 1 (2013), 483–491.
24. Starkie, R., Ostrowski, S.R., Jauffred, S., et al. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. FASEB J 17:8 (2003), 884–886.
25. Mooradian, A.D., Morley, J.E., Korenman, S.G., Biological actions of androgens. Endocr Rev 8:1 (1987), 1–28.