Is lycopene beneficial to human health?

Phytochemistry

Volumn 54, Issue 3, 2000, Pages 233-236

  Bramley, Peter M ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cancer; Carotenoids; Chronic diseases; Coronary heart disease; Diet; Lycopene; Tomato

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; CAROTENE; CAROTENOID; LYCOPENE; TRACE ELEMENT;

ARTICLE; BIOSYNTHESIS; CANCER PREVENTION; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHRONIC DISEASE; DIET; DISEASE ASSOCIATION; HEALTH; HUMAN; HUMAN TISSUE; ISCHEMIC HEART DISEASE; NEOPLASM; NUTRIENT; RISK ASSESSMENT; TISSUE DISTRIBUTION; TISSUE LEVEL; TOMATO;

ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CAROTENOIDS; DIET; HUMANS; MICRONUTRIENTS; NEOPLASMS; TISSUE DISTRIBUTION;

LYCOPERSICON ESCULENTUM;

EID: 0034625765     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9422(00)00103-5     Document Type: Article

References (24)

1. Blakely S.R., Brown E.D., Babu U., Grundel E., Mitchell G.V. Bioavailability of carotenoids in tomato paste and dried spinach and their interactions with canthaxanthin. FASEB J. 8:1994;192.
2. Bohm V., Bitsch R. Intestinal absorption of lycopene from different matrices and interactions to other carotenoids, the lipid status and the antioxidant capacity of human plasma. Eur. J. Nutr. 38:1999;118-125.
3. Boileau A.C., Merchen N.R., Wasson K., Atkinson C.A., Erdman J.W. Jr. Cis-lycopene is more bioavailable than trans-lycopene in vitro and in vivo in lymph-cannulated ferrets. J. Nutr. 129:1999;1176-1181.
4. Bramley P.M. The regulation and genetic manipulation of carotenoid biosynthesis in tomato fruit. Pure Appl. Chem. 69:1997;2159-2162.
5. Clinton S.K., Emenhiser C., Schwartz S.J. Cis-trans lycopene isomers, carotenoids and retinol in the human prostate. Cancer Epidemiol. Biomarkers Prev. 5:1996;823-833.
6. Dorgan J.F., Sowell A., Swanson C.A., Potischman N., Miller R., Schussler N., Stephenson H.E. Jr. Relationship of serum carotenoids, retinol, α-tocopherol and selenium with breast cancer risk: results from a prospective study in Columbia, Missouri. Cancer Causes Control. 9:1998;89-97.
7. Franceschi S., Bidoli E., LaVeccia C., Talamini R., D'Avanzo B., Negri E. Tomatoes and risk of digestive tract cancers. Int. J. Cancer. 59:1994;181-184.
8. Giovannucci E., Ascherio A., Rimm E.B., Stampfer M.J., Colditz G.A., Willett W.C. Intake of carotenoids and retinol in relation to risk of prostate cancer. J. Natl. Cancer Inst. 87:1995;1767-1776.
9. Harker M., Hirschberg J. Molecular biology of carotenoid biosynthesis in photosynthetic organisms. Methods Enzymol. 297:1998;244-263.
10. Helzlsouer K.J., Comstock G.W., Morris J.S. Selenium, lycopene, α-tocopherol, β-carotene, retinol and subsequent bladder cancer. Cancer Res. 49:1989;6144-6148.
11. Holloway D.E., Yang M., Paganga G., Rice-Evans C.A., Bramley P.M. Isomerization of dietary lycopene during assimilation and transport in plasma. Free Rad. Res. 32:2000;93-102.
12. Khachik F., Beecher G.R., Goli M.B., Lusby W.R., Smith J.C. Separation and identification of carotenoids and their oxidative products in extracts of human plasma. Anal. Chem. 64:1992;2111-2122.
13. Kohlmeier L., Kark J.D., Gomez-Garcia E., Martin B.C., Steck S.E., Kardinaal A.F.M., Ringstad J., Thamm M., Masaev V., Riemersma R., Martin-Moreno J.M., Huttunen J.K., Kok F.J. Lycopene and myocardial infarction risk in the EURAMIC study. Am. J. Epidemiol. 140:1997;618-626.
14. Kristenson M., Zieden B., Kucinskiene Z., Elinder L.S., Bergdahl B., Abaraqvicius A., Razinkoviene L., Calkauskas H., Olsson A. Antioxidant state and mortality form coronary heart disease in Lithuania and Swedish men: concomitant cross sectional study of men aged 50. Brit. Med. J. 314:1997;629-633.
15. Rao A.V., Agarwal S. Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: a review. Nutr. Res. 19:1999;305-323.
16. Ribago-Mercado J.D., Garmyn M., Gilchrest B.A., Russell R.M. Skin lycopene is destroyed preferentially over β-carotene during UV irradiation in humans. J. Nutr. 125:1995;1854-1859.
17. Rice-Evans C.A., Sampson J., Bramley P.M., Holloway D.E. Why do we expect carotenoids to be antioxidants in vivo? Free Rad. Res. 26:1997;381-398.
18. Schmitz H.H., Poor C.L., Wellman R.B., Erdman Jr. J.W. Concentrations of selected carotenoids and vitamin A in human liver, kidney, and lung tissue. J. Nutr. 121:1991;1613-1621.
19. Scott K.J., Hart D.J. Development and evaluation of an HPLC method for the analysis of carotenoids in foods and the measurement of carotenoid content of vegetables and fruits commonly consumed in the UK. Food Chem. 54:1995;101-111.
20. Sengupta A., Das S. The anti-carcinogenic role of lycopene, abundantly present in tomato. Eur. J. Cancer Prevention. 8:1999;325-330.
21. Shi J., Le Mageur M. Lycopene in tomatoes: chemical and physical properties affected by food processing. Crit. Rev. Food Sci. Nutr. 40:2000;1-42.
22. Stahl W., Schwarz W., Sundquist A.R., Sies H. Cis-trans isomers of lycopene and β-carotene in human serum and tissues. Archiv. Biochem. Biophys. 294:1992;173-177.
23. Tonucci L.H., Holden J.M., Beecher G.R., Khachik F., Davis C.S., Mulokozzi G. Carotenoid contents of thermally processed tomato-based food products. J. Agric. Food Chem. 43:1995;579-586.
24. Zhang L-X., Conney R.V., Bertram J.S. Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/1077/2 cells: relationship to their cancer chemopreventative action. Carcinogenesis. 12:1991;2109-2114.