-
1
-
-
84858800620
-
The immune contexture in human tumours: Impact on clinical outcome
-
Fridman WH, Pagès F, Sautès-Fridman C, et al. The immune contexture in human tumours: impact on clinical outcome. Nat Rev Cancer 2012;12:298-306.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 298-306
-
-
Fridman, W.H.1
Pagès, F.2
Sautès-Fridman, C.3
-
2
-
-
77951217044
-
High frequency of tumor-infiltrating FOXP3+ regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients
-
Frey DM, Droeser RA, Viehl CT, et al. High frequency of tumor-infiltrating FOXP3+ regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients. Int J Cancer 2010;126:2635-43.
-
(2010)
Int J Cancer
, vol.126
, pp. 2635-2643
-
-
Frey, D.M.1
Droeser, R.A.2
Viehl, C.T.3
-
3
-
-
58249089749
-
Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
-
Salama P, Phillips M, Grieu F, et al. Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer. J Clin Oncol 2009;27:186-92.
-
(2009)
J Clin Oncol
, vol.27
, pp. 186-192
-
-
Salama, P.1
Phillips, M.2
Grieu, F.3
-
4
-
-
84878450875
-
High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor
-
Droeser RA, Hirt C, Eppenberger-Castori S, et al. High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favorable prognostic factor. PLoS ONE 2013;8:e64814.
-
(2013)
PLoS ONE
, vol.8
, pp. e64814
-
-
Droeser, R.A.1
Hirt, C.2
Eppenberger-Castori, S.3
-
5
-
-
84890281390
-
Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis
-
Hirt C, Eppenberger-Castori S, Sconocchia G, et al. Colorectal carcinoma infiltration by myeloperoxidase-expressing neutrophil granulocytes is associated with favorable prognosis. Oncoimmunology 2013;2:e25990.
-
(2013)
Oncoimmunology
, vol.2
, pp. e25990
-
-
Hirt, C.1
Eppenberger-Castori, S.2
Sconocchia, G.3
-
6
-
-
79952282602
-
Tumor infiltration by FcgammaRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma
-
Sconocchia G, Zlobec I, Lugli A, et al. Tumor infiltration by FcgammaRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma. Int J Cancer 2011;128:2663-72.
-
(2011)
Int J Cancer
, vol.128
, pp. 2663-2672
-
-
Sconocchia, G.1
Zlobec, I.2
Lugli, A.3
-
7
-
-
79953681584
-
IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma
-
Liu J, Duan Y, Cheng X, et al. IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem Biophys Res Commun 2011;407:348-54.
-
(2011)
Biochem Biophys Res Commun
, vol.407
, pp. 348-354
-
-
Liu, J.1
Duan, Y.2
Cheng, X.3
-
8
-
-
79951815749
-
Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer
-
Tosolini M, Kirilovsky A, Mlecnik B, et al. Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. Cancer Res 2011;71:1263-71.
-
(2011)
Cancer Res
, vol.71
, pp. 1263-1271
-
-
Tosolini, M.1
Kirilovsky, A.2
Mlecnik, B.3
-
9
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector T cell lineages
-
Weaver CT, Hatton RD, Mangan PR, et al. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007;25:821-52.
-
(2007)
Annu Rev Immunol
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
-
11
-
-
65549088243
-
IL-17-producing human peripheral regulatory T cells retain suppressive function
-
Beriou G, Costantino CM, Ashley CW, et al. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 2009;113:4240-9.
-
(2009)
Blood
, vol.113
, pp. 4240-4249
-
-
Beriou, G.1
Costantino, C.M.2
Ashley, C.W.3
-
12
-
-
63849183918
-
Identification of IL-17-producing FOXP3+ regulatory T cells in humans
-
Voo KS, Wang YH, Santori FR, et al. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proc Natl Acad Sci U S A 2009;106:4793-8.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
-
13
-
-
55149094300
-
Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
-
Koenen HJ, Smeets RL, Vink PM, et al. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008;112:2340-52.
-
(2008)
Blood
, vol.112
, pp. 2340-2352
-
-
Koenen, H.J.1
Smeets, R.L.2
Vink, P.M.3
-
14
-
-
77954143695
-
Innate IL-17-producing cells: The sentinels of the immune system
-
Cua DJ, Tato CM. Innate IL-17-producing cells: the sentinels of the immune system. Nat Rev Immunol 2010;10:479-89.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
15
-
-
84872977452
-
Innate lymphoid cells - A proposal for uniform nomenclature
-
Spits H, Artis D, Colonna M, et al. Innate lymphoid cells - a proposal for uniform nomenclature. Nat Rev Immunol 2013;13:145-9.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 145-149
-
-
Spits, H.1
Artis, D.2
Colonna, M.3
-
16
-
-
33846966636
-
A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med 2007;13:139-45.
-
(2007)
Nat Med
, vol.13
, pp. 139-145
-
-
Steinman, L.1
-
17
-
-
77950420796
-
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis
-
Chae WJ, Gibson TF, Zelterman D, et al. Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci USA 2010;107:5540-4.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5540-5544
-
-
Chae, W.J.1
Gibson, T.F.2
Zelterman, D.3
-
18
-
-
84883745262
-
An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy
-
Chung AS, Wu X, Zhuang G, et al. An interleukin-17-mediated paracrine network promotes tumor resistance to anti-angiogenic therapy. Nat Med 2013;19:1114-23.
-
(2013)
Nat Med
, vol.19
, pp. 1114-1123
-
-
Chung, A.S.1
Wu, X.2
Zhuang, G.3
-
19
-
-
84868613705
-
Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth
-
Grivennikov SI, Wang K, Mucida D, et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012;491:254-8.
-
(2012)
Nature
, vol.491
, pp. 254-258
-
-
Grivennikov, S.I.1
Wang, K.2
Mucida, D.3
-
20
-
-
0037849915
-
Interleukin-17 promotes angiogenesis and tumor growth
-
Numasaki M, Fukushi J, Ono M, et al. Interleukin-17 promotes angiogenesis and tumor growth. Blood 2003;101:2620-7.
-
(2003)
Blood
, vol.101
, pp. 2620-2627
-
-
Numasaki, M.1
Fukushi, J.2
Ono, M.3
-
21
-
-
84918535539
-
Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis
-
Wang K, Kim MK, Di Caro G, et al. Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis. Immunity 2014;41:1052-63.
-
(2014)
Immunity
, vol.41
, pp. 1052-1063
-
-
Wang, K.1
Kim, M.K.2
Di Caro, G.3
-
22
-
-
69949120571
-
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
-
Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med 2009;15:1016-22.
-
(2009)
Nat Med
, vol.15
, pp. 1016-1022
-
-
Wu, S.1
Rhee, K.J.2
Albesiano, E.3
-
23
-
-
84865720500
-
Anti-IL-17 mAbs herald new options in psoriasis
-
Garber K. Anti-IL-17 mAbs herald new options in psoriasis. Nat Biotechnol 2012;30:475-7.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 475-477
-
-
Garber, K.1
-
25
-
-
84887076617
-
IL-17 antibodies gain momentum
-
Tse MT. IL-17 antibodies gain momentum. Nat Rev Drug Discov 2013;12:815-16.
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 815-816
-
-
Tse, M.T.1
-
26
-
-
84876297224
-
Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases
-
Wang K, Grivennikov SI, Karin M. Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases. Ann Rheum Dis 2013;72(Suppl 2):ii100-3.
-
(2013)
Ann Rheum Dis
, vol.72
, pp. ii100-ii103
-
-
Wang, K.1
Grivennikov, S.I.2
Karin, M.3
-
27
-
-
84856708250
-
Are we ready to start studies of Th17 cell manipulation as a therapy for cancer?
-
Middleton GW, Annels NE, Pandha HS. Are we ready to start studies of Th17 cell manipulation as a therapy for cancer? Cancer Immunol Immunother 2012;61:1-7.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1-7
-
-
Middleton, G.W.1
Annels, N.E.2
Pandha, H.S.3
-
28
-
-
78650744474
-
TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer
-
Zlobec I, Karamitopoulou E, Terracciano L, et al. TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer. PLoS One 2010;5:e14282.
-
(2010)
PLoS One
, vol.5
, pp. e14282
-
-
Zlobec, I.1
Karamitopoulou, E.2
Terracciano, L.3
-
29
-
-
34848842992
-
Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer
-
Zlobec I, Steele R, Terracciano L, et al. Selecting immunohistochemical cut-off scores for novel biomarkers of progression and survival in colorectal cancer. J Clin Pathol 2007;60:1112-16.
-
(2007)
J Clin Pathol
, vol.60
, pp. 1112-1116
-
-
Zlobec, I.1
Steele, R.2
Terracciano, L.3
-
30
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez EV, Rivino L, Geginat J, et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol 2007;8:639-46.
-
(2007)
Nat Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
-
31
-
-
84930804769
-
Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo"
-
Hirt C, Papadimitropoulos A, Muraro MG, et al. Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed "in vivo". Biomaterials 2015;62:138-46.
-
(2015)
Biomaterials
, vol.62
, pp. 138-146
-
-
Hirt, C.1
Papadimitropoulos, A.2
Muraro, M.G.3
-
32
-
-
70349968210
-
CD8+ lymphocytes/ tumour-budding index: An independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer
-
Lugli A, Karamitopoulou E, Panayiotides I, et al. CD8+ lymphocytes/ tumour-budding index: an independent prognostic factor representing a 'pro-/anti-tumour' approach to tumour host interaction in colorectal cancer. Br J Cancer 2009;101:1382-92.
-
(2009)
Br J Cancer
, vol.101
, pp. 1382-1392
-
-
Lugli, A.1
Karamitopoulou, E.2
Panayiotides, I.3
-
33
-
-
84859491118
-
Combination of IL-17 and TNFalpha induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells
-
Hot A, Lenief V, Miossec P. Combination of IL-17 and TNFalpha induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells. Ann Rheum Dis 2012;71:768-76.
-
(2012)
Ann Rheum Dis
, vol.71
, pp. 768-776
-
-
Hot, A.1
Lenief, V.2
Miossec, P.3
-
34
-
-
75949102667
-
Interleukin-17 and its target genes: Mechanisms of interleukin-17 function in disease
-
Onishi RM, Gaffen SL. Interleukin-17 and its target genes: mechanisms of interleukin-17 function in disease. Immunology 2010;129:311-21.
-
(2010)
Immunology
, vol.129
, pp. 311-321
-
-
Onishi, R.M.1
Gaffen, S.L.2
-
35
-
-
23944469303
-
Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma
-
Musha H, Ohtani H, Mizoi T, et al. Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma. Int J Cancer 2005;116:949-56.
-
(2005)
Int J Cancer
, vol.116
, pp. 949-956
-
-
Musha, H.1
Ohtani, H.2
Mizoi, T.3
-
36
-
-
25444435416
-
Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts
-
Braccini A, Wendt D, Jaquiery C, et al. Three-dimensional perfusion culture of human bone marrow cells and generation of osteoinductive grafts. Stem Cells 2005;23:1066-72.
-
(2005)
Stem Cells
, vol.23
, pp. 1066-1072
-
-
Braccini, A.1
Wendt, D.2
Jaquiery, C.3
-
37
-
-
77950914422
-
In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction
-
Blatner NR, Bonertz A, Beckhove P, et al. In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction. Proc Natl Acad Sci USA 2010;107:6430-5.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6430-6435
-
-
Blatner, N.R.1
Bonertz, A.2
Beckhove, P.3
-
38
-
-
79955040909
-
IL-17+ Regulatory T Cells in the microenvironments of chronic inflammation and cancer
-
Kryczek I, Wu K, Zhao E, et al. IL-17+ Regulatory T Cells in the microenvironments of chronic inflammation and cancer. J Immunol 2011;186:4388-95.
-
(2011)
J Immunol
, vol.186
, pp. 4388-4395
-
-
Kryczek, I.1
Wu, K.2
Zhao, E.3
-
39
-
-
77949329050
-
Tumor microenvironments direct the recruitment and expansion of human Th17 cells
-
Su X, Ye J, Hsueh EC, et al. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 2010;184:1630-41.
-
(2010)
J Immunol
, vol.184
, pp. 1630-1641
-
-
Su, X.1
Ye, J.2
Hsueh, E.C.3
-
40
-
-
79251557498
-
Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer
-
Yang S, Wang B, Guan C, et al. Foxp3+IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer. J Leukoc Biol 2011;89:85-91.
-
(2011)
J Leukoc Biol
, vol.89
, pp. 85-91
-
-
Yang, S.1
Wang, B.2
Guan, C.3
-
41
-
-
84900482064
-
GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer
-
Wu P, Wu D, Ni C, et al. GammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 2014;40:785-800.
-
(2014)
Immunity
, vol.40
, pp. 785-800
-
-
Wu, P.1
Wu, D.2
Ni, C.3
-
42
-
-
84862141704
-
Human gut microbiome viewed across age and geography
-
Yatsunenko T, Rey FE, Manary MJ, et al. Human gut microbiome viewed across age and geography. Nature 2012;486:222-7.
-
(2012)
Nature
, vol.486
, pp. 222-227
-
-
Yatsunenko, T.1
Rey, F.E.2
Manary, M.J.3
-
43
-
-
84861980130
-
Interactions between the microbiota and the immune system
-
Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science 2012;336:1268-73.
-
(2012)
Science
, vol.336
, pp. 1268-1273
-
-
Hooper, L.V.1
Littman, D.R.2
Macpherson, A.J.3
-
44
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
Ivanov II, Atarashi K, Manel N, et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009;139:485-98.
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
-
45
-
-
80054121352
-
Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity
-
Ankathatti MM, Deng Y, Mulligan SJ, et al. Th17 and Th17-stimulated CD8(+) T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity. Cancer Immunol Immunother 2011;60:1473-84.
-
(2011)
Cancer Immunol Immunother
, vol.60
, pp. 1473-1484
-
-
Ankathatti, M.M.1
Deng, Y.2
Mulligan, S.J.3
-
46
-
-
70449530422
-
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
-
Martin-Orozco N, Muranski P, Chung Y, et al. T helper 17 cells promote cytotoxic T cell activation in tumor immunity. Immunity 2009;31:787-98.
-
(2009)
Immunity
, vol.31
, pp. 787-798
-
-
Martin-Orozco, N.1
Muranski, P.2
Chung, Y.3
-
47
-
-
70449715722
-
Protumor vs antitumor functions of IL-17
-
Murugaiyan G, Saha B. Protumor vs antitumor functions of IL-17. J Immunol 2009;183:4169-75.
-
(2009)
J Immunol
, vol.183
, pp. 4169-4175
-
-
Murugaiyan, G.1
Saha, B.2
-
48
-
-
84954566376
-
The correlations between IL-17 vs. Th17 cells and cancer patient survival: A systematic review
-
Punt S, Langenhoff JM, Putter H, et al. The correlations between IL-17 vs. Th17 cells and cancer patient survival: a systematic review. Oncoimmunology 2015;4:e984547.
-
(2015)
Oncoimmunology
, vol.4
, pp. e984547
-
-
Punt, S.1
Langenhoff, J.M.2
Putter, H.3
-
49
-
-
79955758706
-
Th17 cells in cancer: Help or hindrance?
-
Wilke CM, Kryczek I, Wei S, et al. Th17 cells in cancer: help or hindrance? Carcinogenesis 2011;32:643-9.
-
(2011)
Carcinogenesis
, vol.32
, pp. 643-649
-
-
Wilke, C.M.1
Kryczek, I.2
Wei, S.3
-
50
-
-
77950196277
-
T(H)17 cells in tumour immunity and immunotherapy
-
Zou W, Restifo NP. T(H)17 cells in tumour immunity and immunotherapy. Nat Rev Immunol 2010;10:248-56.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 248-256
-
-
Zou, W.1
Restifo, N.P.2
|