Triptolide reverses the Taxol resistance of lung adenocarcinoma by inhibiting the NF-κB signaling pathway and the expression of NF-κB-regulated drug-resistant genes

Molecular Medicine Reports

Volumn 13, Issue 1, 2016, Pages 153-159

  Jiang, Ning ^a   Dong, Xiao Peng ^a   Zhang, Suo Lin ^a   You, Qing Yong ^a   Jiang, Xing Tao ^a   Zhao, Xiao Gang ^a  

^a THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

Author keywords

Lung adenocarcinoma; NF B; Resistance reversal; Taxol resistant; Triptolide

Indexed keywords

CASPASE 8; CYCLOOXYGENASE 2; FLICE LIKE INHIBITORY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; PROTEIN BCL 2; PROTEIN BCL XL; TRIPTOLIDE; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE; TUMOR PROTEIN;

A549 CELL LINE; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL CYCLE REGULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IC50; IMMUNOFLUORESCENCE; LUNG ADENOCARCINOMA; PHARMACOGENETICS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TREATMENT DURATION; TRIPTERYGIUM WILFORDII; WESTERN BLOTTING; ADENOCARCINOMA; CELL CYCLE CHECKPOINT; CELL CYCLE S PHASE; DOSE RESPONSE; DRUG EFFECTS; DRUG RESISTANCE; GENETICS; LUNG TUMOR; METABOLISM; MULTIDRUG RESISTANCE; PATHOLOGY; TIME FACTOR; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EPOXY COMPOUNDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; NEOPLASM PROTEINS; NF-KAPPA B; PACLITAXEL; PHENANTHRENES; S PHASE; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84954239386     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4493     Document Type: Article

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