Galectin-1 suppresses methamphetamine induced neuroinflammation in human brain microvascular endothelial cells: Neuroprotective role in maintaining blood brain barrier integrity

Brain Research

Volumn 1624, Issue , 2015, Pages 175-187

  Parikh, Neil U ^a   Aalinkeel, R ^a   Reynolds, J L ^a   Nair, B B ^a   Sykes, D E ^a   Mammen, M J ^a   Schwartz, S A ^a   Mahajan, S D ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Blood brain barrier; Galectin 1; Human brain microvascular endothelial cells; Methamphetamine; Oxidative stress; Proinflammatory cytokines; Tight junctions; Transendothelial electrical resistance

Indexed keywords

CLAUDIN 3; ECALECTIN; GALECTIN 1; GALECTIN 3; INTERCELLULAR ADHESION MOLECULE 1; METHAMPHETAMINE; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; CENTRAL STIMULANT AGENT; CLAUDIN 5; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYTOKINE; MESSENGER RNA; NEUROPROTECTIVE AGENT; TJP1 PROTEIN, HUMAN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CAPILLARY ENDOTHELIAL CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMBRANE PERMEABILITY; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; BRAIN; CAPILLARY PERMEABILITY; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; DRUG INTERACTION; ENDOTHELIUM CELL; GENETICS; METABOLISM;

BRAIN; CAPILLARY PERMEABILITY; CELL SURVIVAL; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM STIMULANTS; CLAUDIN-5; CREB-BINDING PROTEIN; CYTOKINES; DRUG INTERACTIONS; ENDOTHELIAL CELLS; GALECTIN 1; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; METHAMPHETAMINE; NEUROPROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84954210792     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.07.033     Document Type: Article

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