Galectins, galactoside-binding mammalian lectins: Clinical application of multi-functional proteins

Acta Medica Okayama

Volumn 55, Issue 1, 2001, Pages 11-17

  Wada, Jim ^a   Makino, Hirofumi ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

galactoside binding lectins; Apoptosis; Autoimmune diseases; Cell adhesion and proliferation; Diabetic vascular complications; Galectins; Oncogenesis

Indexed keywords

GALECTIN; HEMAGGLUTININ;

AUTOIMMUNE DISEASE; BINDING SITE; CANCER INVASION; CELL COMMUNICATION; CELL DIVISION; CHEMISTRY; GENE EXPRESSION REGULATION; HUMAN; INFLAMMATION; PHYSIOLOGY; REVIEW;

AUTOIMMUNE DISEASES; BINDING SITES; CELL COMMUNICATION; CELL DIVISION; GALECTINS; GENE EXPRESSION REGULATION; HEMAGGLUTININS; HUMANS; INFLAMMATION; NEOPLASM INVASIVENESS;

EID: 0035258771     PISSN: 0386300X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (56)

1. Barondes SH, Castronovo V, Cooper DN, Cummings RD, Dickamer K, Feizi T, Gitt MA, Hirabayashi J, Hughes C, Kasai K, Leffler H, Liu F-T, Lotan R, Mercurio AM, Monsigny M, Pillai S, Poirer F, Raz A, Rigby PWJ, Rini JM and Wang JL: Galectins: A family of animal β-galactoside-binding lectins. Cell (1994) 76, 597-598.
2. Cooper DN and Barondes SH: God must love galectins; he made so many of them. Glycobiology (1999) 9, 979-984.
3. Perillo NL, Marcus ME and Baum LG: Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol Med (1998) 76, 402-412.
4. Varki A: Selectin ligands. Proc Natl Acad Sci USA (1994) 91, 7390-7397.
5. Gitt MA, Wiser MF, Leffler H, Herrmann J, Xia YR, Massa SM, Cooper DN, Lusis AJ and Barondes SH: Sequence and mapping of galectin-5, a β-galactoside-binding lectin, found in rat erythrocytes. J Biol Chem (1995) 270, 5032-5038.
6. Gitt MA, Colnot C, Poirier F, Nani KJ, Barondes SH and Leffler H: Galectin-4 and galectin-6 are two closely related lectins expressed in mouse gastrointestinal tract. J Biol Chem (1998) 273, 2954-2960.
7. Madsen P, Rasmussen HH, Flint T, Gromov P, Kruse TA, Honore B, Vorum H and Celis JE: Cloning, expression, and chromosome mapping of human galectin-7. J Biol Chem (1995) 270, 5823-5829.
8. Magnaldo T, Bernerd F and Darmon M: Galectin-7: A human 14-kDa S-lectin, specifically expressed in keratinocytes and sensitive to retinoic acid. Dev Biol (1995) 168, 259-271.
9. Hadari YR, Paz K, Dekel R, Mestrovic T, Accili D and Zick Y: Galectin-8. A new rat lectin, related to galectin-4. J Biol Chem (1995) 270, 3447-3453.
10. Wada J and Kanwar YS: Identification and characterization of galectin-9, a novel β-galactoside-binding mammalian lectin. J Biol Chem (1997) 272, 6078-6086.
11. Tureci O, Schmitt H, Fadle N, Pfreundschuh M and Sahin U: Molecular definition of a novel human galectin which is immunogenic in patients with Hodgkin's disease. J Biol Chem (1997) 272, 6416-6422.
12. Leonidas DD, Elbert BL, Zhou Z, Leffler H, Ackerman SJ and Acharya KR: Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure (1995) 3, 1379-1393.
13. Dunphy JL, Balic A, Barcham GJ, Horvath AJ, Nash AD and Meeusen EN: Isolation and characterization of a novel inducible mammalian galectin. J Biol Chem (2000) 275, 32106-32113.
14. Hughes RC: Secretion of the galectin family of mammalian carbohydrate-binding proteins. Biochim Biophys Acta (1999) 1473, 172-185.
15. Wada J, Ota K, Kumar A, Wallner El and Kanwar YS: Developmental regulation, expression, and apoptotic potential of galectin-9, a β-galactoside binding lectin. J Clin Invest (1997) 99, 2452-2461.
16. Matsumoto R, Matsumoto H, Seki M, Hata M, Asano Y, Kanegasaki S, Stevens RL and Hirashima M: Human ecalectin, a variant of human galectin-9, is a novel eosinophil chemoattractant produced by T lymphocytes. J Biol Chem (1998) 273, 16976-16984.
17. Poirier F, Timmons PM, Chan C-T, Guenet J-L and Rigby PW: Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre-and post-implantation development. Development (1992) 115, 143-155.
18. Gillenwater A, Xu XC, Estrov Y, Sacks PG, Lotan D and Lotan R: Modulation of galectin-1 content in human head and neck squamous carcinoma cells by sodium butyrate. Int J Cancer (1998) 75, 217-224.
19. Hsu DK, Hammes SR, Kuwabara I, Greene WC and Liu F-T: Human T lymphotropic virus-1 infection of human T lymphocytes induces expression of the β-galactoside-binding lectin, galectin-3. Am J pathol (1996) 148, 1661-1670.
20. Gaudin JC, Arar C, Monsigny M and Legrand A: Modulation of the expression of the rabbit galectin-3 gene by p53 and c-Ha-ras proteins and PMA. Glycobiology (1997) 7, 1089-1098.
21. Sato S and Hughes RC: Regulation of secretion and surface expression of Mac-2, a galactoside-binding protein of macrophages. J Biol Chem (1994) 269, 4424-4430.
22. Rabinovich GA: Galectins: An evolutionary conserved family of animal lectins with multifunctional properties; A trip from the gene to clinical therapy. Cell Death Differ (1999) 6, 711-721.
23. Zhou Q and Cummings RD: L-14 lectin recognition of laminin and its promotion of in vitro cell adhesion. Arch Biochem Biophys (1993) 300, 6-17.
24. Ozeki Y, Matsui T, Yamamoto Y, Funahashi M, Hamako J and Titani K: Tissue fibronectin is an endogenous ligand for galectin-1. Glycobiology (1995) 5, 255-261.
25. Do K-Y, Smith DF and Cummings RD: LAMP-I in CHO cells is a primary carrier of poly-N-acetyllactosamine chains and is bound preferentially by a mammalian S-type lectin. Biochem Biophys Res Commun (1990) 173, 1123-1128.
26. Perillo NL, Pace KE, Seilhamer JJ and Baum LG: Apoptosis of T cells mediated by galectin-1. Nature (1995) 378, 736-739.
27. Perillo NL, Marcus ME, Baum LG: Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol Med (1998) 76, 402-412.
28. Allen HJ, Sucato D, Woynarowska B, Gottstine S, Sharma A and Bernacki RJ: Role of galaptin in ovarian carcinoma adhesion to extracellular matrix in vitro. J Cell Biochem (1990) 43, 43-57.
29. Cooper DN, Massa SM and Barondes SH: Endogenous muscle lectin inhibits myoblast adhesion to laminin. J Cell Biol (1991) 115, 1437-1448.
30. Kuwabara I and Liu F-T: Galectin-3 promotes adhesion of human neutrophils to laminin. J Immunol (1996) 156, 3939-3944.
31. van den Brule FA, Buicu C, Sobel ME, Liu F-T and Castronovo V: Galectin-3, a laminin binding protein, fails to modulate adhesion of human melanoma cells to laminin. Neoplasma (1995) 42, 215-219.
32. Ochieng J, Leite-Browning ML and Warfield P: Regulation of cellular adhesion to extracellular matrix proteins by galectin-3. Biochem Biophys Res Commun (1998) 246, 788-791.
33. Yamaoka K, Ohno S, Kawasaki H and Suzuki K: Overexpression of a β-galactoside-binding protein causes transformation of BALB3T3 fibroblast cells. Biochem Biophys Res Commun (1991) 179, 272-279.
34. Wells V and Mallucci L: Identification of an autocrine negative growth factor: Mouse β-galactoside-binding protein is a cytostatic factor and cell growth regulator. Cell (1991) 64, 91-97.
35. Adams L, Scott GK and Weinberg CS: Biphasic modulation of cell growth by recombinant human galectin-1. Biochim Biophys Acta (1996) 1312, 137-144.
36. Xu XC, el-Naggar AK and Lotan R: Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications. Am J Pathol (1995) 147, 815-822.
37. Castronovo V, Van Den Brule FA, Jackers P, Clausse N, Liu F-T, Gillet C and Sobel ME: Decreased expression of galectin-3 is associated with progression of human breast cancer. J Pathol (1995) 179, 43-48.
38. Raz A, Zhu DG, Hogan V, Shah N, Raz T, Karkash R, Pazerini G and Carmi P: Evidence for the role of 34-kDa galactoside-binding lectin in transformation and metastasis, Int J Cancer (1990) 46, 871-877.
39. Lotz MM, Andrews CW Jr, Korzelius CA, Lee EC, Steele GD Jr, Clarke A and Mercurio AM: Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc Natl Acad Sci USA (1993) 90, 3466-3470.
40. Hirabayashi J and Kasai K: Human placenta β-galactoside-binding lectin. Purification and some properties. Biochem Biophys Res Commun (1984) 122, 938-944.
41. Yamaoka K, Mishima K, Nagashima Y, Asai A, Sanai Y and Kirino T: Expression of galectin-1 mRNA correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells. J Neurosci Res (2000) 59, 722-730.
42. Levi G, Tarrab-Hazdai R and Teichberg VI: Prevention and therapy with electrolectin of experimental autoimmune myasthenia gravis in rabbits. Eur J Immunol (1983) 13, 500-507.
43. Offner H, Celnik B, Bringman TS, Casentini-Borocz D, Nedwin GE and Vandenbark AA: Recombinant human β-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis. J Neuroimmunol (1990) 28, 177-184.
44. Perillo NL, Uittenbogaart CH, Nguyen JT and Baum LG: Galectin-1, an endogenous lectin produced by thymic epithelial cells, induces apoptosis of human thymocytes. J Exp Med (1997) 185, 1851-1858.
45. 2+ thymocytes as post-selection intermediates leading to mature T cells. J Exp Med (1991) 173, 323-332.
46. Ong CJ, Chui D, Teh HS and Marth JD: Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection. J Immunol (1994) 152, 3793-3805.
47. Yang RY, Hsu DK and Liu F-T: Expression of galectin-3 modulates T cell growth and apoptosis. Proc Natl Acad Sci USA (1996) 93, 6737-6742.
48. Rabinovich GA, Daly G, Dreja H, Riera CM, Hirabayashi J and Chernajovsky Y: Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. J Exp Med (1999) 190 (3), 385-398.
49. Tsuchiyama Y, Wada J, Zhang H, Morita Y, Hiragushi K, Hida K, Shikata K, Yamamura M, Kanwar YS, Makino H: Efficacy of galectins in the amelioration of nephrotoxic serum nephritis in WKY rats. Kidney Int (2000) 58(5), 1941-1952.
50. Sato S and Hughes RC: Regulation of secretion and surface expression of Mac-2, a galactoside-binding protein of macrophages. J Biol Chem (1994) 269, 4424-4430.
51. Rabinovich GA, Iglesias MM, Modesti NM, Castagna LF, Wolfenstein-Todel C, Riera CM and Sotomayor CE: Activated rat macrophages produce a galectin-1-like protein that induces apoptpsis of T cells: Biochemical and functional characterization. J Immunol (1998) 160, 4831-4840.
52. Yamaoka A, Kuwabara I, Frigeri LG and Liu F-T: A human lectin, galectin-3 (εbp/Mac-2), stimulates superoxide production by neutrophils. J Immunol (1995) 154, 3479-3487.
53. Colnot C, Ripoche MA, Milon G, Montagutelli X, Crocker PR and Poirier F: Maintenance of granulocyte numbers during acute peritonitis is defective in galectin-3-null mutant mice. Immunology (1998) 94, 290-296.
54. Nachtigal M, Al-Assaad Z, Mayer EP, Kim K and Monsigny M: Galectin-3 expression in human atherosclerotic lesions. Am J pathol (1998) 152, 1199-1208.
55. Vlassara H, Li YM, Imani F, Wojciechowicz D, Yang Z, Liu F-T and Cerami A: Identification of galectin-3 as a high-affinity binding protein for advanced glycation end products (AGE): A new member of the AGE-receptor complex. Mol Med (1995) 1, 634-646.
56. Pugliese G, Pricci F, Leto G, Amadio L, lacobini C, Romeo G, Lenti L, Sale P, Gradini R, Liu F-T and Di Mario U: The diabetic milieu modulates the advanced glycation end product-receptor complex in mesangium by inducing or upregulating galectin-3 expression. Diabetes (2000) 49, 1249-1257.