Morphine and galectin-1 modulate HIV-1 infection of human monocyte-derived macrophages

Journal of Immunology

Volumn 188, Issue 8, 2012, Pages 3757-3765

  Reynolds, Jessica L ^a   Law, Wing Cheung ^b   Mahajan, Supriya D ^a   Aalinkeel, Ravikumar ^a   Nair, Bindukumar ^a   Sykes, Donald E ^a   Mammen, Manoj J ^a   Yong, Ken Tye ^c   Hui, Rui ^b   Prasad, Paras N ^b   Schwartz, Stanley A ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; GALECTIN 1; GOLD NANOPARTICLE; MORPHINE; NANOROD; SMALL INTERFERING RNA;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOMODULATION; MACROPHAGE; MONOCYTE DERIVED MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; VIRUS INFECTIVITY; VIRUS REPLICATION;

CELL SURVIVAL; CELLS, CULTURED; GALECTIN 1; GENE EXPRESSION; GENE SILENCING; GOLD; HIV INFECTIONS; HIV-1; HUMANS; MACROPHAGES; MORPHINE; NANOTUBES; NARCOTICS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VIRAL LOAD;

EID: 84860324530     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1102276     Document Type: Article

References (57)

1. Hamamoto, D. T., and N. L. Rhodus. 2009. Methamphetamine abuse and dentistry. Oral Dis. 15: 27-37.
2. Liang, H., X. Wang, H. Chen, L. Song, L. Ye, S. H. Wang, Y. J. Wang, L. Zhou, and W. Z. Ho. 2008. Methamphetamine enhances HIV infection of macrophages. Am. J. Pathol. 172: 1617-1624. (Pubitemid 351793354)
3. Toussi, S. S., A. Joseph, J. H. Zheng, M. Dutta, L. Santambrogio, and H. Goldstein. 2009. Short communication: Methamphetamine treatment increases in vitro and in vivo HIV replication. AIDS Res. Hum. Retroviruses 25: 1117-1121.
4. Roth, M. D., K. M. Whittaker, R. Choi, D. P. Tashkin, and G. C. Baldwin. 2005. Cocaine and sigma-1 receptors modulate HIV infection, chemokine receptors, and the HPA axis in the huPBL-SCID model. J. Leukoc. Biol. 78: 1198-1203. (Pubitemid 41779224)
5. Guo, C. J., Y. Li, S. Tian, X. Wang, S. D. Douglas, and W. Z. Ho. 2002. Morphine enhances HIV infection of human blood mononuclear phagocytes through modulation of beta-chemokines and CCR5 receptor. J. Investig. Med. 50: 435-442. (Pubitemid 35278684)
6. Le Douce, V., G. Herbein, O. Rohr, and C. Schwartz. 2010. Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage. Retrovirology 7: 32.
7. Herbein, G., and A. Varin. 2010. The macrophage in HIV-1 infection: from activation to deactivation? Retrovirology 7: 33.
8. Bergamaschi, A., and G. Pancino. 2010. Host hindrance to HIV-1 replication in monocytes and macrophages. Retrovirology 7: 31.
9. Crowe, S., T. Zhu, and W. A. Muller. 2003. The contribution of monocyte infection and trafficking to viral persistence, and maintenance of the viral reservoir in HIV infection. J. Leukoc. Biol. 74: 635-641. (Pubitemid 38040338)
10. Gilbert, C., R. Cantin, C. Barat, and M. J. Tremblay. 2007. Human immunodeficiency virus type 1 replication in dendritic cell-T-cell cocultures is increased upon incorporation of host LFA-1 due to higher levels of virus production in immature dendritic cells. J. Virol. 81: 7672-7682. (Pubitemid 47047852)
11. Fortin, J. F., R. Cantin, and M. J. Tremblay. 1998. T cells expressing activated LFA-1 are more susceptible to infection with human immunodeficiency virus type 1 particles bearing host-encoded ICAM-1. J. Virol. 72: 2105-2112. (Pubitemid 28100766)
12. Barondes, S. H., D. N. Cooper, M. A. Gitt, and H. Leffler. 1994. Galectins. Structure and function of a large family of animal lectins. J. Biol. Chem. 269: 20807-20810.
13. Chiariotti, L., P. Salvatore, R. Frunzio, and C. B. Bruni. 2004. Galectin genes: regulation of expression. Glycoconj. J. 19: 441-449. (Pubitemid 38316517)
14. Liu, F. T. 2002. Galectins: novel anti-inflammatory drug targets. Expert Opin. Ther. Targets 6: 461-468.
15. Elola, M. T., M. E. Chiesa, A. F. Alberti, J. Mordoh, and N. E. Fink. 2005. Galectin-1 receptors in different cell types. J. Biomed. Sci. 12: 13-29. (Pubitemid 40584806)
16. Almkvist, J., and A. Karlsson. 2004. Galectins as inflammatory mediators. Glycoconj. J. 19: 575-581. (Pubitemid 38316532)
17. Scott, K., and C. Weinberg. 2004. Galectin-1: a bifunctional regulator of cellular proliferation. Glycoconj. J. 19: 467-477.
18. Ouellet, M., S. Mercier, I. Pelletier, S. Bounou, J. Roy, J. Hirabayashi, S. Sato, and M. J. Tremblay. 2005. Galectin-1 acts as a soluble host factor that promotes HIV-1 infectivity through stabilization of virus attachment to host cells. J. Immunol. 174: 4120-4126. (Pubitemid 40395989)
19. Mercier, S., C. St-Pierre, I. Pelletier, M. Ouellet, M. J. Tremblay, and S. Sato. 2008. Galectin-1 promotes HIV-1 infectivity in macrophages through stabilization of viral adsorption. Virology 371: 121-129.
20. St-Pierre, C., M. Ouellet, M. J. Tremblay, and S. Sato. 2010. Galectin-1 and HIV-1 Infection. Methods Enzymol. 480: 267-294.
21. Reynolds, J. L., S. D. Mahajan, D. E. Sykes, S. A. Schwartz, and M. P. Nair. 2007. Proteomic analyses of methamphetamine (METH)-induced differential protein expression by immature dendritic cells (IDC). Biochim. Biophys. Acta 1774: 433-442. (Pubitemid 46498837)
22. Bonoiu, A. C., S. D. Mahajan, H. Ding, I. Roy, K. T. Yong, R. Kumar, R. Hu, E. J. Bergey, S. A. Schwartz, and P. N. Prasad. 2009. Nanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons. Proc. Natl. Acad. Sci. USA 106: 5546-5550.
23. Prasad, P. N. 2004. Introduction to Biophotonics. Wiley, New York.
24. Connor, E. E., J. Mwamuka, A. Gole, C. J. Murphy, and M. D. Wyatt. 2005. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small 1: 325-327. (Pubitemid 43951781)
25. Ghosh, P., G. Han, M. De, C. K. Kim, and V. M. Rotello. 2008. Gold nanoparticles in delivery applications. Adv. Drug Deliv. Rev. 60: 1307-1315.
26. Ding, H., K. T. Yong, I. Roy, H. E. Pudavar, W. C. Law, E. J. Bergey, and P. N. Prasad. 2007. Gold nanorods coated with multilayer polyelectrolyte as contrast agents for multimodal imaging. J. Phys. Chem. C 111: 12552-12557. (Pubitemid 47388082)
27. Sokolov, K., M. Follen, J. Aaron, I. Pavlova, A. Malpica, R. Lotan, and R. Richards-Kortum. 2003. Real-time vital optical imaging of precancer using anti-epidermal growth factor receptor antibodies conjugated to gold nanoparticles. Cancer Res. 63: 1999-2004. (Pubitemid 36538596)
28. Mahajan, S. D., S. A. Schwartz, T. C. Shanahan, R. P. Chawda, and M. P. Nair. 2002. Morphine regulates gene expression of alpha- and beta-chemokines and their receptors on astroglial cells via the opioid mu receptor. J. Immunol. 169: 3589-3599.
29. Mahajan, S. D., S. A. Schwartz, R. Aalinkeel, R. P. Chawda, D. E. Sykes, and M. P. Nair. 2005. Morphine modulates chemokine gene regulation in normal human astrocytes. Clin. Immunol. 115: 323-332. (Pubitemid 40716049)
30. Bustin, S. A. 2002. Quantification of mRNA using real-time reverse transcription PCR (RT-PCR): trends and problems. J. Mol. Endocrinol. 29: 23-39. (Pubitemid 34965744)
31. Radonić, A., S. Thulke, I. M. Mackay, O. Landt, W. Siegert, and A. Nitsche. 2004. Guideline to reference gene selection for quantitative real-time PCR. Biochem. Biophys. Res. Commun. 313: 856-862. (Pubitemid 38050071)
32. Trikha, S., and A. M. Jeremic. 2011. Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol. J. Biol. Chem. 286: 36086-36097.
33. Kumar, U., D. Laird, C. B. Srikant, E. Escher, and Y. C. Patel. 1997. Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy. Endocrinology 138: 4473-4476. (Pubitemid 27408496)
34. Balkundi, S., A. S. Nowacek, U. Roy, A. Martinez-Skinner, J. McMillan, and H. E. Gendelman. 2010. Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs. J. Vis. Exp. (46). pii: 2460.
35. Gaskill, P. J., T. M. Calderon, A. J. Luers, E. A. Eugenin, J. A. Javitch, and J. W. Berman. 2009. Human immunodeficiency virus (HIV) infection of human macrophages is increased by dopamine: a bridge between HIV-associated neurologic disorders and drug abuse. Am. J. Pathol. 175: 1148-1159.
36. Secchiero, P., D. Zella, S. Curreli, P. Mirandola, S. Capitani, R. C. Gallo, and G. Zauli. 2000. Engagement of CD28 modulates CXC chemokine receptor 4 surface expression in both resting and CD3-stimulated CD4+ T cells. J. Immunol. 164: 4018-4024. (Pubitemid 30215055)
37. Chang, S. L., and K. P. Connaghan. 2011. Behavioral and Molecular Evidence for a Feedback Interaction Between Morphine and HIV-1 Viral Proteins. J. Neuroimmune Pharmacol. DOI: 10.1007/s11481-011-9324-1.
38. Avdoshina, V., F. Biggio, G. Palchik, L. A. Campbell, and I. Mocchetti. 2010. Morphine induces the release of CCL5 from astrocytes: potential neuroprotective mechanism against the HIV protein gp120. Glia 58: 1630-1639.
39. Reynolds, J. L., S. D. Mahajan, D. Sykes, and M. P. Nair. 2006. Heroin-Induces Differential Protein Expression by Normal Human Astrocytes (NHA). Am. J. Infect. Dis. 2: 49-57.
40. Martin, J. L., L. Koodie, A. G. Krishnan, R. Charboneau, R. A. Barke, and S. Roy. 2010. Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site. Am. J. Pathol. 176: 786-799.
41. Vojdani, Z., F. Dehghani, F. Seyedi, A. Noorafshan, and F. Baha-al-din Bagi. 2010. Quantitative study of the effects of morphine on the mouse spleen and inguinal lymph node. Arch. Iran Med. 13: 294-300.
42. Van der Laan, J. W., H. Timmerman, and H. Van Loveren. 1996. Comparison of the in vivo effects of morphine and methadone on natural killer cell activity in spleen, peritoneal cavity, and lungs in rats. Int. J. Immunopharmacol. 18: 401-407. (Pubitemid 27033238)
43. Beagles, K., A. Wellstein, and B. Bayer. 2004. Systemic morphine administration suppresses genes involved in antigen presentation. Mol. Pharmacol. 65: 437-442. (Pubitemid 38134272)
44. Peterson, P. K., B. M. Sharp, G. Gekker, P. S. Portoghese, K. Sannerud, and H. H. Balfour, Jr. 1990. Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cocultures. AIDS 4: 869-873. (Pubitemid 20342117)
45. Peterson, P. K., G. Gekker, S. Hu, G. Cabral, and J. R. Lokensgard. 2004. Cannabinoids and morphine differentially affect HIV-1 expression in CD4(+) lymphocyte and microglial cell cultures. J. Neuroimmunol. 147: 123-126. (Pubitemid 38114961)
46. Peterson, P. K., G. Gekker, S. Hu, W. R. Anderson, F. Kravitz, P. S. Portoghese, H. H. Balfour, Jr., and C. C. Chao, Jr. 1994. Morphine amplifies HIV-1 expression in chronically infected promonocytes cocultured with human brain cells. J. Neuroimmunol. 50: 167-175. (Pubitemid 24071782)
47. Schweitzer, C., F. Keller, M. P. Schmitt, D. Jaeck, M. Adloff, C. Schmitt, C. Royer, A. Kirn, and A. M. Aubertin. 1991. Morphine stimulates HIV replication in primary cultures of human Kupffer cells. Res. Virol. 142: 189-195.
48. Li, Y., J. D. Merrill, K. Mooney, L. Song, X. Wang, C. J. Guo, R. C. Savani, D. S. Metzger, S. D. Douglas, and W. Z. Ho. 2003. Morphine enhances HIV infection of neonatal macrophages. Pediatr. Res. 54: 282-288. (Pubitemid 36918165)
49. Ho, W. Z., C. J. Guo, C. S. Yuan, S. D. Douglas, and J. Moss. 2003. Methylnaltrexone antagonizes opioid-mediated enhancement of HIV infection of human blood mononuclear phagocytes. J. Pharmacol. Exp. Ther. 307: 1158-1162. (Pubitemid 37494237)
50. Rabinovich, G. A., C. M. Riera, and C. E. Sotomayor. 1999. Galectin-1, an alternative signal for T cell death, is increased in activated macrophages. Braz. J. Med. Biol. Res. 32: 557-567. (Pubitemid 129540418)
51. Barrionuevo, P., M. Beigier-Bompadre, J. M. Ilarregui, M. A. Toscano, G. A. Bianco, M. A. Isturiz, and G. A. Rabinovich. 2007. A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway. J. Immunol. 178: 436-445. (Pubitemid 46033627)
52. Brandt, B., E. F. Abou-Eladab, M. Tiedge, and H. Walzel. 2010. Role of the JNK/c-Jun/AP-1 signaling pathway in galectin-1-induced T-cell death. Cell Death Dis 1: e23.
53. Gieseke, F., J. Böhringer, R. Bussolari, M. Dominici, R. Handgretinger, and I. Müller. 2010. Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells. Blood 116: 3770-3779.
54. Endharti, A. T., Y. W. Zhou, I. Nakashima, and H. Suzuki. 2005. Galectin-1 supports survival of naive T cells without promoting cell proliferation. Eur. J. Immunol. 35: 86-97. (Pubitemid 40123855)
55. Rabinovich, G. A., A. Ariel, R. Hershkoviz, J. Hirabayashi, K. I. Kasai, and O. Lider. 1999. Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1. Immunology 97: 100-106. (Pubitemid 29217266)
56. Romagnani, S. 2000. T-cell subsets (Th1 versus Th2). Ann. Allergy Asthma Immunol. 85: 9-18, quiz 18, 21.
57. Romagnani, P., F. Annunziato, M. P. Piccinni, E. Maggi, and S. Romagnani. 2000. Th1/Th2 cells, their associated molecules and role in pathophysiology. Eur. Cytokine Netw. 11: 510-511.