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Volumn 23, Issue 2, 2016, Pages 231-241

Reduced mitochondrial Ca 2+ transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE ND5; UNCLASSIFIED DRUG; CALCIUM; CALCIUM CHANNEL; MITOCHONDRIAL CALCIUM UNIPORTER; MITOCHONDRIAL PROTEIN; ND5 PROTEIN, HUMAN; PROTEIN SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 84954075359     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2015.84     Document Type: Article
Times cited : (53)

References (52)
  • 1
    • 4944260285 scopus 로고    scopus 로고
    • Mitochondrial disorders
    • Zeviani M, Di Donato S. Mitochondrial disorders. Brain 2004; 127: 2153-2172.
    • (2004) Brain , vol.127 , pp. 2153-2172
    • Zeviani, M.1    Di Donato, S.2
  • 2
    • 54949142139 scopus 로고    scopus 로고
    • Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: Basic concepts, clinical phenotype, and therapeutic management of MELAS syndrome
    • Sproule DM, Kaufmann P. Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: basic concepts, clinical phenotype, and therapeutic management of MELAS syndrome. Ann NY Acad Sci 2008; 1142: 133-158.
    • (2008) Ann NY Acad Sci , vol.1142 , pp. 133-158
    • Sproule, D.M.1    Kaufmann, P.2
  • 6
    • 77955041880 scopus 로고    scopus 로고
    • Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
    • Cardenas C, Miller RA, Smith I, Bui T, Molgo J, Muller M et al. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria. Cell 2010; 142: 270-283.
    • (2010) Cell , vol.142 , pp. 270-283
    • Cardenas, C.1    Miller, R.A.2    Smith, I.3    Bui, T.4    Molgo, J.5    Muller, M.6
  • 7
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008; 132: 27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 8
    • 77955398958 scopus 로고    scopus 로고
    • Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
    • Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ. Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells. Proc Natl Acad Sci USA 2010; 107: 11835-11840.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11835-11840
    • Suen, D.F.1    Narendra, D.P.2    Tanaka, A.3    Manfredi, G.4    Youle, R.J.5
  • 10
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183: 795-803.
    • (2008) J Cell Biol , vol.183 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 11
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122: 927-939.
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 12
    • 80051936634 scopus 로고    scopus 로고
    • A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
    • De Stefani D, Raffaello A, Teardo E, Szabo I, Rizzuto R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 2011; 476: 336-340.
    • (2011) Nature , vol.476 , pp. 336-340
    • De Stefani, D.1    Raffaello, A.2    Teardo, E.3    Szabo, I.4    Rizzuto, R.5
  • 13
    • 80051946060 scopus 로고    scopus 로고
    • Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
    • Baughman JM, Perocchi F, Girgis HS, Plovanich M, Belcher-Timme CA, Sancak Y et al. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 2011; 476: 341-345.
    • (2011) Nature , vol.476 , pp. 341-345
    • Baughman, J.M.1    Perocchi, F.2    Girgis, H.S.3    Plovanich, M.4    Belcher-Timme, C.A.5    Sancak, Y.6
  • 14
    • 84883286784 scopus 로고    scopus 로고
    • The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
    • Raffaello A, De Stefani D, Sabbadin D, Teardo E, Merli G, Picard A et al. The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit. EMBO J 2013; 32: 2362-2376.
    • (2013) EMBO J , vol.32 , pp. 2362-2376
    • Raffaello, A.1    De Stefani, D.2    Sabbadin, D.3    Teardo, E.4    Merli, G.5    Picard, A.6
  • 16
    • 84868027665 scopus 로고    scopus 로고
    • MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival
    • Mallilankaraman K, Doonan P, Cardenas C, Chandramoorthy HC, Muller M, Miller R et al. MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival. Cell 2012; 151: 630-644.
    • (2012) Cell , vol.151 , pp. 630-644
    • Mallilankaraman, K.1    Doonan, P.2    Cardenas, C.3    Chandramoorthy, H.C.4    Muller, M.5    Miller, R.6
  • 18
    • 84878796986 scopus 로고    scopus 로고
    • MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca(2)(+) uniporter
    • Csordas G, Golenar T, Seifert EL, Kamer KJ, Sancak Y, Perocchi F et al. MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca(2)(+) uniporter. Cell Metab 2013; 17: 976-987.
    • (2013) Cell Metab , vol.17 , pp. 976-987
    • Csordas, G.1    Golenar, T.2    Seifert, E.L.3    Kamer, K.J.4    Sancak, Y.5    Perocchi, F.6
  • 19
    • 84896703008 scopus 로고    scopus 로고
    • MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity
    • Patron M, Checchetto V, Raffaello A, Teardo E, Vecellio Reane D, Mantoan M et al. MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity. Mol Cell 2014; 53: 726-737.
    • (2014) Mol Cell , vol.53 , pp. 726-737
    • Patron, M.1    Checchetto, V.2    Raffaello, A.3    Teardo, E.4    Vecellio Reane, D.5    Mantoan, M.6
  • 20
    • 84896262743 scopus 로고    scopus 로고
    • SLC25A23 augments mitochondrial Ca(2)(+) uptake, interacts with MCU, and induces oxidative stress-mediated cell death
    • Hoffman NE, Chandramoorthy HC, Shanmughapriya S, Zhang XQ, Vallem S, Doonan PJ et al. SLC25A23 augments mitochondrial Ca(2)(+) uptake, interacts with MCU, and induces oxidative stress-mediated cell death. Mol Biol Cell 2014; 25: 936-947.
    • (2014) Mol Biol Cell , vol.25 , pp. 936-947
    • Hoffman, N.E.1    Chandramoorthy, H.C.2    Shanmughapriya, S.3    Zhang, X.Q.4    Vallem, S.5    Doonan, P.J.6
  • 21
    • 68649090226 scopus 로고    scopus 로고
    • Regulation of mitochondrial dehydrogenases by calcium ions
    • Denton RM. Regulation of mitochondrial dehydrogenases by calcium ions. Biochim Biophys Acta 2009; 1787: 1309-1316.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 1309-1316
    • Denton, R.M.1
  • 22
    • 0033598828 scopus 로고    scopus 로고
    • Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming
    • Jouaville LS, Pinton P, Bastianutto C, Rutter GA, Rizzuto R. Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic priming. Proc Natl Acad Sci USA 1999; 96: 13807-13812.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13807-13812
    • Jouaville, L.S.1    Pinton, P.2    Bastianutto, C.3    Rutter, G.A.4    Rizzuto, R.5
  • 23
    • 84883776628 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore: A mystery solved?
    • Bernardi P. The mitochondrial permeability transition pore: a mystery solved? Front Physiol 2013; 4: 95.
    • (2013) Front Physiol , vol.4 , pp. 95
    • Bernardi, P.1
  • 24
    • 80052627393 scopus 로고    scopus 로고
    • Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis
    • Rasola A, Bernardi P. Mitochondrial permeability transition in Ca(2+)-dependent apoptosis and necrosis. Cell Calcium 2011; 50: 222-233.
    • (2011) Cell Calcium , vol.50 , pp. 222-233
    • Rasola, A.1    Bernardi, P.2
  • 27
    • 34447636774 scopus 로고    scopus 로고
    • Novel mutations of ND genes in complex I deficiency associated with mitochondrial encephalopathy
    • Malfatti E, Bugiani M, Invernizzi F, de Souza CF, Farina L, Carrara F et al. Novel mutations of ND genes in complex I deficiency associated with mitochondrial encephalopathy. Brain 2007; 130: 1894-1904.
    • (2007) Brain , vol.130 , pp. 1894-1904
    • Malfatti, E.1    Bugiani, M.2    Invernizzi, F.3    De Souza, C.F.4    Farina, L.5    Carrara, F.6
  • 29
    • 84892859905 scopus 로고    scopus 로고
    • Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy
    • Rogov V, Dotsch V, Johansen T, Kirkin V. Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy. Mol Cell 2014; 53: 167-178.
    • (2014) Mol Cell , vol.53 , pp. 167-178
    • Rogov, V.1    Dotsch, V.2    Johansen, T.3    Kirkin, V.4
  • 31
    • 34250811414 scopus 로고    scopus 로고
    • The role of autophagy in mitochondria maintenance: Characterization of mitochondrial functions in autophagy-deficient S. Cerevisiae strains
    • Zhang Y, Qi H, Taylor R, Xu W, Liu LF, Jin S. The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains. Autophagy 2007; 3: 337-346.
    • (2007) Autophagy , vol.3 , pp. 337-346
    • Zhang, Y.1    Qi, H.2    Taylor, R.3    Xu, W.4    Liu, L.F.5    Jin, S.6
  • 32
    • 80052145606 scopus 로고    scopus 로고
    • A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery
    • Katayama H, Kogure T, Mizushima N, Yoshimori T, Miyawaki A. A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery. Chem Biol 2011; 18: 1042-1052.
    • (2011) Chem Biol , vol.18 , pp. 1042-1052
    • Katayama, H.1    Kogure, T.2    Mizushima, N.3    Yoshimori, T.4    Miyawaki, A.5
  • 33
    • 84868575932 scopus 로고    scopus 로고
    • Mitochondrial quality control mediated by PINK1 and Parkin: Links to parkinsonism
    • Narendra D, Walker JE, Youle R. Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harb Perspect Biol 2012; 4: 11.
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 11
    • Narendra, D.1    Walker, J.E.2    Youle, R.3
  • 34
    • 84901471156 scopus 로고    scopus 로고
    • Parkin and mitochondrial quality control: Toward assembling the puzzle
    • Winklhofer KF. Parkin and mitochondrial quality control: toward assembling the puzzle. Trends Cell Biol 2014; 24: 332-341.
    • (2014) Trends Cell Biol , vol.24 , pp. 332-341
    • Winklhofer, K.F.1
  • 35
    • 0032773120 scopus 로고    scopus 로고
    • A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency
    • Brini M, Pinton P, King MP, Davidson M, Schon EA, Rizzuto R. A calcium signaling defect in the pathogenesis of a mitochondrial DNA inherited oxidative phosphorylation deficiency. Nat Med 1999; 5: 951-954.
    • (1999) Nat Med , vol.5 , pp. 951-954
    • Brini, M.1    Pinton, P.2    King, M.P.3    Davidson, M.4    Schon, E.A.5    Rizzuto, R.6
  • 36
    • 0028901688 scopus 로고
    • Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation
    • Brini M, Marsault R, Bastianutto C, Alvarez J, Pozzan T, Rizzuto R. Transfected aequorin in the measurement of cytosolic Ca2+ concentration ([Ca2+]c). A critical evaluation. J Biol Chem 1995; 270: 9896-9903.
    • (1995) J Biol Chem , vol.270 , pp. 9896-9903
    • Brini, M.1    Marsault, R.2    Bastianutto, C.3    Alvarez, J.4    Pozzan, T.5    Rizzuto, R.6
  • 37
    • 0026659512 scopus 로고
    • Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin
    • Rizzuto R, Simpson AW, Brini M, Pozzan T. Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. Nature 1992; 358: 325-327.
    • (1992) Nature , vol.358 , pp. 325-327
    • Rizzuto, R.1    Simpson, A.W.2    Brini, M.3    Pozzan, T.4
  • 38
    • 0028832662 scopus 로고
    • Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells
    • Montero M, Brini M, Marsault R, Alvarez J, Sitia R, Pozzan T et al. Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells. EMBO J 1995; 14: 5467-5475.
    • (1995) EMBO J , vol.14 , pp. 5467-5475
    • Montero, M.1    Brini, M.2    Marsault, R.3    Alvarez, J.4    Sitia, R.5    Pozzan, T.6
  • 39
    • 34648828532 scopus 로고    scopus 로고
    • AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
    • Hardie DG. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat Rev Mol Cell Biol 2007; 8: 774-785.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 774-785
    • Hardie, D.G.1
  • 41
    • 57349100367 scopus 로고    scopus 로고
    • Mitofusin 2 tethers endoplasmic reticulum to mitochondria
    • de Brito OM, Scorrano L. Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 2008; 456: 605-610.
    • (2008) Nature , vol.456 , pp. 605-610
    • De Brito, O.M.1    Scorrano, L.2
  • 43
    • 0036884142 scopus 로고    scopus 로고
    • A novel regulatory mechanism of the mitochondrial Ca2+ uniporter revealed by the p38 mitogen-activated protein kinase inhibitor SB202190
    • Montero M, Lobaton CD, Moreno A, Alvarez J. A novel regulatory mechanism of the mitochondrial Ca2+ uniporter revealed by the p38 mitogen-activated protein kinase inhibitor SB202190. FASEB J 2002; 16: 1955-1957.
    • (2002) FASEB J , vol.16 , pp. 1955-1957
    • Montero, M.1    Lobaton, C.D.2    Moreno, A.3    Alvarez, J.4
  • 44
    • 54949110895 scopus 로고    scopus 로고
    • Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
    • Pinton P, Giorgi C, Siviero R, Zecchini E, Rizzuto R. Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis. Oncogene 2008; 27: 6407-6418.
    • (2008) Oncogene , vol.27 , pp. 6407-6418
    • Pinton, P.1    Giorgi, C.2    Siviero, R.3    Zecchini, E.4    Rizzuto, R.5
  • 45
    • 65449139544 scopus 로고    scopus 로고
    • Mitochondria, calcium and cell death: A deadly triad in neurodegeneration
    • Celsi F, Pizzo P, Brini M, Leo S, Fotino C, Pinton P et al. Mitochondria, calcium and cell death: a deadly triad in neurodegeneration. Biochim Biophys Acta 2009; 1787: 335-344.
    • (2009) Biochim Biophys Acta , vol.1787 , pp. 335-344
    • Celsi, F.1    Pizzo, P.2    Brini, M.3    Leo, S.4    Fotino, C.5    Pinton, P.6
  • 48
    • 77956255221 scopus 로고    scopus 로고
    • Molecular genetics of mitochondrial disorders
    • Wong LJ. Molecular genetics of mitochondrial disorders. Dev Disabil Res Rev 2010; 16: 154-162.
    • (2010) Dev Disabil Res Rev , vol.16 , pp. 154-162
    • Wong, L.J.1
  • 49
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 50
    • 0024448458 scopus 로고
    • Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
    • King MP, Attardi G. Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 1989; 246: 500-503.
    • (1989) Science , vol.246 , pp. 500-503
    • King, M.P.1    Attardi, G.2
  • 51
    • 84873254580 scopus 로고    scopus 로고
    • Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics
    • Cali T, Ottolini D, Negro A, Brini M. Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics. Biochim Biophys Acta 2013; 1832: 495-508.
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 495-508
    • Cali, T.1    Ottolini, D.2    Negro, A.3    Brini, M.4
  • 52


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