High Potency of a Novel Resveratrol Derivative, 3,3′,4,4′-Tetrahydroxy-trans-stilbene, against Ovarian Cancer Is Associated with an Oxidative Stress-Mediated Imbalance between DNA Damage Accumulation and Repair

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Mikuła Pietrasik, Justyna ^a   Sosińska, Patrycja ^a   Murias, Marek ^a   Wierzchowski, Marcin ^a   Brewińska Olchowik, Marta ^b   Piwocka, Katarzyna ^b   Szpurek, Dariusz ^a   Ksiązek, Krzysztof ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL PROLIFERATION; CYTOLOGY; DISEASES; DNA; ENZYMES; OXYGEN; REPAIR; RESVERATROL; ROAD CONSTRUCTION;

DNA GLYCOSYLASE; MECHANISTIC ASPECTS; OVARIAN CANCER CELLS; OVARIAN CANCERS; OXIDATIVE STRESS-DEPENDENT; REACTIVE OXYGEN SPECIES; SUPER OXIDE DISMUTASE; TRANS-STILBENE;

CELLS;

3,3',4,4' TETRAHYDROXY TRANS STILBENE; 8 HYDROXYDEOXYGUANOSINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; DNA GLYCOSYLTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; RESVERATROL; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; 3,3',4,4'-TETRAHYDROXYSTILBENE; 8-OXO-7-HYDRODEOXYGUANOSINE; CATECHOL DERIVATIVE; DEOXYGUANOSINE; PROTEIN KINASE INHIBITOR; STILBENE DERIVATIVE;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; ENZYME ACTIVITY; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INCIDENCE; OVARY CANCER; OXIDATIVE STRESS; SENESCENCE; ADULT; ANALOGS AND DERIVATIVES; CHEMISTRY; DRUG EFFECTS; FEMALE; METABOLISM; OVARY TUMOR; PATHOLOGY; TUMOR CELL LINE;

ADULT; APOPTOSIS; CASPASE 3; CASPASE 8; CASPASE 9; CATALASE; CATECHOLS; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYGUANOSINE; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; FEMALE; HUMANS; OVARIAN NEOPLASMS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; REACTIVE OXYGEN SPECIES; STILBENES; SUPEROXIDE DISMUTASE;

EID: 84953923910     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/135691     Document Type: Article

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