Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination

Nature Communications

Volumn 7, Issue , 2016, Pages

  Fourati, Slim ^a,b   Cristescu, Razvan ^c   Loboda, Andrey ^c   Talla, Aarthi ^a,b   Filali, Ali ^a,b   Railkar, Radha ^c   Schaeffer, Andrea K ^c   Favre, David ^d   Gagnon, Dominic ^d   Peretz, Yoav ^d   Wang, I Ming ^c   Beals, Chan R ^c   Casimiro, Danilo R ^c   Carayannopoulos, Leonidas N ^c   Sékaly, Rafick Pierre ^a,b  

^a Vaccine and Gene Therapy Institute of Florida   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d Caprion/ImmuneCarta Services   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS B ANTIGEN; HEPATITIS VACCINE; BIOLOGICAL MARKER; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; TRANSCRIPTOME;

ADULT; FLOW CYTOMETRY; HEPATITIS; VACCINATION;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; CORRELATIONAL STUDY; ERYTHROCYTE; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HEPATITIS B; HUMAN; INFLAMMATION; MALE; NORMAL HUMAN; OBSERVATIONAL STUDY; OPEN STUDY; PREDICTION; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; VACCINATION; AGING; BLOOD; COHORT ANALYSIS; ERYTHROCYTE COUNT; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; VERY ELDERLY;

HEPATITIS B VIRUS;

ADULT; AGED; AGED, 80 AND OVER; AGING; B-LYMPHOCYTES; BIOMARKERS; COHORT STUDIES; ERYTHROCYTE COUNT; FEMALE; FLOW CYTOMETRY; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HUMANS; INFLAMMATION; MALE; MIDDLE AGED; TRANSCRIPTOME; VACCINATION;

EID: 84953911770     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10369     Document Type: Article

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