Combined targeted DNA sequencing in Non-Small Cell Lung Cancer (NSCLC) using UNCseq and NGScopy, and RNA sequencing using UNCqeR for the detection of genetic aberrations in NSCLC

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Zhao, Xiaobei ^a   Wang, Anyou ^a   Walter, Vonn ^a   Patel, Nirali M ^a,b   Eberhard, David A ^a,b   Hayward, Michele C ^a   Salazar, Ashley H ^a   Jo, Heejoon ^a,c   Soloway, Matthew G ^a   Wilkerson, Matthew D ^a,b   Parker, Joel S ^a   Yin, Xiaoying ^a   Zhang, Guosheng ^a   Siegel, Marni B ^b   Rosson, Gary B ^a,b   Earp, H Shelton ^a,b   Sharpless, Norman E ^a,b   Gulley, Margaret L ^a,b   Weck, Karen E ^a,b   Hayes, D Neil ^a,b   Moschos, Stergios J ^a,b   more..

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c IL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; B RAF KINASE; BRG1 PROTEIN; CBL PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HLA A ANTIGEN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE LKB1; PROTEIN P53; SMAD4 PROTEIN; VASCULOTROPIN RECEPTOR; KRAS PROTEIN, HUMAN; PROTEIN P21;

ADULT; AGED; ALGORITHM; ARID1A GENE; ARTICLE; ATM GENE; BRAF GENE; BRD3 GENE; CANCER GRADING; CANCER STAGING; CBL GENE; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; CTNNB1 GENE; DNA SEQUENCE; EGFR GENE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FBXW7 GENE; FEMALE; FGFR3 GENE; GENE; GENE DISRUPTION; GENETIC PARAMETERS; GOPC GENE; HLA A GENE; HUMAN; HUMAN TISSUE; KEAP1 GENE; KIAA0427 GENE; MAJOR CLINICAL STUDY; MALE; MLL2 GENE; NEXT GENERATION SEQUENCING; NF1 GENE; NFE2L2 GENE; NON SMALL CELL LUNG CANCER; NOTCH1 GENE; ONCOGENE K RAS; PIK3CA GENE; PPP2R1A GENE; PTEN GENE; RB1 GENE; RBM10 GENE; RNA SEQUENCE; SANGER SEQUENCE; SENSITIVITY AND SPECIFICITY; SETD2 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE NUCLEOTIDE VARIATION; SMAD4 GENE; SMARCA4 GENE; STK11 GENE; TP53 GENE; U2AF1 GENE; BIOLOGY; GENETIC ASSOCIATION STUDY; GENETIC VARIATION; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; LUNG TUMOR; MIDDLE AGED; MUTATION; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; COMPUTATIONAL BIOLOGY; DNA COPY NUMBER VARIATIONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTATION; NEOPLASM GRADING; NEOPLASM STAGING; PROTO-ONCOGENE PROTEINS P21(RAS); REPRODUCIBILITY OF RESULTS;

EID: 84953897271     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0129280     Document Type: Article

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