Mechanism of TiO2 nanoparticle-induced neurotoxicity in zebrafish (Danio rerio)

Environmental Toxicology

Volumn 31, Issue 2, 2016, Pages 163-175

  Sheng, Lei ^a   Wang, Ling ^b   Su, Mingyu ^a,c   Zhao, Xiaoyang ^a   Hu, Renping ^a   Yu, Xiaohong ^a   Hong, Jie ^a   Liu, Dong ^a   Xu, Bingqing ^a   Zhu, Yunting ^a   Wang, Han ^a   Hong, Fashui ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c Center Station of Suzhou Environmental Monitoring   (China)

Author keywords

Brain injury; Gene expression; Neurotransmitters; TiO2 nanoparticles; Zebrafish

Indexed keywords

CELL DEATH; GENE EXPRESSION; GENES; NANOPARTICLES; NEUROPHYSIOLOGY; NOREPINEPHRINE; TOXICITY;

BRAIN INJURY; MANUFACTURED NANOPARTICLES; MORPHOLOGICAL CHANGES; NEUROTRANSMITTERS; RECOGNITION MEMORY; SUBCHRONIC EXPOSURE; TIO; ZEBRAFISH;

TITANIUM DIOXIDE;

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOPAMINE; METABOTROPIC RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR ANTIBODY; NERVE GROWTH FACTOR; NITRIC OXIDE; NORADRENALIN; PROTEIN C FOS; PROTEIN C JUN; SEROTONIN; SYNAPTOPHYSIN; TITANIUM DIOXIDE NANOPARTICLE; 5 HYDROXYTRYPTOPHAN; NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; BRAIN DAMAGE; BRAIN LEVEL; BRAIN WEIGHT; CELL PROLIFERATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; ENZYME REPRESSION; EXPERIMENTAL FISH; FEMALE; GLIA CELL; HIPPOCAMPUS; LOCOMOTION; MALE; MAZE TEST; MEMORY DISORDER; MITOCHONDRION SWELLING; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SPATIAL MEMORY; TISSUE STRUCTURE; UPREGULATION; ZEBRA FISH; ANIMAL; ANIMAL BEHAVIOR; BRAIN; DRUG EFFECTS; GENE EXPRESSION; GLIA; MEMORY; METABOLISM; PATHOLOGY; PSYCHOLOGY; RECOGNITION; TOXICITY AND INTOXICATION; ULTRASTRUCTURE;

DANIO RERIO;

5-HYDROXYTRYPTOPHAN; ANIMALS; APOPTOSIS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; CELL PROLIFERATION; DOPAMINE; GENE EXPRESSION; MEMORY; NANOPARTICLES; NEUROGLIA; NEUROTOXICITY SYNDROMES; NITRIC OXIDE; NOREPINEPHRINE; RECOGNITION (PSYCHOLOGY); TITANIUM; ZEBRAFISH;

EID: 84953835742     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.22031     Document Type: Article

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