Vicia faba bioassay for environmental toxicity monitoring: A review

Chemosphere

Volumn 144, Issue , 2016, Pages 785-802

  Iqbal, Munawar ^a  

^a UNIVERSITY OF PESHAWAR   (Pakistan)

Author keywords

Bioassay; Broad bean; Contamination; Cytotoxicity; Ecotoxicology; Genotoxicity; Mutagenicity; Vicia faba; Wastewater

Indexed keywords

BIOASSAY; CELL PROLIFERATION; CHROMOSOMES; CONTAMINATION; CYTOTOXICITY; MUTAGENS; PETROLEUM INDUSTRY; SEWAGE; WASTEWATER;

BROAD BEAN; ECO-TOXICOLOGY; GENOTOXICITIES; MUTAGENICITY; VICIA FABA;

EFFLUENTS;

ACARICIDE; ALUMINUM CHLORIDE; ANTIMONY; ANTIMONY TRICHLORIDE; ARSENIC ACID; ARSENIC TRIOXIDE; CADMIUM; CADMIUM CHLORIDE; CHROMIUM; CHROMIUM CHLORIDE; COKE; DICHROMATE POTASSIUM; FUNGICIDE; HERBICIDE; HUMIC ACID; HYDROCARBON; INDUSTRIAL EFFLUENT; INORGANIC COMPOUND; INSECTICIDE; MUTAGENIC AGENT; NEODYMIUM; NICKEL CHLORIDE; OLIVE OIL; ORGANIC COMPOUND; PESTICIDE; PETROLEUM; PRASEODYMIUM; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG; UNINDEXED DRUG; POLLUTANT;

BIOASSAY; DNA; ECOTOXICOLOGY; ENVIRONMENTAL MONITORING; GENOTOXICITY; LEGUME; MUTAGENICITY; WASTEWATER;

ANAPHASE; ANEUPLOIDY; BIOASSAY; CELL KINETICS; CHROMATIN; CHROMOSOME ABERRATION; CHROMOSOME STRUCTURE; COKE PLANT WASTEWATER; CYTOGENETICS; CYTOTOXICITY; DISINFECTION; DNA DAMAGE; DNA FRAGMENTATION; DNA STRAND BREAKAGE; DNA SYNTHESIS INHIBITION; DROSOPHILA MELANOGASTER; ECOTOXICOLOGY; EFFLUENT TOXICITY; GAMMA RADIATION; GENOTOXICITY; LEATHER INDUSTRY; METAPHASE; MICRONUCLEUS; MITOSIS INDEX; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; NUCLEAR ABERRATION; PAPER INDUSTRY; PHYTOTOXICITY; POLYPLOIDY; PROPHASE; PULP MILL; REVIEW; ROOT GROWTH; SENSITIVITY ANALYSIS; SISTER CHROMATID EXCHANGE; SOIL POLLUTION; TELOPHASE; TEXTILE; TOXICITY TESTING; VICIA FABA; WASTE WATER; CYTOLOGY; DRUG EFFECTS; ENVIRONMENTAL MONITORING; GENETICS; HUMAN; POLLUTANT; PROCEDURES; TOXICITY;

EMBRYOPHYTA; VICIA FABA;

BIOLOGICAL ASSAY; ECOTOXICOLOGY; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; HUMANS; VICIA FABA;

EID: 84953790335     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2015.09.048     Document Type: Review

References (172)

1. Abdel Migid H.M., Azab Y.A., Ibrahim W.M. Use of plant genotoxicity bioassay for the evaluation of efficiency of algal biofilters in bioremediation of toxic industrial effluent. Ecotoxicol. Environ. Saf. 2007, 66:57-64.
2. Abu N.E., Ezeugwu S.C. Risk evaluation of industrial wastewater on plants using onion (Allium cepa L.) chromosome aberration assay. J. Trop. Agric. Food Environ. Ext. 2008, 7:242-248.
3. Abu N.E., Mba K. Mutagenecity testing of phamarceutical effluents on Allium cepa root tip meristems. J. Toxicol. Environ. Health Sci. 2011, 3:44-51.
4. Adam F., El-Ashry Z. Evaluation of genotoxicity of 4-n-nonylphenol using Vicia faba L. J. Biol. Sci. 2010, 10:368-372.
5. Aksoy Ã., Erbulucu T., Ãner S., Tekeli Ä.B. Phytotoxic and Genotoxic Effects of Water Samples Taken from the Eastern Channel of Kocaeli on Vicia faba and Zea mays 2012.
6. Al-Ahmadi M.S. Effect of gamma radiation on mitodepressive action of Aspergillus niger aflatoxin on Vicia faba root tip cells. J. Food Agric. Environ. 2015, 23:16-23.
7. Albertini R.J., Anderson D., Douglas G.R., Hagmar L., Hemminki K., Merlo F., Natarajan A., Norppa H., Shuker D.E.G., Tice R. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. Mutat. Res-Rev. Mutat. Res. 2000, 463:111-172.
8. Anwar F., Alghamdi S.S., Ammar M.H., Siddique K. An efficient in vitro regeneration protocol for faba bean (Vicia faba L.). J. Med. Plants Res. 2011, 5:6460-6467.
9. Arya S., Mukherjee A. Sensitivity of Allium cepa and Vicia faba towards cadmium toxicity. J. Soil Sci. Plant Nutr. 2014, 14:447-458.
10. Badr A. Cytogenetic activities of a triazine herbicide in root tips of Allium cepa and Vicia faba. Mutat. Res-Genet. Toxicol. 1983, 117:173-182.
11. Battersby N.S. The biodegradability and microbial toxicity testing of lubricants-some recommendations. Chemosphere 2000, 41:1011-1027.
12. Beraud E., Cotelle S., Leroy P., Ferard J.F. Genotoxic effects and induction of phytochelatins in the presence of cadmium in Vicia faba roots. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2007, 633:112-116.
13. Bianchi J., Espindola E.L.G., Marin-Morales M.A. Genotoxicity and mutagenicity of water samples from the Monjolinho River (Brazil) after receiving untreated effluents. Ecotoxicol. Environ. Saf. 2011, 74:826-833.
14. Bo J., Guangrong C., Ming L., Xingguo W. A study on the monitoring of soil pollution with the technique of Vicia faba micronucleus. Environ. Sci. 1992, 3. http://en.cnki.com.cn/Article_en/CJFDTOTAL-HJKZ199203020.htm.
15. Boccia P., Meconi C., Mecozzi M., Sturchio E. Molecular modifications induced by inorganic arsenic in Vicia faba investigated by FTIR, FTNIR spectroscopy and genotoxicity testing. J. Toxicol. Environ. Health Part A 2013, 76:281-290.
16. Boorman G.A. Drinking water disinfection byproducts: review and approach to toxicity evaluation. Environ. Health Perspect. 1999, 107:207-217.
17. Büyükkeskin T., Akinci Ş., Eroğlu A.E. Effects of humic acid on root development and nutrient uptake of Vicia faba L. (Broad Bean) seedlings grown under aluminum toxicity. Commun. Soil Sci. Plant Anal. 2015, 46:277-292.
18. Cavusoglu K., Yalcin E., Ergene A. The investigation of cytotoxic effects of refinery wastewater on root tip cells of Vicia faba L. J. Environ. Biol. 2010, 31:465-470.
19. Cavusoglu K., Yapar K., Kinalioglu K., Turkmen Z., Yalcin E. Protective role of Ginkgo biloba on petroleum wastewater-induced toxicity in Vicia faba L. (Fabaceae) root tip cells. J. Environ. Biol. 2010, 31:319-324.
20. Chandra R., Singh R. Decolourisation and detoxification of rayon grade pulp paper mill effluent by mixed bacterial culture isolated from pulp paper mill effluent polluted site. Biochem. Eng. J. 2012, 61:49-58.
21. Chandra S., Chauhan L., Pande P., Gupta S. Cytogenetic effects of leachates from tannery solid waste on the somatic cells of Vicia faba. Environ. Toxicol. 2004, 19:129-133.
22. Chen Y., Wang C., Wang Z., Huang S. Assessment of the contamination and genotoxicity of soil irrigated with wastewater. Plant Soil 2004, 261:189-196.
23. Chroust K., Kuglik P., Relichova J., Holoubek I., Caslavsky J., Veselska R., Ryskova M., Benedik J. Drosophila melanogaster, Vicia faba and Arabidopsis thaliana short-term bioassays in genotoxicity evaluation of air and soil samples from sites surrounding two industrial factories in the Czech Republic. Folia Biol. Praha 1997, 43:71-78.
24. Clemedson C., McFarlane-Abdulla E., Andersson M., Barile F., Calleja M., Chesné C., Clothier R., Cottin M., Curren R., Dierickx P. MEIC evaluation of acute systemic toxicity. Part II. In vitro results from 68 toxicity assays used to test the first 30 reference chemicals and a comparative cytotoxicity analysis. Altern. Lab. Anim. 1996, 24:273-310.
25. Coronel Olivares C. Assessment of the genotoxic potential of sediments contaminated with POPs and agricultural soils using Vicia faba micronucleus assay. Soil Sediment. Contam. Int. J. 2013, 22:288-300.
26. Cotelle S., Masfaraud J.-F., Férard J.-F. Assessment of the genotoxicity of contaminated soil with the Allium/Vicia-micronucleus and the Tradescantia-micronucleus assays. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:167-171.
27. Cotelle S., Testolin R.C., Foltête A.-S., Bossardi-Rissardi G., Silveira R.A., Radetski C.M. Genotoxicity potential of a new natural formicide. Environ. Sci. Pollut. Res. 2012, 19:628-635.
28. De Marco A., Boccardi P., De Simone C., Piccolo A., Raglione M., Testa A., Trinca S. Induction of micronuclei in Vicia faba root tips treated in different soils with the herbicide alachlor. Mutat. Res-Genet. Toxicol. 1990, 241:1-6.
29. De Marco A., De Simone C., D'Ambrosio C., Owczarek M. Buthionine sulfoximine prevents the reduction of the genotoxic activity of maleic hydrazide by soil humic substances in Vicia faba seedlings. Mutat. Res-Genet. Toxicol. Environ. Mutagen 1999, 438:89-95.
30. De Marco A., De Simone C., Raglione M., Lorenzoni P. Influence of soil characteristics on the clastogenic activity of maleic hydrazide in root tips of Vicia faba. Mutat. Res-Genet. Toxicol. 1995, 344:5-12.
31. De Marco A., De Simone C., Raglione M., Testa A., Trinca S. Importance of the type of soil for the induction of micronuclei and the growth of primary roots of Vicia faba treated with the herbicides atrazine, glyphosate and maleic hydrazide. Mutat. Res-Genet. Toxicol. 1992, 279:9-13.
32. De Marco A., Paglialunga S., Rizzoni M., Testa A., Trinca S. Induction of micronuclei in Vicia faba root tips treated with heavy metals (cadmium and chromium) in the presence of NTA. Mutat. Res-Genet. Toxicol. 1988, 206:311-315.
33. De Simone C., Piccolo A., De Marco A. Genotoxic effect induced by herbicides atrazine glyphosate in plants of Vicia faba grown in different soils. Sci. Total Environ. 1992, 123:233-240.
34. Degrassi F., Rizzoni M. Micronucleus test in Vicia faba root tips to detect mutagen damage in fresh-water pollution. Mutat. Res-Environ. Mutagen. Relat. Subj. 1982, 97:19-33.
35. deKergommeaux D.J., Grant W., Sandhu S. Clastogenic and physiological response of chromosomes to nine pesticides in the Vicia faba in vivo root tip assay system. Mutat. Res-Genet. Toxicol. 1983, 124:69-84.
36. Dhyèvre A., Foltête A.S., Aran D., Muller S., Cotelle S. Effects of soil pH on the Vicia-micronucleus genotoxicity assay. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2014, 774:17-21.
37. do Céu Silva M., Gaspar J., Silva I.D., Leão D., Rueff J. Induction of chromosomal aberrations by phenolic compounds: possible role of reactive oxygen species. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2003, 540:29-42.
38. Dong Y., Zhang J. Testing the genotoxicity of coking wastewater using Vicia faba and Hordeum vulgare bioassays. Ecotoxicol. Environ. Saf. 2010, 73:944-948.
39. Duan C.-Q., Hu B., Jiang X.-H., Wen C.-H., Wang Z., Wang Y.-X. Genotoxicity of water samples from Dianchi lake detected by the Vicia faba micronucleus test. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:121-125.
40. Duan C., Hu B., Guo T., Luo M., Xu X., Chang X., Wen C., Meng L., Yang L., Wang H. Changes of reliability and efficiency of micronucleus bioassay in Vicia faba after exposure to metal contamination for several generations. Environ. Exp. Bot. 2000, 44:83-92.
41. Duan P., Zhai T., Xu C., Ding J., Chen Y. A simple and effective method for detecting toxicity of chromium trioxide on Vicia faba. Euro. Food Res. Technol. 2013, 236:517-521.
42. Duquesnoy I., Champeau G.M., Evray G., Ledoigt G., Piquet-Pissaloux A. Enzymatic adaptations to arsenic-induced oxidative stress in Zea mays and genotoxic effect of arsenic in root tips of Vicia faba and Zea mays. Comptes Rendus Biol. 2010, 333:814-824.
43. EC Commission Regulation No 199/2006 of 19 December 2006 amending Regulation (EC) No 466/2001 setting maximum levels for certain contaminants in foodstuffs as regards dioxins and dioxin-like PCBs. Off. J. Eur. Union 2006, 5-24. L 364 (20/12/2006).
44. EC Commission Decision of 13 June 2007 concerning the non-inclusion of carbofuran in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance. Off. J. Eur. Union 2007, 30-31. L 156 (16/06/2007).
45. El-Shahaby O., Migid H.M.A., Soliman M., Mashaly I. Genotoxicity screening of industrial wastewater using the Allium chromosome aberration assay. Pak. J. Biol. Sci. 2003, 6:23-28.
46. El-Shazly H.H., El-Sheikh I.A. Arrest of mitotic cycle and induction of chromosomal aberrations by aflatoxin B2 in root cells of Vicia faba L. Cytologia 2000, 65:113-122.
47. El Hajjouji H., Pinelli E., Guiresse M., Merlina G., Revel J.C., Hafidi M. Assessment of the genotoxicity of olive mill waste water (OMWW) with the Vicia faba micronucleus test. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2007, 634:25-31.
48. Eleftheriou E.P., Michalopoulou V.A., Adamakis I.-D.S. Aberration of mitosis by hexavalent chromium in some Fabaceae members is mediated by species-specific microtubule disruption. Environ. Sci. Pollut. Res. 2015, 22:7590-7599.
49. Feng S., Mai B., Wei G., Wang X. Genotoxicity of the sediments collected from Pearl River in China and their polycyclic aromatic hydrocarbons (PAHs) and heavy metals. Environ. Monit. Assess. 2012, 184:5651-5661.
50. Feng S., Wang X., Wei G., Peng P., Yang Y., Cao Z. Leachates of municipal solid waste incineration bottom ash from Macao: heavy metal concentrations and genotoxicity. Chemosphere 2007, 67:1133-1137.
51. Feng Y., Li B., Guo X., Duan L., Cao J., Wang S., Cheng X., Xing C., Cui L. Toxicity evaluation on the effluent water from a sewage treatment plant in Zhengzhou City. J. Hyg. Res. 2011, 40:738-740.
52. Fernandes T.C.C., Mazzeo D.E.C., Marin-Morales M.A. Mechanism of micronuclei formation in polyploidizated cells of Allium cepa exposed to trifluralin herbicide. Pest. Biochem. Physiol. 2007, 88:252-259.
53. Flores-Maya S., Gómez-Arroyo S., Calderón-Segura M.E., Villalobos-Pietrini R., Waliszewski S.M., de la Cruz L.G. Promutagen activation of triazine herbicides metribuzin and ametryn through Vicia faba metabolism inducing sister chromatid exchanges in human lymphocytes in vitro and in V. faba root tip meristems. Toxicol. In Vitro 2005, 19:243-251.
54. Foltête A.-S., Masfaraud J.-F., Férard J.-F., Cotelle S. Is there a relationship between early genotoxicity and life-history traits in Vicia faba exposed to cadmium-spiked soils. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2012, 747:159-163.
55. Foltete A.S., Dhyère A., Férard J.F., Cotelle S. Improvement of Vicia-micronucleus test for assessment of soil quality: a proposal for international standardization. Chemosphere 2011, 85:1624-1629.
56. 2 nanocomposites on Vicia faba. Environ. Pollut. 2011, 159:2515-2522.
57. Giorgetti L., Talouizte H., Merzouki M., Caltavuturo L., Geri C., Frassinetti S. Genotoxicity evaluation of effluents from textile industries of the region Fez-Boulmane, Morocco: a case study. Ecotoxicol. Environ. Saf. 2011, 74:2275-2283.
58. Gómez-Arroyo S., Armienta M.A., CortÃs-Eslava J., Villalobos-Pietrini R. Sister chromatid exchanges in Vicia faba induced by arsenic-contaminated drinking water from Zimapan, Hidalgo, Mexico. Mutat. Res-Genet. Toxicol. Environ. Mutagen 1997, 394:1-7.
59. Gómez-Arroyo S., Baiza A.M., López G., Villalobos-Pietrini R. A comparative study of the cytogenetic effects of the insecticides heptachlor, malathion, and methyl parathion in Vicia faba. Rev. Int. Contam. Ambie 1985, 1:7-16.
60. Gowrishanker B., Vivekanandan O. In vivo studies of a crude extract of Phyllanthus amarus L. in modifying the genotoxicity induced in Vicia faba L. by tannery effluents. Mutat. Res-Genet. Toxicol. 1994, 322:185-192.
61. Grant W., Lee H., Logan D., Salamone M. The use of Tradescantia and Vicia faba bioassays for the in situ detection of mutagens in an aquatic environment. Mutat. Res-Fund. Mol. Mechan. Mutagen 1992, 270:53-64.
62. Grant W.F. The present status of higher plant bioassays for the detection of environmental mutagens. Mutat. Res-Fund. Mol. Mechan. Mutagen 1994, 310:175-185.
63. Grant W.F. Higher plant assays for the detection of chromosomal aberrations and gene mutations-a brief historical background on their use for screening and monitoring environmental chemicals. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:107-112.
64. Gupta A.K., Ahmad M. Assessment of cytotoxic and genotoxic potential of refinery waste effluent using plant, animal and bacterial systems. J. Hazard. Mater 2012, 201-202:92-99.
65. Gustavino B., Ceretti E., Zani C., Zerbini I., Rizzoni M., Monarca S., Feretti D. Influence of temperature on mutagenicity in plants exposed to surface disinfected drinking water. J. Water Resour. Prot. 2012, 4:638-647.
66. Helma C., Eckl P., Gottmann E., Kassie F., Rodinger W., Steinkellner H., Windpassinger C., Schulte-Hermann R., Knasmüller S. Genotoxic and ecotoxic effects of groundwaters and their relation to routinely measured chemical parameters. Environ. Sci. Technol. 1998, 32:1799-1805.
67. Hua N., Chong Z. Detection of water pollution in Yezhi Lake by Vicia micronucleus technology. Eng. J. Wuhan. Univ. 2011, 2. 015.
68. Hui-Lan Y., Xin-Feng L., Zi-Qiang M. Micronucleus and anaphase aberrations in vicia faba root tips induced by the derivatives of sulfur dioxide. Bull. Bot. Res. 2003, 23:308-311.
69. Iqbal M., Bhatti I.A. Re-utilization option of industrial wastewater treated by advanced oxidation process. Pak. J. Agric. Sci. 2014, 51:1141-1147.
70. 2 treatment of a nonylphenol ethoxylates: degradation, cytotoxicity, and mutagenicity evaluation. J. Hazard. Mater. 2015, 299:351-360.
71. Iqbal M., Bhatti I.A., Zia-ur-Rehman M., Bhatti H.N., Shahid M. Efficiency of advanced oxidation processes for detoxification of industrial effluents. Asian J. Chem. 2014, 26:4291-4296.
72. Iqbal M., Nisar J. Cytotoxicity and mutagenicity evaluation of gamma radiation and hydrogen peroxide treated textile effluents using bioassays. J. Environ. Chem. Eng. 2015, 3:1912-1917.
73. ISO 29200-Soil Quality - Assessment of Genotoxic Effects on Higher Plants - Vicia faba Micronucleus Test 2013, International Organization for Standardization, Genève.
74. Jain K., Singh J., Chauhan L., Murthy R., Gupta S. Modulation of flyash-induced genotoxicity in Vicia faba by vermicomposting. Ecotoxicol. Environ. Saf. 2004, 59:89-94.
75. Jha A.M., Singh A.C. Clastogenicity of lanthanides-induction of micronuclei in root tips of Vicia faba. Mutat. Res-Genet. Toxicol. 1994, 322:169-172.
76. Ji Q., Chen Y. Vicia faba root tip micronucleus test on the mutagenicity of water-soluble contents of cigarette smoke. Mutat. Res-Environ. Mutagen. Relat. Subj. 1996, 359:1-6.
77. Ji Q., Yang H., Zhang X. Vicia root-micronuclei assays on the clastogenicity of water samples from the Kui River near Xuzhou city, People's Republic of China. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:133-135.
78. Jie-Qiang L., Qin-Gling W., Nian-Ci L., Yu-Yuan W. Study on the detection of water pollution from the seven sewage streams in Guangzhou City using Vicia faba root-tip cells micronucleus testing. J. S. China Normal Univ. (Nat. Sci. Ed.) 2006, 2. http://en.cnki.com.cn/Article_en/CJFDTotal-DNYX201001029.htm.
79. Jing-Jing Y. Study on organic wastewater monitoring of laboratory using mcn test of Vicia faba root tips. J. Anhui Agric. Sci. 2011, 17. http://en.cnki.com.cn/Article_en/CJFDTotal-AHNY201117118.htm.
80. Juárez-Santacruz L., García-Nieto E., Costilla-Salazar R., García-Gallegos E., Coronel-Olivares C., Gómez-Camarillo M., Gaytán-Oyarzún J. Assessment of the genotoxic potential of sediments contaminated with POPs and agricultural soils using Vicia faba micronucleus assay. Soil Sediment. Contam. Int. J. 2013, 22:288-300.
81. Jun-Hui Z., Hang M. Eco-toxicity and metal contamination of paddy soil in an e-wastes recycling area. J. Hazard. Mater 2009, 165:744-750.
82. Kaiquan L., Zhengwu W., Xiaodong S., Chunfang L., Rongcheng Z. Study on wastewater pollution of metal refinery with micronucleus test method. J. Qujing Normal Univ. 2007, 6. http://en.cnki.com.cn/Article_en/CJFDTOTAL-QJSZ200706007.htm.
83. Kanaya N., Gill B., Grover I., Murin A., Osiecka R., Sandhu S., Andersson H. Vicia faba chromosomal aberration assay. Mutat. Res-Fund. Mol. Mechan. Mutagen 1994, 310:231-247.
84. Khadra A., Pinelli E., Lacroix M., Bousquet-Mélou A., Hamdi H., Merlina G., Guiresse M., Hafidi M. Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test. Ecotoxicol. Environ. Saf. 2012, 76:187-192.
85. Kihlman B. Root tips of Vicia faba for the study of the induction of chromosomal aberrations. Mutat. Res-Environ. Mutagen. Relat. Subj. 1975, 31:401-412.
86. Knasmüller S., Gottmann E., Steinkellner H., Fomin A., Pickl C., Paschke A., Gãd R., Kundi M. Detection of genotoxic effects of heavy metal contaminated soils with plant bioassays. Mutat. Res-Genet. Toxicol. Environ. Mutagen 1998, 420:37-48.
87. Kong Z., Zang Y., Wu Q. Monitoring the genotoxicity of Lake Taihu, using two kinds of micronucleus tests. Environ. Pollut. 1998, 99:279-283.
88. Kontek R., Osiecka R., Kontek B. Clastogenic and mitodepressive effects of the insecticide dichlorvos on root meristems of Vicia faba. J. Appl. Genet. 2007, 48:359-361.
89. Kristen U. Use of higher plants as screens for toxicity assessment. Toxicol. In Vitro 1997, 11:181-191.
90. Kwasniewska J., Nałecz-Jawecki G., Skrzypczak A., Płaza G., Matejczyk M. An assessment of the genotoxic effects of landfill leachates using bacterial and plant tests. Ecotoxicol. Environ. Saf. 2012, 75:55-62.
91. Lan-ping W. Detection on the water qualities of main rivers of yancheng city by broad bean root-tip cell micronucleus technique. J. Anhui Agric. Sci. 07, 2009, http://en.cnki.com.cn/Article_en/CJFDTOTAL-AHNY200907134.htm.
92. Leme D.M., Marin-Morales M.A. Allium cepa test in environmental monitoring: a review on its application. Mutat. Res-Rev. Mutat. Res. 2009, 682:71-81.
93. Li Y., Hu Y., Cai M., Qiao L., Li J. Study on water pollution of Sanhai in Beijing with micronucleus test method. Chin. J. Ecol. 2005, 9. http://en.cnki.com.cn/Article_en/CJFDTOTAL-STXZ200509025.htm.
94. Lin A., Zhang X., Zhu Y.G., Zhao F.J. Arsenate-induced toxicity: effects on antioxidative enzymes and DNA damage in Vicia faba. Environ. Toxicol. Chem. 2008, 27:413-419.
95. Liu J., Yi H.L. Cytogenetic Damage Induced by Sulfur Dioxide in Vicia faba Root and Leaf Meristematic Cells 2007, http://en.cnki.com.cn/Article_en/CJFDTOTAL-MBZW200706021.htm.
96. Liu R., Qi Y., Lv M. Study on detecting the genetic toxicity of synthesis ammonia industrial waste by Vicia faba root-tip cell micronucleus technique. Biotechnology 2007, 01. http://en.cnki.com.cn/Article_en/CJFDTOTAL-SWJS200701020.htm.
97. Liu T., Zhu L., Wang J., Wang J., Xie H. The genotoxic and cytotoxic effects of 1-butyl-3-methylimidazolium chloride in soil on Vicia faba seedlings. J. Hazard. Mater. 2015, 285:27-36.
98. Liu W., Zhou Q., Li P., Sun T., Tai P., Xu H., Zhang C., Zhang H. Effects of chlorobenzene stress on seedling growth and cell division of Vicia faba. J. Appl. Ecol. 2003, 14:585-588.
99. Liu Y., Lu Y. Genotoxicity of coke plant wastewater on root tips of Vicia faba. International Conference on Energy and Environment Technology 2009, vol. 2:593-596.
100. Ma J., Guo D., Su W., Wang D., Guo C. Evaluation of phytotoxicity and genotoxicity of nitrobenzene with A battery of Vicia faba assay system. Environ. Toxicol. Chem. 2013, 32:1426-1432.
101. Ma J., Shen J., Liu Q., Fang F., Cai H., Guo C. Risk assessment of petroleum-contaminated soil using soil enzyme activities and genotoxicity to Vicia faba. Ecotoxicology 2014, 23:665-673.
102. Ma L., Zhang Y., Bu N., Wang S. Alleviation effect of alginate-derived oligosaccharides on Vicia faba root tip cells damaged by cadmium. Bull. Environ. Contamin. Toxicol. 2010, 84:161-164.
103. Ma T.H., Xu Z., Xu C., McConnell H., Valtierra Rabago E., Adriana Arreola G., Zhang H. The improved Allium/Vicia root tip micronucleus assay for clastogenicity of environmental pollutants. Mutat. Res-Environ. Mutagen. Relat. Subj. 1995, 334:185-195.
104. Ma X., Wang X., Liu Y. Cytotoxicity and genotoxicity evaluation of urban surface waters using freshwater. Mutat. Res-Rev. Mutat. Res. 2012, 410:237-243.
105. Manzo S., Picione F., Rocco A., Carotenuto R., Maisto G. Urban and agricultural soil ecotoxicity and heavy metal contamination. Fresen. Environ. Bull. 2010, 19:1749-1755.
106. Marcato-Romain C.-E., Guiresse M., Cecchi M., Cotelle S., Pinelli E. New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. Chemosphere 2009, 77:345-350.
107. Marcato-Romain C., Pinelli E., Pourrut B., Silvestre J., Guiresse M. Assessment of the genotoxicity of Cu and Zn in raw and anaerobically digested slurry with the Vicia faba micronucleus test. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2009, 672:113-118.
108. Mecozzi M., Sturchio E. Effects of essential oil treatments on the secondary protein structure of Vicia faba: a mid-infrared spectroscopic study supported by two-dimensional correlation analysis. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2015, 137:90-98.
109. Melnick R.L., Dunnick J.K., Sandler D.P., Elwell M.R., Barrett J.C. Trihalomethanes and other environmental factors that contribute to colorectal cancer. Environ. Health Perspect. 1994, 102:586-588.
110. Miao M., Fu R., Yang D., Zheng L. Vicia root micronucleus assay on the clastogenicity of water samples from the Xiaoqing River in Shandong Province of the People's Republic of China. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:143-145.
111. Minissi S., Caccese D., Passafiume F., Grella A., Ciccotti E., Rizzoni M. Mutagenicity (micronucleus test in Vicia faba root tips), polycyclic aromatic hydrocarbons and heavy metal content of sediments collected in Tiber river and its tributaries within the urban area of Rome. Mutat. Res-Genet. Toxicol. Environ. Mutagen 1998, 420:77-84.
112. Minissi S., Lombi E. Heavy metal content and mutagenic activity, evaluated by Vicia faba micronucleus test, of Tiber river sediments. Mutat. Res-Genet. Toxicol. Environ. Mutagen 1997, 393:17-21.
113. 137Cs radiation using Vicia-micronucleus, Tradescantia-micronucleus and Tradescantia-stamen-hair mutation bioassays. J. Environ. Radioact. 2005, 81:143-153.
114. Monarca S., Feretti D., Zani C., Rizzoni M., Casarella S., Gustavino B. Genotoxicity of drinking water disinfectants in plant bioassays. Environ. Mol. Mutagen 2005, 46:96-103.
115. Monarca S., Rizzoni M., Gustavino B., Zani C., Alberti A., Feretti D., Zerbini I. Genotoxicity of surface water treated with different disinfectants using in situ plant tests. Environ. Mol. Mutagen 2003, 41:353-359.
116. Monarca S., Zani C., Richardson S.D., Thruston A.D., Moretti M., Feretti D., Villarini M. A new approach to evaluating the toxicity and genotoxicity of disinfected drinking water. Water Res. 2004, 38:3809-3819.
117. Ohe T., Watanabe T., Wakabayashi K. Mutagens in surface waters: a review. Mutat. Res-Rev. Mutat. Res. 2004, 567:109-149.
118. Pandey R. Cytotoxic effects of pesticides in somatic cells of Vicia faba L. Cytol. Genet. 2008, 42:373-377.
119. Pang H., Lu Y., Lu H. Micronuclei in root-tip cells of Vicia faba caused by the water from Xuanwu Lake and Jingchuan River. Nanjing shida xuebao 1996, 19:52-55.
120. Parng C. In vivo zebrafish assays for toxicity testing. Curr. Opin. Drug Disc. Dev. 2005, 8:100-106.
121. Patlolla A.K., Berry A., May L.B., Tchounwou P.B. Genotoxicity of silver nanoparticles in Vicia faba: a pilot study on the environmental monitoring of nanoparticles. Int. J. Environ. Res. Publ. Health 2012, 9:1649-1662.
122. Poschenrieder C., Gunsé B., Barceló J. Influence of cadmium on water relations, stomatal resistance, and abscisic acid content in expanding bean leaves. Plant Physiol. 1989, 90:1365-1371.
123. Pourrut B., Jean S., Silvestre J., Pinelli E. Lead-induced DNA damage in Vicia faba root cells: potential involvement of oxidative stress. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2011, 726:123-128.
124. Qian X.-w. Mutagenic effects of chromium trioxide on root tip cells of Vicia faba. J. Zhejiang Univ. Sci. 2004, 5:1570-1576.
125. Qian X.-w., Luo W.-h., Zheng O.-x. Joint effects of microwave and chromium trioxide on root tip cells of Vicia faba. J. Zhejiang Univ. Sci. B 2006, 7:221-227.
126. 3 on Vicia faba root tip cells in vivo. Yi Chuan 2002, 24:305-309.
127. Qian X.W. Teratogenic effect of copper acetic acid on Vicia faba root tip cells. Chin. J. Coll. Biol. 2005, 3. http://en.cnki.com.cn/Article_en/CJFDTOTAL-XBZZ200503025.htm.
128. Quanzhan C., Bianjiang Z. The study on water pollution of inner Qinhuai river using micronudeus Vicia faba root tip cells test technique. J. Nanjing Teach. Coll. 2003, 4. http://en.cnki.com.cn/Article_en/CJFDTOTAL-SFZK200304005.htm.
129. Qureshi K., Ahmad M.Z., Bhatti I.A., Iqbal M., Khan A. Cytotoxicity reduction of wastewater treated by advanced oxidation process. Chem. Int. 2015, 1:53-59.
130. Radetski C., Ferrari B., Cotelle S., Masfaraud J.F., Ferard J. Evaluation of the genotoxic, mutagenic and oxidant stress potentials of municipal solid waste incinerator bottom ash leachates. Sci. total Environ. 2004, 333:209-216.
131. Raoof K.A., Siddiqui M. Allelotoxic effect of parthenin on cytomorphology of broad bean (Vicia faba L.). J. Saudi Soc. Agric. Sci. 2013, 12:143-146.
132. Richardson S.D., DeMarini D.M., Kogevinas M., Fernandez P., Marco E., Lourencetti C., Ballesté C., Heederik D., Meliefste K., McKague A.B. What's in the pool? A comprehensive identification of disinfection by-products and assessment of mutagenicity of chlorinated and brominated swimming pool water. Environ. Health Perspect. 2010, 118:1523-1530.
133. Rizzo L. Bioassays as a tool for evaluating advanced oxidation processes in water and wastewater treatment. Water Res. 2011, 45:4311-4340.
134. Rizzoni M., Vitagliano E., Marconi M., Sottili A., Gustavino B. Micronucleus induction by low doses of X-rays in Vicia faba root tips. Mutat. Res-Fund. Mol. Mechan. Mutagen 1987, 176:205-209.
135. Rosa E.V.C., Simionatto E.L., de Souza Sierra M.M., Bertoli S.L., Radetski C.M. Toxicity-based criteria for the evaluation of textile wastewater treatment efficiency. Environ. Toxicol. Chem. 2001, 20:839-845.
136. Rosa E.V.C., Valgas C., Souza-Sierra M.M., Corrěa A.X., Radetski C.M. Biomass growth, micronucleus induction, and antioxidant stress enzyme responses in Vicia faba exposed to cadmium in solution. Environ. Toxicol. Chem. 2003, 22:645-649.
137. Ruiz-Suárez N., Boada L.D., Henríquez-Hernández L.A., González-Moreo F., Suárez-Pérez A., Camacho M., Zumbado M., Almeida-González M., del Mar Travieso-Aja M., Luzardo O.P. Continued implication of the banned pesticides carbofuran and aldicarb in the poisoning of domestic and wild animals of the Canary Islands (Spain). Sci. Total Environ. 2015, 505:1093-1099.
138. Russel P.J. Chromosomal mutation. Genetics 2002, 595-621. Pearson Education Inc., San Francisco. B. Cummings (Ed.).
139. Sandhu S.S., Waters M.D., Simmon V.F., Mortelmans K.E., Mitchell A.D., Jorgenson T., Jones D., Valencia R., Stack F. Evaluation of the genotoxic potential of certain pesticides used in Pakistan. Basic life Sci. 1985, 34:185-219.
140. Sang N., Li G. Genotoxicity of municipal landfill leachate on root tips of Vicia faba. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2004, 560:159-165.
141. Shahid M., Dumat C., Pourrut B., Abbas G., Shahid N., Pinelli E. Role of metal speciation in lead-induced oxidative stress to Vicia faba roots. Russ. J. Plant Physiol. 2015, 62:448-454.
142. Shahid M., Dumat C., Silvestre J., Pinelli E. Effect of fulvic acids on lead-induced oxidative stress to metal sensitive Vicia faba L. plant. Biol. Fertil. Soil 2012, 48:689-697.
143. Shahid M., Pinelli E., Pourrut B., Silvestre J., Dumat C. Lead-induced genotoxicity to Vicia faba L. roots in relation with metal cell uptake and initial speciation. Ecotoxicol. Environ. Saf. 2011, 74:78-84.
144. Shahin S., El-Amoodi K.H. Induction of numerical chromosomal aberrations during DNA synthesis using the fungicides nimrod and rubigan-4 in root tips of Vicia faba L. Mutat. Res-Genet. Toxicol. 1991, 261:169-176.
145. Shu-mei L. A study on the detection of water pollution from Yinghe River in Zhoukou City by using micronucleus in Vicia faba root-tip test technique. J. Henan Normal Univ. (Nat. Sci.) 2001, 2. http://en.cnki.com.cn/Article_en/CJFDTOTAL-HNSX200102032.htm.
146. Sik L., Acar O., Aki C. Genotoxic effects of industrial wastewater on Allium cepa L. Afr. J. Biotechnol. 2009, 8:1919-1923.
147. Silva V.C., Almeida S.M., Resgalla C., Masfaraud J.-F., Cotelle S., Radetski C.M. Arsenate (As V) in water: quantitative sensitivity relationships among biomarker, ecotoxicity and genotoxicity endpoints. Ecotoxicol. Environ. Saf. 2013, 92:174-179.
148. Soliman M.I., Ghoneam G.T. The mutagenic potentialities of some herbicides using Vicia faba as a biological system. Biotechnol 2004, 3:140-154.
149. Song Y., Gong P., Wilke B., Zhang W., Song X., Sun T., Ackland M. Genotoxicity assessment of soils from wastewater irrigation areas and bioremediation sites using the Vicia faba root tip micronucleus assay. J. Environ. Monit. 2007, 9:182-186.
150. Song Y., Wilke B.M., Song X., Gong P., Zhou Q., Yang G. Polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and heavy metals (HMs) as well as their genotoxicity in soil after long-term wastewater irrigation. Chemosphere 2006, 65:1859-1868.
151. Souguir D., Ferjani E., Ledoigt G., Goupil P. Exposure of Vicia faba and Pisum sativum to copper-induced genotoxicity. Protoplasma 2008, 233:203-207.
152. Souguir D., Ferjani E., Ledoigt G., Goupil P. Sequential effects of cadmium on genotoxicity and lipoperoxidation in Vicia faba roots. Ecotoxicology 2011, 20:329-336.
153. Srivastava K., Mishra K.K. Cytogenetic effects of commercially formulated atrazine on the somatic cells of Allium cepa and Vicia faba. Pest. Biochem. Physiol. 2009, 93:8-12.
154. Sta C., Ledoigt G., Ferjani E., Goupil P. Exposure of Vicia faba to sulcotrione pesticide induced genotoxicity. Pest. Biochem. Physiol. 2012, 103:9-14.
155. Steinkellner H., Munâ-Sik K., Helma C., Ecker S., Ma T.H., Horak O., Kundi M., Knasmueller S. Genotoxic effects of heavy metals: comparative investigation with plant bioassays. Environ. Mol. Mutagen 1998, 31:183-191.
156. Sturchio E., Napolitano P., Beni C., Mecozzi M. Evaluation of arsenic effects in vicia faba by FTIR and FTNIR spectroscopy. Glob. Nest J. 2012, 14:86-92.
157. Ünyayar S., Çelik A., Çekiç F.Ö., Gözel A. Cadmium-induced genotoxicity, cytotoxicity and lipid peroxidation in Allium sativum and Vicia faba. Mutagen 2006, 21:77-81.
158. Villalobos Pietrini R., Flores Mãrquez A.R., Gãmez Arroyo S. Cytogenetic effects in Vicia faba of the polluted water from rivers of the Tlaxcala hydrological system, Mexico. Rev. Int. Contam. Ambie 2012, 10:83-88.
159. Wang C.R., Tian Y., Wang X.R., Yu H.X., Lu X.W., Wang C., Wang H. Hormesis effects and implicative application in assessment of lead-contaminated soils in roots of Vicia faba seedlings. Chemosphere 2010, 80:965-971.
160. Wang H. Clastogenicity of chromium contaminated soil samples evaluated by Vicia root-micronucleus assay. Mutat. Res-Fund. Mol. Mechan. Mutagen 1999, 426:147-149.
161. Wilsnack R., Meyer F., Smith J. Human cell culture toxicity testing of medical devices and correlation to animal tests. Artif. Cell. Blood Substit. Biotechnol. 1973, 1:543-562.
162. Wiszniowski J., Sindera P., Duquesnoy I., Surmacz-Gãrska J. Effect of biological treatment on genotoxicity of industrial wastewaters: root tips Vicia faba assay. Architecture 2009, 2:137-143.
163. Wu L., Yi H., Yi M. Assessment of arsenic toxicity using Allium/Vicia root tip micronucleus assays. J. Hazard. Mater. 2010, 176:952-956.
164. Xiao-Qian C. Genotoxicity study of water sample from water supply and drainage system using micronucleus in Vicia faba root tip cells. Carcinog. Teratog. Mutagen 2000, 4. http://en.cnki.com.cn/Article_en/CJFDTOTAL-ABJB200004006.htm.
165. Yadav S. Heavy metals toxicity in plants: an overview on the role of glutathione and phytochelatins in heavy metal stress tolerance of plants. S. Afr. J. Bot. 2010, 76:167-179.
166. Yi H., Meng Z. Genotoxicity of hydrated sulfur dioxide on root tips of Allium sativum and Vicia faba. Mutat. Res-Genet. Toxicol. Environ. Mutagen 2003, 537:109-114.
167. Yi M., Yi H., Li H., Wu L. Aluminum induces chromosome aberrations, micronuclei, and cell cycle dysfunction in root cells of Vicia faba. Environ. Toxicol. 2010, 25:124-129.
168. Zhang H., Cheng X., Ba Y. Mutagenicity of water from Yangling-Xingping section of Weihe river and wastewater from paper mills along the river. J. Environ. Health 2004, 21:96-98.
169. Zhang H., Zhang S., Meng Q., Zou J., Jiang W., Liu D. Effects of aluminum on nucleoli in root tip cells, root growth and the antioxidant defense system in Vicia faba L. Acta Biol. Cracovien. Ser. Bot. 2009, 51:99-106.
170. Zhen-Ling P., Er-Qin Z., Rui-Qing D. Study on the monitoring of the water quality in root-tip of Vicia faba cell micronucleus technique. North. Hortic. 08, 2008, http://en.cnki.com.cn/Article_en/CJFDTotal-BFYY200808003.htm.
171. ZhiGang Y., QiaoGu F. Utilization of micronucleus test technique in Vicia faba root tips to evaluate the genetic toxicity of three heavy metal ions. J. Fujian Agric. For. Univ. (Nat. Sci. Ed.) 2009, 38:396-399.
172. Zhong Y., Feng S., Luo Y., Zhang G., Kong Z. Evaluating the genotoxicity of surface water of Yangzhong city using the Vicia faba micronucleus test and the comet assay. Bull. Environ. Contam. Toxicol. 2001, 67:217-224.