Synthesis and physicochemical, in vitro and in vivo evaluation of an anisotropic, nanocrystalline hydroxyapatite bisque scaffold with parallel-aligned pores mimicking the microstructure of cortical bone

Journal of Tissue Engineering and Regenerative Medicine

Volumn 9, Issue 12, 2015, Pages E152-E166

  Despang, F ^a,b   Bernhardt, A ^a,b   Lode, A ^a,b   Dittrich, R ^c   Hanke, T ^b   Shenoy, S J ^d   Mani, S ^d   John, A ^d   Gelinsky, M ^a,b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c TU BERGAKADEMIE FREIBERG   (Germany)

^d SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES AND TECHNOLOGY   (India)

Author keywords

Anisotropic scaffold; Biomimetic material; Bone tissue engineering; Cytocompatibility; Femoral defect; Human mesenchymal stem cells; Ionotropic gelation of alginate; Nanocrystalline apatite

Indexed keywords

ANISOTROPY; APATITE; BIOCERAMICS; BIOCOMPATIBILITY; BIOMIMETICS; BONE; CELL CULTURE; CELL ENGINEERING; COMPRESSIVE STRENGTH; MICROSTRUCTURE; NANOCRYSTALS; SCAFFOLDS (BIOLOGY); SINTERING; STEM CELLS; TEMPERATURE;

ANISOTROPIC SCAFFOLDS; BONE TISSUE ENGINEERING; CORTICAL BONE; CYTOCOMPATIBILITY; FEMORAL DEFECTS; HUMAN MESENCHYMAL STEM CELLS; IN-VITRO; IONOTROPIC GELATION OF ALGINATE; NANOCRYSTALLINE APATITES; TRABECULAR BONES;

HYDROXYAPATITE;

ALGINIC ACID; ANISOTROPIC HYDROXYAPATITE BISQUE; HYDROXYAPATITE; MOLECULAR SCAFFOLD; UNCLASSIFIED DRUG; BONE PROSTHESIS; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; BIOCHEMICAL COMPOSITION; BIOCOMPATIBILITY; BONE DEFECT; BONE STRUCTURE; CELL ADHESION; CELL DIFFERENTIATION; CELL FUSION; CELL PROLIFERATION; CERAMICS; COMPRESSIVE STRENGTH; CONTROLLED STUDY; CORTICAL BONE; DISSOLUTION; HIGH TEMPERATURE; HISTOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW TEMPERATURE; MESENCHYMAL STEM CELL; MONOCYTE; NANOANALYSIS; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCLAST ACTIVITY; OSTEOCLASTOGENESIS; PHYSICAL CHEMISTRY; POROSITY; PRIORITY JOURNAL; RABBIT MODEL; STRUCTURE ANALYSIS; SURFACE AREA; SYNTHESIS; TRABECULAR BONE; ANIMAL; BONE DEVELOPMENT; BONE PROSTHESIS; CHEMISTRY; DRUG EFFECTS; FEMALE; FEMUR; MALE; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; PHARMACOLOGY; RABBIT; TISSUE SCAFFOLD;

ANIMALS; ANISOTROPY; BONE SUBSTITUTES; CELL DIFFERENTIATION; DURAPATITE; FEMALE; FEMUR; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; NANOPARTICLES; OSTEOBLASTS; OSTEOGENESIS; POROSITY; RABBITS; TISSUE SCAFFOLDS;

EID: 84953736332     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1729     Document Type: Article

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