Porous hydroxyapatite/gelatine scaffolds with ice-designed channel-like porosity for biomedical applications

Acta Biomaterialia

Volumn 4, Issue 6, 2008, Pages 1620-1626

  Landi, Elena ^a   Valentini, Federica ^a   Tampieri, Anna ^a  

^a INSTITUTE OF SCIENCE AND TECHNOLOGY FOR CERAMICS   (Italy)

Author keywords

Freeze casting; Gelatine; Hydroxyapatite; Mechanical properties; Porous scaffold

Indexed keywords

BODY FLUIDS; ICE; MEDICAL APPLICATIONS; POROSITY; SINTERING;

BIOMEDICAL APPLICATIONS; CRYOGENIC PROCESS; FREEZE CASTING; FREEZE DRYING; GELATIN; LAMELLAR MORPHOLOGY; POROUS HYDROXYAPATITE; POROUS SCAFFOLD; PROCESS PARAMETERS; SYNTHETIC BODY FLUIDS;

HYDROXYAPATITE;

GELATIN; HYDROXYAPATITE; ICE;

ARTICLE; BIOMEDICINE; BODY FLUID; BONE PROSTHESIS; CHANNEL GATING; COMPRESSIVE STRENGTH; CONTROLLED STUDY; CROSS LINKING; FREEZE DRYING; FREEZING; HYBRID; POROSITY; PRIORITY JOURNAL; THICKNESS; YOUNG MODULUS;

EID: 53649109667     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2008.05.023     Document Type: Article

References (16)

1. Studart A.R., Gonzenbach U.T., Tervoort E., and Gauckler L.J. Processing routes to macroporous ceramics: a review. J. Am. Ceram. Soc 89 (2006) 1771-1789
2. Jun I.K., Song J.H., Choi W.Y., Koh Y.H., and Kim H.E. Porous hydroxyapatite scaffolds coated with bioactive apatite-Wollastonite glass-ceramics. J. Am. Ceram. Soc 90 (2007) 2703-2708
3. Sepulveda P., Bressiani A.H., Bressiani J.C., Meseguer L., and König Jr. B. In vivo evaluation of hydroxyapatite foams. Mat. Res. 5 (2002) 253-256
4. Tadic D., Beckmann F., Schwarz K., and Epple M. A novel method to produce hydroxyapatite objects with interconnecting porosity that avoids sintering. Biomaterials 25 (2004) 3335-3340
5. Fukasawa T., Ando M., Ohji T., and Kanzaki S. Synthesis of porous ceramics with complex pore structure by freeze-dry processing. J.Am.Ceram.Soc 84 (2001) 230-232
6. Deville S., Saiz E., and Tomsia A.P. Freeze casting of hydroxyapatite scaffolds for bone tissue engineering. Biomaterials 27 (2006) 5480-5489
7. Tampieri A., Celotti G., Landi E., Montevecchi M., Roveri N., and Bigi A. Porous phosphate gelatin composite as bone graft with drug delivery function. J. Mater. Sci. Mat Med 14 (2003) 623-627
8. Liu B, Lin P, ShenY, Dong Y. Porous bioceramics reinforced by coating gelatine. J Mater Sci: Mater Med. DOI 10.1007/s10856-007-3216-1.
9. Yao C.H., Liu B.S., Hsu S.H., Chen Y.S., and Tsai C.C. Biocompatibility and biodegradation of a bone composite containing tricalcium phosphate and genipine cross-linked gelatine. J Biomed Mater Res. 69A (2004) 709-717
10. Dubruel P., Unger R., Van Vlierberghe S., Cnudde V., Jacobs P.J.S., and Schacht E. Porous gelatin hydrogels: 2. In vitro cell interaction study. Biomacromulecules 8 (2007) 338-344
11. Bigi A., Cojazzi G., Panzavolta S., Roveri N., and Rubini K. Stabilization of gelatin film by cross-linking with genipine. Biomaterials 23 (2002) 4827-4832
12. Sierpowska J., Hakulinen M.A., Toyras J., Day J.S., Weinans H., and Jurvelin J.S. Prediction of mechanical properties of human trabecular bone by electrical measurements. Physiological Measurement 26 (2005) 119-131
13. Ding M. Age variation in the properties of human tibial trabecular bone and cartilage. Acta Orthop. Scand. 292 (2000) 1-45
14. Keaveny T.M. Cancellous bone. In: Black J., and Hastings G. (Eds). Handbook of Biomaterial Properties (1998), Chapman & Hall, London
15. Kozlov P.V. The structure and properties of solid gelatin and the principles of their modification. Polymer 24 (1983) 651-666
16. Morgan E.F., and Keaveny T.M. Dependence of yield strain of human trabecular bone on anatomic site. Journal of Biomechanics 34 (2001) 569-577