Immunolocalization of CD34 in nasal polyposis: Effect of topical corticosteroids

American Journal of Respiratory Cell and Molecular Biology

Volumn 20, Issue 3, 1999, Pages 388-397

  Kim, Young Ki ^b   Uno, Masashi ^b   Hamilos, Daniel L ^b   Beck, Lisa ^b   Bochner, Bruce ^b   Schleimer, Robert ^b   Denburg, Judah A ^a  

^a MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BUDESONIDE; CD34 ANTIGEN; CORTICOSTEROID; GLUCOCORTICOID; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CHEMISTRY; CYTOLOGY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; MIDDLE AGED; NOSE POLYP; PATHOLOGY; TOPICAL DRUG ADMINISTRATION; VASCULAR ENDOTHELIUM;

ADMINISTRATION, TOPICAL; ADRENAL CORTEX HORMONES; ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD34; BUDESONIDE; ENDOTHELIUM, VASCULAR; FEMALE; GLUCOCORTICOIDS; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NASAL POLYPS; VON WILLEBRAND FACTOR;

EID: 0033094834     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.20.3.3060     Document Type: Article

References (41)

1. Kanai, N., J. Denburg, M. Jordana, and J. Dolovich. 1994. Nasal polyp inflammation: effect of topical nasal steroid. Am. J. Respir. Crit. Care Med. 150:1094-1100.
2. Otsuka, H., J. Dolovich, A. D. Befus, J. Bienenstock, and J. A. Denburg. 1986. Peripheral blood basophils, basophil progenitors, and nasal metachromatic cells in allergic rhinitis. Am. Rev. Respir. Dis. 133:757-762.
3. Denburg, J. A., S. Telizyn, A. Belda, J. Dolovich, and J. Bienenstock. 1985. Increased numbers of circulating basophil progenitors in atopic patients. J. Allergy Clin. Immunol. 76:466-472.
4. Gibson, P. G., P. J. Manning, P. M. O'Byrne, A. Girgis-Gabardo, J. Dolovich, J. A. Denburg, and F. E. Hargreave. 1991. Allergen-induced asthmatic responses: relationship between increases in airway responsiveness and increases in circulating eosinophils, basophils, and their progenitors. Am. Rev. Respir. Dis. 143:331-335.
5. Wood, L. J., M. D. Inman, R. M. Watson, R. Foley, J. A. Denburg, and P. M. O'Byrne. 1997. Inhaled allergen-induced changes in bone marrow eosinophil/basophil progenitors in mild asthmatic subjects. J. Allergy Clin. Immunol. 99:S364. (Abstr.)
6. + cells from asthmatic subjects: a novel marker of progenitor cell commitment toward eosinophilic differentiation. J. Clin. Invest. 100:2466-2475.
7. + hemopoietic progenitor cells in atopic subjects. Am. J. Respir. Cell Mol. Biol. 15:645-654.
8. Strauss, L. C., S. D. Rowley, V. F. La Russa, S. J. Sharkis, R. K. Stuart, and C. I. Civin. 1986. Antigenic analysis of hematopoiesis: V. Characterization of My-10 antigen expression by normal lymphohematopoietic progenitor cells. Exp. Hematol. 14:878-886.
9. Bender, J. G., K. L. Unverzagt, D. E. Walker, W. Lee, D. E. Van Epps, D. H. Smith, C. C. Stewart, and L. B. To. 1991. Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry. Blood 77: 2591-2596.
10. + cells by IL5 and other growth factors. Cell. Immunol. 160:50-57.
11. Ohnishi, M., J. Ruhno, J. Dolovich, and J. A. Denburg. 1988. Allergic rhinitis nasal mucosal conditioned medium stimulates growth and differentiation of basophil/mast cell and eosinophil progenitors from atopic blood. J. Allergy Clin. Immunol. 81:1149-1154.
12. Otsuka, H., J. Dolovich, M. Richardson, J. Bienenstock, and J. A. Denburg. 1987. Metachromatic cell progenitors and specific growth and differentiation factors in human nasal mucosa and polyps. Am. Rev. Respir. Dis. 136:710-717.
13. Kim, Y. K., N. Nakagawa, K. Nakano, I. Sulakvelidze, J. Dolovich, and J. Denburg. 1997. Stem cell factor in nasal polyposis and allergic rhinitis: increased expression by structural cells is suppressed by in vivo topical corticosteroids. J. Allergy Clin. Immunol. 100:389-399.
14. +/Fc epsilon RI-cell population. Blood 84:2489-2496.
15. Sorden, S. D., and W. L. Castleman. 1995. Virus-induced increases in bronchiolar mast cells in Brown Norway rats are associated with both local mast cell proliferation and increases in blood mast cell precursors. Lab. Invest. 73:197-204.
16. Kitamura, Y., T. Tsujimura, T. Jippo, T. Kasugai, and Y. Kanakura. 1995. Regulation of development, survival and neoplastic growth of mast cells through the c-kit receptor. Int. Arch. Allergy Immunol. 107:54-56.
17. Hsu, S. M., L. Raine, and H. Fanger. 1981. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 29:577-580.
18. Lin, G., E. Finger, and J. C. Gutierrez-Ramos. 1995. Expression of CD34 in endothelial cells, hematopoietic progenitors and nervous cells in fetal and adult mouse tissues. Eur. J. Immunol. 25:1508-1516.
19. + cells in peripheral and cord blood by flow cytometry. Exp. Hematol. 22:1003-1010.
20. Schleimer, R. P., and B. K. Rutledge. 1986. Cultured human vascular endothelial cells acquire adhesiveness for neutrophils after stimulation with interleukin 1, endotoxin, and tumor-promoting phorbol diesters. J. Immunol. 136:649-654.
21. Kaiser, J., C. A. Bickel, B. S. Bochner, and R. P. Schleimer. 1993. The effects of the potent glucocorticoid budesonide on adhesion of eosinophils to human vascular endothelial cells and on endothelial expression of adhesion molecules. J. Pharmacol. Exp. Ther. 267:245-249.
22. + cells purified using a novel O-sialoglycoprotease. Leukemia 6:926-934.
23. Gibson, P. G., A. Girgis-Gabardo, M. M. Morris, S. Mattoli, J. M. Kay, J. Dolovich, J. Denburg, and F. E. Hargreave. 1989. Cellular characteristics of sputum from patients with asthma and chronic bronchitis. Thorax 44: 693-699.
24. Jordana, M., J. Dolovich, I. Ohno, S. Finotto, and J. Denburg. 1995. Nasal polyposis: a model for chronic inflammation. In Asthma and Rhinitis. W. W. Busse and S. T. Holgate, editors. Blackwell Scientific Publications, Boston. 156-164.
25. Galli, S. J. 1990. Biology of disease. New insights into "the riddle of the mast cells": microenvironmental regulation of mast cell development and phenotypic heterogeneity. Lab. Invest. 62:5-33.
26. Galli, S. J. 1993. New concepts about the mast cell. N. Engl. J. Med. 328: 257-265.
27. v mice: evidence that a common precursor can give rise to both "connective tissue-type" and "mucosal" mast cells. J. Immunol. 136:1378-1384.
28. Gibson, P. G., J. Dolovich, A. Girgis-Gabardo, M. M. Morris, M. Anderson, E. E. Hargreave, and J. A. Denburg. 1990. The inflammatory response in asthma exacerbation: changes in circulating eosinophils, basophils and their progenitors. Clin. Exp. Allergy 20:661-668.
29. Delia, D., M. G. Lampugnani, M. Resnati, E. Dejana, A. Aiello, E. Fontanella, D. Soligo, M. A. Pierotti, and M. F. Greaves. 1993. CD34 expression is regulated reciprocally with adhesion molecules in vascular endothelial cells in vitro. Blood 81:1001-1008.
30. Fina, E., H. V. Molgaard, D. Robertson, N. J. Bradley, P. Monaghan, D. Delia, D. R. Sutherland, M. A. Baker, and M. F. Greaves. 1990. Expression of the CD34 gene in vascular endothelial cells. Blood 75:2417-2426.
31. Healy, L., G. May, K. Gale, F. Grosveld, M. Greaves, and T. Enver. 1995. The stem cell antigen CD34 functions as a regulator of hemopoietic cell adhesion. Proc. Natl. Acad. Sci. USA 92:12240-12244.
32. Schlingemann, R. O., F. J. R. Rietveld, R. M. de Waal, N. J. Bradley, A. I. Skene, A. J. S. Davies, M. F. Greaves, J. Denekamp, and D. J. Ruiter. 1990. Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial albuminal microprocesses in the tumor stroma. Lab. Invest. 62:690-696.
33. Sankey, E. A., L. More, and A. P. Dhillon. 1990. QBEnd/10: a new immunostain for the routine diagnosis of Kaposi's sarcoma. J. Pathol. 161:267-271.
34. Norton, J., J. P. Sloane, D. Delia, and M. F. Greaves. 1993. Reciprocal expression of CD34 and cell adhesion molecule ELAM-I on vascular endothelium in acute cutaneous graft-versus-host disease. J. Pathol. 170:173-177.
35. Ramani, P., N. J. Bradley, and C. D. Fletcher. 1990. QBEND/10, a new monoclonal antibody to endothelium: assessment of its diagnostic utility in paraffin sections. Histopathology 17:237-242.
36. Schleimer, R. P., H. S. Freeland, S. P. Peters, K. E. Brown, and C. P. Derse. 1989. An assessment of the effects of glucocorticoids on degranulation, chemotaxis, binding to vascular endothelium and formation of leukotriene B4 by purified human neutrophils. J. Pharmacol. Exp. Ther. 250:598-605.
37. Suzuki, A., D. P. Andrew, J. A. Gonzalo, M. Fukumoto, J. Spellberg, M. Hashiyama, H. Takimoto, N. Gerwin, I. Webb, G. Molineux, R. Amakawa, Y. Tada, A. Wakeham, J. Brown, I. McNiece, K. Ley, E. C. Butcher, T. Suda, J. C. Gutierrez-Ramos, and T. W. Mak. 1996. CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein. Blood 87:3550-3562.
38. Schleimer, R. P. 1990. Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma. Am. Rev. Respir. Dis. 141:S59-S69.
39. Malone, D. G., R L. Wilder, A. M. Saavedra-Delgado, and D. D. Metcalfe. 1987. Must cell numbers in rheumatoid synovial tissues: correlations with quantitative measures of lymphocytic infiltration and modulation by anti-inflammatory therapy. Arthritis Rheum. 30:130-137.
40. Rak, S., M. R. Jacobson, R. M. Sudderick, K. Masuyama, S. Juliusson, A. B. Kay. Q. Hamid, O. Lowhagen, and S. R. Durham. 1994. Influence of prolonged treatment with topical corticosteroid (fluticasone propionate) on early and late phase nasal responses and cellular infiltration in the nasal mucosa after allergen challenge. Clin. Exp. Allergy 24:930-939.
41. Irani, A. A., G. Nilsson, L. K. Ashman, and L. B. Schwartz. 1995. Dexamethasone inhibits the development of mast cells from dispersed human fetal liver cells cultured in the presence of recombinant human stem cell factor. Immunology 84:72-78.