Low-concentration of perifosine surprisingly protects cardiomyocytes from oxygen glucose deprivation

Biochemical and Biophysical Research Communications

Volumn 469, Issue 3, 2016, Pages 753-760

  Zheng, Koulong ^a,b   Lu, Huihe ^b   Sheng, Zhenqiang ^b   Li, Yefei ^b   Xu, Biao ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANTONG UNIVERSITY   (China)

Author keywords

AMPK signaling; Cardiomyocytes; NADPH; Oxygen glucose deprivation (OGD) re oxygenation; Perifosine

Indexed keywords

BETA ACTIN; CYCLOPHILIN D; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PERIFOSINE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SHORT HAIRPIN RNA; VOLTAGE DEPENDENT ANION CHANNEL; CARDIOTONIC AGENT; PHOSPHORYLCHOLINE;

ANIMAL CELL; ARTICLE; CELL PROTECTION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME INHIBITION; HEART MUSCLE CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; REOXYGENATION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CARDIAC MUSCLE CELL; CELL LINE; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MOUSE; OXIDATIVE STRESS; PHYSIOLOGY; RAT;

ANIMALS; APOPTOSIS; CARDIOTONIC AGENTS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; MICE; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PHOSPHORYLCHOLINE; RATS;

EID: 84953636065     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.12.014     Document Type: Article

References (32)

1. E.G. Nabel, and E. Braunwald A tale of coronary artery disease and myocardial infarction N. Engl. J. Med. 366 2012 54 63
2. A. Steptoe, and M. Kivimaki Stress and cardiovascular disease Nat. Rev. Cardiol. 9 2012 360 370
3. J. Iqbal, P.W. Serruys, and D.P. Taggart Optimal revascularization for complex coronary artery disease Nat. Rev. Cardiol. 10 2013 635 647
4. B.L. vanderHoeven, M.J. Schalij, and V. Delgado Multimodality imaging in interventional cardiology Nat. Rev. Cardiol. 9 2012 333 346
5. K. Zheng, Z. Sheng, Y. Li, and H. Lu Salidroside inhibits oxygen glucose deprivation (OGD)/re-oxygenation-induced H9c2 cell necrosis through activating of Akt-Nrf2 signaling Biochem. Biophys. Res. Commun. 451 2014 79 85
6. A.V. Vaseva, N.D. Marchenko, K. Ji, S.E. Tsirka, S. Holzmann, and U.M. Moll p53 opens the mitochondrial permeability transition pore to trigger necrosis Cell 149 2012 1536 1548
7. L.P. Zhao, C. Ji, P.H. Lu, C. Li, B. Xu, and H. Gao Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axis Neurochem. Res. 38 2013 705 713
8. J. Fensterle, B. Aicher, I. Seipelt, M. Teifel, and J. Engel Current view on the mechanism of action of perifosine in cancer Anticancer Agents Med. Chem. 14 2014 629 635
9. J.J. Gills, and P.A. Dennis Perifosine: update on a novel Akt inhibitor Curr. Oncol. Rep. 11 2009 102 110
10. P.G. Richardson, J. Wolf, A. Jakubowiak, J. Zonder, S. Lonial, D. Irwin, and et al. Perifosine plus bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma previously treated with bortezomib: results of a multicenter phase I/II trial J. Clin. Oncol. 29 2011 4243 4249
11. H. Sun, T. Yu, and J. Li Co-administration of perifosine with paclitaxel synergistically induces apoptosis in ovarian cancer cells: more than just AKT inhibition Cancer Lett. 310 2011 118 128
12. J. Shen, L. Liang, and C. Wang Perifosine inhibits lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-alpha production via regulation multiple signaling pathways: new implication for Kawasaki disease (KD) treatment Biochem. Biophys. Res. Commun. 437 2013 250 255
13. H. Ito, Y. Hirata, M. Hiroe, M. Tsujino, S. Adachi, T. Takamoto, and et al. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes Circ. Res. 69 1991 209 215
14. W.W. Simmons, E.I. Closs, J.M. Cunningham, T.W. Smith, and R.A. Kelly Cytokines and insulin induce cationic amino acid transporter (CAT) expression in cardiac myocytes. Regulation of L-arginine transport and no production by CAT-1, CAT-2A, and CAT-2B J. Biol. Chem. 271 1996 11694 11702
15. J.J. Shao, Y. Peng, L.M. Wang, J.K. Wang, and X. Chen Activation of sphK1 by K6PC-5 inhibits oxygen-glucose deprivation/reoxygenation-induced myocardial cell death DNA Cell Biol. 34 2015 669 676
16. Z. Chen, X. Shen, F. Shen, W. Zhong, H. Wu, S. Liu, and et al. TAK1 activates AMPK-dependent cell death pathway in hydrogen peroxide-treated cardiomyocytes, inhibited by heat shock protein-70 Mol. Cell. Biochem. 377 2013 35 44
17. S.M. Jeon, N.S. Chandel, and N. Hay AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress Nature 485 2012 661 665
18. C. She, L.Q. Zhu, Y.F. Zhen, X.D. Wang, and Q.R. Dong Activation of AMPK protects against hydrogen peroxide-induced osteoblast apoptosis through autophagy induction and NADPH maintenance: new implications for osteonecrosis treatment? Cell Signal 26 2014 1 8
19. J.L. Zhang, Y. Xu, and J. Shen Cordycepin inhibits lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-alpha production via activating amp-activated protein kinase (AMPK) signaling Int. J. Mol. Sci. 15 2014 12119 12134
20. A.P. Halestrap, G.P. McStay, and S.J. Clarke The permeability transition pore complex: another view Biochimie 84 2002 153 166
21. L.S. Qin, P.F. Jia, Z.Q. Zhang, and S.M. Zhang ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis J. Exp. Clin. Cancer Res. 34 2015 57
22. Y.F. Zhen, G.D. Wang, L.Q. Zhu, S.P. Tan, F.Y. Zhang, X.Z. Zhou, and et al. P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblasts J. Cell. Physiol. 229 2014 1475 1483
23. C. Ji, Y.L. Yang, Z. Yang, Y. Tu, L. Cheng, B. Chen, and et al. Perifosine sensitizes UVB-induced apoptosis in skin cells: new implication of skin cancer prevention? Cell Signal 24 2012 1781 1789
24. D.G. Hardie, F.A. Ross, and S.A. Hawley AMPK: a nutrient and energy sensor that maintains energy homeostasis Nat. Rev. Mol. Cell Biol. 13 2012 251 262
25. M.M. Mihaylova, and R.J. Shaw The AMPK signalling pathway coordinates cell growth autophagy and metabolism Nat. Cell Biol. 13 2011 1016 1023
26. M.B. Chen, W.X. Shen, Y. Yang, X.Y. Wu, J.H. Gu, and P.H. Lu Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell J. Cell. Physiol. 226 2011 1915 1925
27. M.B. Chen, X.Y. Wu, J.H. Gu, Q.T. Guo, W.X. Shen, and P.H. Lu Activation of AMP-activated protein kinase contributes to doxorubicin-induced cell death and apoptosis in cultured myocardial H9c2 cells Cell Biochem. Biophys. 60 2010 311 322
28. G.Z. Rocha, M.M. Dias, E.R. Ropelle, F. Osorio-Costa, F.A. Rossato, A.E. Vercesi, and et al. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth Clin. Cancer Res. 17 2011 3993 4005
29. W.B. Zhang, Z. Wang, F. Shu, Y.H. Jin, H.Y. Liu, Q.J. Wang, and et al. Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition J. Biol. Chem. 285 2010 40461 40471
30. I. Janoueix-Lerosey, D. Lequin, L. Brugieres, A. Ribeiro, L. de Pontual, V. Combaret, and et al. Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma Nature 455 2008 967 970
31. K. Inoki, T. Zhu, and K.L. Guan TSC2 mediates cellular energy response to control cell growth and survival Cell 115 2003 577 590
32. M.S. Ricci, and W.X. Zong Chemotherapeutic approaches for targeting cell death pathways Oncologist 11 2006 342 357