Silencing Nrf2 impairs glioma cell proliferation via AMPK-activated mTOR inhibition

Biochemical and Biophysical Research Communications

Volumn 469, Issue 3, 2016, Pages 665-671

  Jia, Yue ^a   Wang, Handong ^a   Wang, Qiang ^a   Ding, Hui ^b   Wu, Heming ^c   Pan, Hao ^a  

^a NANJING UNIVERSITY   (China)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c The Jingdu hospital of Nanjing   (China)

Author keywords

AMPK mTOR; ATP; Glioma; Nrf2; Proliferation

Indexed keywords

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHENFORMIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NRF2; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; GLIOMA CELL; GLIOMA CELL LINE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DEPLETION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLIOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLIOMA; HUMANS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84953635329     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.12.034     Document Type: Article

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