Anti-neuroinflammatory effects of citreohybridonol involving TLR4-MyD88-mediated inhibition of NF-kB and MAPK signaling pathways in lipopolysaccharide-stimulated BV2 cells

Neurochemistry International

Volumn 95, Issue , 2016, Pages 55-62

  Cho, Kwang Ho ^a   Kim, Dong Cheol ^a   Yoon, Chi Su ^a   Ko, Won Min ^a   Lee, Seung Jun ^a   Sohn, Jae Hak ^b   Jang, Jae Hyuk ^c   Ahn, Jong Seog ^c   Kim, Youn Chul ^a   Oh, Hyuncheol ^a  

^a Wonkwang University   (South Korea)

^b Silla University   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Anti neuroinflammation; Citreohybridonol; Marine derived fungus; Mitogen activated protein kinase (MAPK); Nuclear factor kappa B (NF B)

Indexed keywords

ANTIINFLAMMATORY AGENT; CITREOHYBRIDONOL; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANDROSTANE DERIVATIVE; LIPOPOLYSACCHARIDE; MYD88 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; MOUSE; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANDROSTADIENES; ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; TOLL-LIKE RECEPTOR 4;

EID: 84953449532     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2015.12.010     Document Type: Article

References (43)

1. P. Agostinho, R.A. Cunha, and C. Oliveira Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease Curr. Pharm. Des. 16 2010 2766 2778
2. E. Ayroldi, L. Cannarile, G. Migliorati, G. Nocentini, D.V. Delfino, and C. Riccardi Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways FASEB J. 26 2012 4805 4820
3. F. Aktan iNOS-mediated nitric oxide production and its regulation Life. Sci. 75 2004 639 653
4. A.M. Bennett, and N.K. Tonks Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases Science 278 1997 1288 1291
5. M.L. Block, and J.S. Hong Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism Prog. Neurobiol. 76 2005 77 98
6. M.L. Block, L. Zecca, and J.S. Hong Microglia-mediated neurotoxicity: uncovering the molecular mechanisms Nat. Rev. Neurosci. 8 2007 57 69
7. T.S. Bugni, and C.M. Ireland Marine-derived fungi: a chemically and biologically diverse group of microorganisms Nat. Prod. Rep. 21 2004 143 163
8. A.B. Carter, K.L. Knudtson, M.M. Monick, and G.W. Hunninghake The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP) J. Biol. Chem. 274 1999 30858 30863
9. J.D. Cherry, J.A. Olschowka, and M.K. O'Banion Neuroinflammation and M2 microglia: the good, the bad, and the inflamed J. Neuroinflammation. 11 2014 98
10. W. Fenical, and P.R. Jensen Developing a new resource for drug discovery: marine actinomycete bacteria Nat. Chem. Biol. 2 2006 666 673
11. S.S. Gao, Z. Shang, X.M. Li, C.S. Li, C.M. Cui, and B.G. Wang Secondary metabolites produced by solid fermentation of the marine-derived fungus Penicillium commune QSD-17 Biosci. Biotechol. Biochem. 76 2012 358 360
12. W.H. Gerwick, and B.S. Moore Lessons from the past and charting the future of marine natural products drug discovery and chemical biology Chem. Biol. 19 2012 85 98
13. S. Ghosh, M.J. May, and E.B. Kopp NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses Annu. Rev. Immunol. 16 1998 225 260
14. T.J. Guzik, R. Korbut, and T. Adamek-Guzik Nitric oxide and superoxide in inflammation and immune regulation J. Physiol. Pharmacol. 54 2003 469 487
15. S.K. Ha, E. Moon, M.S. Ju, D.H. Kim, J.H. Ryu, M.S. Oh, and S.Y. Kim 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection Neuropharmacology 63 2012 211 223
16. C.E. Hack, E.R. De Groot, R.J. Felt-Bersma, J.H. Nuijens, R.J. Strack Van Schijndel, A.J. Eerenberg-Belmer, L.G. Thijs, and L.A. Aarden Increased plasma levels of interleukin-6 in sepsis Blood 74 1989 1704 1710
17. S.W. Himaya, B. Ryu, Z.J. Qian, and S.K. Kim Paeonol from Hippocampus kudaBleeler suppressed the neuro-inflammatory responses in vitro via NF-κB and MAPK signaling pathways Toxicol. In Vitro 26 2012 878 887
18. S. Hohki, N. Ohguro, H. Haruta, K. Nakai, F. Terabe, S. Serada, M. Fujimoto, S. Nomura, H. Kawahata, T. Kishimoto, and T. Naka Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses Exp. Eye. Res. 91 2010 162 170
19. J.W. Jeong, H.H. Lee, M.H. Han, G.Y. Kim, W.J. Kim, and Y.H. Choi Anti-inflammatory effects of genistein via suppression of the toll-like receptor 4-mediated signaling pathway in lipopolysaccharide-stimulated BV2 microglia Chem. Biol. Interact. 212 2014 30 39
20. M. Karin, and Y. Ben-Neriah Phosphorylation meets ubiquitination: the control of NF-κB activity Annu. Rev. Immunol. 18 2000 621 663
21. S. Kosemura Meroterpenoids from Penicillium citreo-viride B. IFO 4692 and 6200 hybrid Tetrahedron 59 2003 5055 5072
22. S. Kosemura, H. Miyata, S. Yamamura, K. Albone, and T.J. Simpson Biosynthetic studies on citreohybridones, metabolites of a hybrid strain KO 0031 derived from Penicillium citreo-viride B. IFO 6200 and 4692 J. Chem. Soc. Perkin Trans. 1 1994 135 139
23. M. Lappas, M. Permezel, H.M. Georgiou, and G.E. Rice Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro Biol. Reprod. 67 2002 668 673
24. L.J. Lawson, V.H. Perry, P. Dri, and S. Gordon Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain Neuroscience 39 1990 151 170
25. A. Mancino, and T. Lawrence Nuclear factor-kappaB and tumor-associated macrophages Clin. Cancer Res. 16 2010 784 789
26. R. Medzhitov Toll-like receptors and innate immunity Nat. Rev. Immunol. 1 2001 135 145
27. D.W. Moss, and T.E. Bates Activation of murine microglial cell lines by lipopolysaccharide and interferon-gamma causes NO-mediated decreases in mitochondrial and cellular function Eur. J. Neurosci. 13 2001 529 538
28. R.E. Mrak, and W.S. Griffin Interleukin-1, neuroinflammation, and Alzheimer's disease Neurobiol. Aging 22 2001 903 908
29. Y. Nakamura, Q.S. Si, and K. Kataoka Lipopolysaccharide-induced microglial activation in culture: temporal profiles of morphological change and release of cytokines and nitric oxide Neurosci. Res. 35 1999 95 100
30. D.J. Newman, and G.M. Cragg Natural products as sources of new drugs over the last 25 years J. Nat. Prod. 70 2007 461 477
31. M.D. Nguyen, J.P. Julien, and S. Rivest Innate immunity: the missing link in neuroprotection and neurodegenration? Nat. Rev. Neurosci. 3 2002 216 227
32. A.S. Noman, N. Koide, I.I. Khuda, J. Dagvadorj, G. Tumurkhuu, Y. Naiki, T. Komatsu, T. Yoshida, and T. Yokochi Thalidomide inhibits lipopolysaccharide-induced nitric oxide production and prevents lipopolysaccharide-mediated lethality in mice FEMS Immunol. Med. Microbiol. 56 2009 204 211
33. H. Ohshima, and H. Bartsch Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis Mutat. Res. 305 1994 253 264
34. E.J. Park, S. Cheenpracha, L.C. Chang, T.P. Kondratyuk, and J.M. Pezzuto Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2′-O-acetyl-alpha-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera Nutr. Cancer 63 2011 971 982
35. S.Y. Park, M.L. Jin, Y.H. Kim, Y. Kim, and S.J. Lee Anti-inflammatory effects of aromatic-turmerone through blocking of NF-κB, JNK, and p38 MAPK signaling pathways in amyloid β-stimulated microglia Int. Immunopharmacol. 14 2012 13 20
36. S. Rivest Regulation of innate immune responses in the brain Nat. Rev. Immunol. 9 2009 429 439
37. B. Rocca, and G.A. FitzGerald Cyclooxygenases and prostaglandins: shaping up the immune response Int. Immunopharmacol. 2 2002 603 630
38. U. Siebenlist, G. Franzoso, and K. Brown Structure, regulation and function of NF-kappaB Annu. Rev. Cell. Biol. 10 1994 405 455
39. M. St-Onge, N. Flamand, J. Biarc, S. Picard, L. Bouchard, A.A. Dussault, C. Laflamme, M.J. James, G.E. Caughey, L.G. Cleland, P. Borgeat, and M. Pouliot Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils Biochim. Biophys. Acta 1771 2007 1235 1245
40. M.E. Turini, and R.N. DuBois Cyclooxygenase-2: a therapeutic target Annu. Rev. Med. 53 2002 35 57
41. Y. Xu, T. Xu, Y. Wang, Y. Wang, L. He, Z. Jiang, Z. Huang, H. Liao, J. Li, J.M. Saavedra, L. Zhang, and T. Pang Telmisartan prevention of LPS-induced microglia activation involves M2 microglia polarization via CaMKKβ-dependent AMPK activation Brain Behav. Immun. 50 2015 298 313
42. K.W. Zeng, H. Fu, G.X. Liu, and X.M. Wang Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-κB and JNK/p38 MAPK pathways Int. Immunopharmacol. 10 2010 668 678
43. G. Zhang, and S. Ghosh Toll-like receptor-mediated NF-kappa B activation: a phylogenetically conserved paradigm in innate immunity J. Clin. Investig. 107 2001 13 19