Selenium Deficiency Facilitates Inflammation Following S. aureus Infection by Regulating TLR2-Related Pathways in the Mouse Mammary Gland

Biological Trace Element Research

Volumn 172, Issue 2, 2016, Pages 449-457

  Gao, Xuejiao ^a   Zhang, Zecai ^a   Li, Ying ^a   Shen, Peng ^a   Hu, Xiaoyu ^a   Cao, Yongguo ^a   Zhang, Naisheng ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Inflammation; Mastitis; S. aureus; Se; Toll like receptor 2 (TLR2)

Indexed keywords

I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; SELENIUM;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE EXPRESSION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MASTITIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SELENIUM DEFICIENCY; STAPHYLOCOCCUS INFECTION; ANIMAL; BAGG ALBINO MOUSE; DEFICIENCY; GENETICS; INFLAMMATION; METABOLISM; UDDER;

ANIMALS; FEMALE; INFLAMMATION; MAMMARY GLANDS, ANIMAL; MASTITIS; MICE; MICE, INBRED BALB C; SELENIUM; STAPHYLOCOCCAL INFECTIONS; TOLL-LIKE RECEPTOR 2;

EID: 84953388818     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-015-0614-y     Document Type: Article

References (41)

1. Fairweather-Tait SJ, Bao YP, Broadley MR, Collings R, Ford D, Hesketh JE, et al. (2011) Selenium in human health and disease. Antioxid Redox Signal 14(7):1337–1383
2. Hefnawy AE, Tortora-Perez JL (2010) The importance of selenium and the effects of its deficiency in animal health. Small Rumin Res 89(2–3):185–192
3. Sher L (2007) Possible role of selenium deficiency in the neurobiology of depression and suicidal behavior in patients with alcohol use disorders. Int J Disabil Hum De 6(3):227–230
4. McCann JC, Ames BN (2011) Adaptive dysfunction of selenoproteins from the perspective of the triage theory: why modest selenium deficiency may increase risk of diseases of aging. Faseb j 25(6):1793–1814
5. Nugroho RA, Fotedar R (2015) Effects of dietary organic selenium on immune responses, total selenium accumulation and digestive system health of marron, cherax cainii (austin, 2002). Aquac Res 46(7):1657–1667
6. Pinto A, Juniper DT, Sanil M, Morgan L, Clark L, Sies H, et al. (2012) Supranutritional selenium induces alterations in molecular targets related to energy metabolism in skeletal muscle and visceral adipose tissue of pigs. J Inorg Biochem 114:47–54
7. Zhang ZC, Gao XJ, Cao YG, Jiang HC, Wang TC, Song XJ, et al. (2015) Selenium deficiency facilitates inflammation through the regulation of TLR4 and TLR4-related signaling pathways in the mice uterus. Inflammation 38(3):1347–1356
8. Hoffmann PR, Saux CJL, Hoffmann FW, Chang PS, Bollt O, He QP, et al. (2007) A role for dietary selenium and selenoproteins in allergic airway inflammation. J Immunol 179(5):3258–3267
9. Leite HP, Nogueira PCK, Iglesias SBDO, de Oliveira SV, Sarni ROS (2015) Increased plasma selenium is associated with better outcomes in children with systemic inflammation. Nutrition 31(3):485–490
10. Zhu XK, Jiang MD, Song EQ, Jiang XJ, Song Y (2015) Selenium deficiency sensitizes the skin for UVB-induced oxidative damage and inflammation which involved the activation of p38 MAPK signaling. Food Chemical Toxicol 75:139–145
11. Hall JA, Bobe G, Vorachek WR, Kasper K, Traber MG, Mosher WD, et al. (2014) Effect of supranutritional organic selenium supplementation on postpartum blood micronutrients, antioxidants, metabolites, and inflammation biomarkers in selenium-replete dairy cows. Biol Trace Elem Res 161(3):272–287
12. Wang W, Liang DJ, Song XJ, Wang TC, Cao YG, Yang ZT, et al. (2015) Magnolol inhibits the inflammatory response in mouse mammary epithelial cells and a mouse mastitis model. Inflammation 38(1):16–26
13. Giovane R, Rezai S, Winsor R, Henderson CE (2015) Treatment for and clinical characteristics of granulomatous mastitis. Obstet Gynecol 126(2):449–450
14. Gao XJ, Guo MY, Zhang ZC, Wang TC, Cao YG, Zhang NS (2015) Bergenin plays an anti-inflammatory role via the modulation of MAPK and NF-kappa B signaling pathways in a mouse model of LPS-induced mastitis. Inflammation 38(3):1142–1150
15. Wolf C, Kusch H, Monnecke S, von Eiff C, Petzl W, Rainard P, et al. (2010) Comparative genomic and proteomic analysis of Staphylococcus aureus mastitis isolates from bovine and human origin. Reprod Domest Anim 45:59–59
16. Snel GGM, Monecke S, Ehricht R, Piccinini R (2015) Molecular characteristics of bap-positive Staphylococcus aureus strains from dairy cow mastitis. J Dairy Res 82(3):312–316
17. Zhang W, Zhang RX, Wang TC, Jiang HC, Guo MY, Zhou ES, et al. (2014) Selenium inhibits LPS-induced pro-inflammatory gene expression by modulating MAPK and NF-kappa B signaling pathways in mouse mammary epithelial cells in primary culture. Inflammation 37(2):478–485
18. Wei ZK, Yao MJ, Li YM, He XX, Yang ZT (2014) Dietary selenium deficiency exacerbates lipopolysaccharide-induced inflammatory response in mouse mastitis models. Inflammation 37(6):1925–1931
19. Expression of toll-like receptors (TLR) (2005) 2, 4, 6 and beta-defensin 5 (BNBD5) in the mammary gland is modulated in cows after experimental challenge with E-coli. Reprod Domest Anim 40:353
20. Bhatelia K, Singh K, Singh R (2014) TLRs: linking inflammation and breast cancer. Cell Signal 26(11):2350–2357
21. Wang TC, Song XJ, Zhang ZC, Guo MY, Jiang HC, Wang W, et al. (2014) Stevioside inhibits inflammation and apoptosis by regulating TLR2 and TLR2-related proteins in S. aureus-infected mouse mammary epithelial cells. Int Immunopharmacol 22(1):192–199
22. Sweeney T, Suliman H, Hollingsworth J, Piantadosi C (2008) TLR2 Deficiency Impairs Mitochondrial Biogenesis by Failure to Induce PGC-1 alpha in S. aureus Sepsis. Free Radical Bio Med 45:S139
23. Wang D, Qiao J, Zhao X, Chen T, Guan D (2015) Thymoquinone inhibits IL-1beta-induced inflammation in human osteoarthritis chondrocytes by suppressing NF-kappaB and MAPKs signaling pathway. Inflammation. doi:10.1007/s10753-015-0206-1
24. Theodorou G, Daskalopoulou M, Chronopoulou R, Baldi A, Dell’orto V, Politis I (2010) Acute mastitis induces upregulation of expression of plasminogen activator-related genes by blood monocytes and neutrophils in dairy ewes. Vet Immunol Immunopathol 138(1–2):124–128
25. Kojouri GA, Sadeghian S, Mohebbi A, Dezfouli MRM (2012) The effects of oral consumption of selenium nanoparticles on chemotactic and respiratory burst activities of neutrophils in comparison with sodium selenite in sheep. Biol Trace Elem Res 146(2):160–166
26. Wesson CA, Deringer J, Liou LE, Bayles KW, Bohach GA, Trumble WR (2000) Apoptosis induced by Staphylococcus aureus in epithelial cells utilizes a mechanism involving caspases 8 and 3. Infect Immun 68(5):2998–3001
27. Akira S, Hirano T, Taga T, Kishimoto T (1990) Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB J: Off Publ Fed Am Soc Exp Biol 4(11):2860–2867
28. Murdaca G, Spano F, Contatore M, Guastalla A, Penza E, Magnani O, et al. (2015) Infection risk associated with anti-TNF-alpha agents: a review. Expert Opin Drug Saf 14(4):571–582
29. Koca SS, Bahcecioglu IH, Poyrazoglu OK, Ozercan IH, Sahin K, Ustundag B (2008) The treatment with antibody of TNF-alpha reduces the inflammation, necrosis and fibrosis in the non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet. Inflammation 31(2):91–98
30. Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, et al. (2007) Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J Immunol 179:6933–6942
31. Ahmed EB, Wang T, Daniels M, Alegre ML, Chong AS (2011) IL-6 induced by Staphylococcus aureus infection prevents the induction of skin allograft acceptance in mice. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg 11(5):936–946
32. Boulanger D, Brouillette E, Jaspar F, Malouin F, Mainil J, Bureau F, Lekeux P (2007) Helenalin reduces Staphylococcus aureus infection in vitro and in vivo. Vet Microbiol 119(2–4):330–338
33. Chen H, Min XH, Wang QY, Leung FW, Shi L, Zhou Y, et al. (2015) Pre-activation of mesenchymal stem cells with TNF-alpha, IL-1beta and nitric oxide enhances its paracrine effects on radiation-induced intestinal injury. Sci Rep 5:8718
34. Lugade AA, Bianchi-Smiraglia A, Pradhan V, Elkin G, Murphy TF, Thanavala Y. (2011). Lipid motif of a bacterial antigen mediates immune responses via TLR2 signaling. PLoS ONE 6(5):e19781
35. Manetsch M, Seidel P, Heintz U, Che W, Hughes JM, Ge Q, et al. (2012) TLR2 ligand engagement upregulates airway smooth muscle TNF alpha-induced cytokine production. Am J Physiol Lung Cell Mol Physiol 302(9):L838–L845
36. Sun R, Zhang Y, Ma S, Qi H, Wang M, Duan J, et al. (2015). Down-regulation of MAPKs and NF-kappaB signaling is involved in rapamycin suppression of TLR2-induced inflammatory response in monocytic THP-1 cells. Microbiol Immunol 59(10):614–622
37. Li Q, Verma IM (2002) NF-kappaB regulation in the immune system. Nat Rev Immunol 2(10):725–734
38. Youn HS, Lim HJ, Choi YJ, Lee JY, Lee MY, Ryu JH (2008) Selenium suppresses the activation of transcription factor NF-kappa B and IRF3 induced by TLR3 or TLR4 agonists. Int Immunopharmacol 8(3):495–501
39. Cho IH, Lee MJ, Kim JH, Han NY, Shin KW, Sohn Y, et al. (2011) Fritillaria ussuriensis extract inhibits the production of inflammatory cytokine and MAPKs in mast cells. Biosci, Biotechnol Biochem 75(8):1440–1445
40. Fengyang L et al. (2012) Stevioside suppressed inflammatory cytokine secretion by downregulation of NF-kappaB and MAPK signaling pathways in LPS-stimulated RAW264.7 cells. Inflammation 35(5):1669–1675
41. Yang Z, Yin R, Cong Y, Zhou E, Wei Z, Liu Z, et al. (2014) Oxymatrine lightened the inflammatory response of LPS-induced mastitis in mice through affecting NF-kappaB and MAPKs signaling pathways. Inflammation 37(6):2047–2055