Mdivi-1 Protects Against Ischemic Brain Injury via Elevating Extracellular Adenosine in a cAMP/CREB-CD39-Dependent Manner

Molecular Neurobiology

Volumn 53, Issue 1, 2016, Pages 240-253

  Cui, Mei ^a   Ding, Hongyan ^a   Chen, Fangzhe ^a   Zhao, Yanxin ^b   Yang, Qi ^a   Dong, Qiang ^a  

^a FUDAN UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

Author keywords

Adenosine; cAMP response element binding protein; CD39; Cerebral ischemia; Mdivi 1; Regional cerebral blood flow

Indexed keywords

3 (2,4 DICHLORO 5 METHOXYPHENYL) 2 SULFANYL 4(3H) QUINAZOLINONE; ADENOSINE; ADENOSINE TRIPHOSPHATE; CD39 ANTIGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NEUROPROTECTIVE AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3-(2,4-DICHLORO-5-METHOXYPHENYL)-2-SULFANYL-4(3H)-QUINAZOLINONE; ADENOSINE A1 RECEPTOR; APYRASE; DNM1L PROTEIN, MOUSE; DYNAMIN; LEUKOCYTE ANTIGEN; QUINAZOLINONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; ASTROCYTE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN TISSUE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG EFFECT; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROPROTECTION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN PHOSPHORYLATION; SCORING SYSTEM; UPREGULATION; WESTERN BLOTTING; ANIMAL; BLOOD BRAIN BARRIER; C57BL MOUSE; CELL CULTURE; CONVALESCENCE; DRUG EFFECTS; EXTRACELLULAR SPACE; HYDROLYSIS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION;

ADENOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN ISCHEMIA; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DYNAMINS; EXTRACELLULAR SPACE; HYDROLYSIS; MALE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; QUINAZOLINONES; RECEPTOR, ADENOSINE A1; RECOVERY OF FUNCTION; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84953368809     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-9002-4     Document Type: Article

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