Large adipocytes function as antigen-presenting cells to activate CD4 + T cells via upregulating MHCII in obesity

International Journal of Obesity

Volumn 40, Issue 1, 2016, Pages 112-120

  Xiao, L ^a   Yang, X ^a   Lin, Y ^a   Li, S ^a   Jiang, J ^a   Qian, S ^a   Tang, Q ^a   He, R ^a   Li, X ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID; GAMMA INTERFERON; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PALMITIC ACID DERIVATIVE; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

3T3 CELL LINE; ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; BODY WEIGHT; CD4+ T LYMPHOCYTE; CELL SIZE; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GLUCOSE TOLERANCE TEST; GONADAL FAT; IN VITRO STUDY; INFANT; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LARGE ADIPOCYTE; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TISSUE METABOLISM; UPREGULATION; ANIMAL; DISEASE MODEL; GENE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; TRANSCRIPTION INITIATION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GENES, MHC CLASS II; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INSULIN RESISTANCE; INTERFERON-GAMMA; MICE; MICE, OBESE; OBESITY; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84953362988     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2015.145     Document Type: Article

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