Intrathymic Tfh/B Cells Interaction Leads to Ectopic GCs Formation and Anti-AChR Antibody Production: Central Role in Triggering MG Occurrence

Molecular Neurobiology

Volumn 53, Issue 1, 2016, Pages 120-131

  Zhang, Xiaoyan ^a,b,c   Liu, Shasha ^a,b   Chang, Ting ^a   Xu, Jiang ^a   Zhang, Chunmei ^b   Tian, Feng ^a   Sun, Yuanjie ^b   Song, Chaojun ^b   Yi, Wei ^d   Lin, Hong ^a   Li, Zhuyi ^a   Yang, Kun ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c LANZHOU GENERAL HOSPITAL   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Anti acetylcholine receptor antibody; Follicular helper T cells; Germinal centers; Myasthenia gravis; Thymus

Indexed keywords

CHOLINERGIC RECEPTOR ANTIBODY; INTERLEUKIN 21; PROTEIN BCL 6; AUTOANTIBODY; CHOLINERGIC RECEPTOR;

ADOLESCENT; ADULT; AGED; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CELL INTERACTION; CELLULAR DISTRIBUTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GERMINAL CENTER; HELPER CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE FUNCTION; MALE; MYASTHENIA GRAVIS; PERIPHERAL BLOOD MONONUCLEAR CELL; THYMOCYTE; THYMUS; CYTOLOGY; IMMUNOLOGY; INFANT; MIDDLE AGED; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTIBODY FORMATION; AUTOANTIBODIES; B-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; MIDDLE AGED; MYASTHENIA GRAVIS; RECEPTORS, CHOLINERGIC; T-LYMPHOCYTES, HELPER-INDUCER; YOUNG ADULT;

EID: 84953359458     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8985-1     Document Type: Article

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