Sheep lung segmental delivery strategy demonstrates adenovirus priming of local lung responses to bacterial lps and the role of elafin as a response modulator

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Brown, Thomas I ^a,b   Collie, David S ^b   Shaw, Darren J ^b   Rzechorzek, Ninam ^b   Sallenave, Jean Michel ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ELAFIN; GREEN FLUORESCENT PROTEIN; LIPOPOLYSACCHARIDE; MYELOPEROXIDASE;

ANIMAL CELL; ARTICLE; CELL PHAGOCYTOSIS; CONTROLLED STUDY; ENZYME ACTIVITY; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTOPENIA; MACROPHAGE CULTURE; NEUTROPHIL; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; SHEEP; TRANSGENE; VIRUS RECOMBINANT; ADENOVIRIDAE; ADENOVIRUS INFECTION; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; DOMESTIC SHEEP; DRUG EFFECTS; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN; LUNG; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; VIROLOGY;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ANIMALS; ELAFIN; GENETIC THERAPY; GENETIC VECTORS; HUMANS; LIPOPOLYSACCHARIDES; LUNG; NEUTROPHILS; SHEEP; SHEEP, DOMESTIC; TRANSGENES;

EID: 84953342753     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.01075     Document Type: Article

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